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Development of Bio-Inspired- and Wavelet-Based Hybrid Models for Reconnaissance Drought Index Modeling

The present study aimed to model reconnaissance drought index (RDI) time series at three various time scales (i.e., RDI-6, RDI-9, RDI-12). Two weather stations located at Iran, namely Tehran and Dezful, were selected as the case study. First, support vector regression (SVR) was utilized as the standalone modeling technique. Then, hybrid models were implemented via coupling the standalone SVR with

Exceptional preservation of reidite in the Rochechouart impact structure, France: New insights into shock deformation and phase transition of zircon

Reidite, the high-pressure zircon (ZrSiO4) polymorph, is a diagnostic indicator of impact events. Natural records of reidite are, however, scarce, occurring mainly as micrometer-sized lamellae, granules, and dendrites. Here, we present a unique sequence of shocked zircon grains found within a clast from the Chassenon suevitic breccia (shock stage III) from the ˜200 Ma, 20–50 km wide Rochechouart i

The neurological and neuropsychiatric spectrum of adults with late-treated phenylketonuria

Introduction: Phenylketonuria (PKU) is a rare, treatable inborn error of metabolism with frequent neurological and neuropsychiatric complications, especially in undiagnosed or insufficiently treated individuals. Given the wide range of clinical presentations and the importance of treatment implications, we here delineate the neurological and neuropsychiatric symptom spectrum in a large cohort of p

The emancipation of mindfulness from its religious context

The present paper argues that if the so-called mindfulness movement is to reach its full potential it needs to emancipate from its religious context and ally itself fully with psychological science. The argument that mindfulness meditation needs a religious context for ethical reasons is untenable. Although mindfulness skills may well be used for un-ethical purposes, this applies equally to both r

Management of asthma in childhood : Study protocol of a systematic evidence update by the Paediatric Asthma in Real Life (PeARL) Think Tank

Introduction Clinical recommendations for childhood asthma are often based on data extrapolated from studies conducted in adults, despite significant differences in mechanisms and response to treatments. The Paediatric Asthma in Real Life (PeARL) Think Tank aspires to develop recommendations based on the best available evidence from studies in children. An overview of systematic reviews (SRs) on p

Optical investigations and characterization of soot of different morphology and maturity

The formation path from small poorly absorbing incipient soot to larger fractal-like strongly absorbing black soot is extensive, and along this path the optical and physicochemical properties of the soot evolve. Soot emitted into the atmosphere may originate from some stage of this process, which will result in a wide spectrum of carbonaceous aerosols in the atmosphere which may interact with the

What you say and what I hear-Investigating differences in the perception of the severity of psychological and physical violence in intimate partner relationships

The correct communication of the severity of violence is essential in the context of legal trials, custody cases, support of victims, etc., for providing fair treatment. A narrator that communicates their experiences of interpersonal violence may rate the seriousness of the incident differently than a rater reading the narrator’s text, suggesting that there exist perceptual differences (PD) in sev

An Hp scale for complete Pick spaces

We define by interpolation a scale analogous to the Hardy Hp scale for complete Pick spaces, and establish some of the basic properties of the resulting spaces, which we call Hp. In particular, we obtain an Hp-Hq duality and establish sharp pointwise estimates for functions in Hp

Polyesters with indole as sustainable aromatic component

Plastics are widely used in our daily lives and industry. Unfortunaltely, most plastics are produced from non-renewable fossil resources. The transition toward sustainable resources such as various biomass is critically important for the future of plastic industry and the whole society. Polyesters consitute a major class of plastics, which are widely used in textiles, packaging and other applicati

Optimising prophylaxis in haemophilia A : The ups and downs of treatment

The classical goals of haemophilia A treatment are to prevent bleeds, minimise the risk of long-term complications associated with joint damage, and improve quality of life by maintaining appropriate factor VIII [FVIII] levels. The dose and frequency of FVIII replacement therapies required to reduce bleeds is now known to vary amongst individuals, and may change for the same individual over time,

Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

Large-scale human exome sequencing can identify rare protein-coding variants with a large impact on complex traits such as body adiposity. We sequenced the exomes of 645,626 individuals from the United Kingdom, the United States, and Mexico and estimated associations of rare coding variants with body mass index (BMI). We identified 16 genes with an exome-wide significant association with BMI, incl

Defect guided conduction in graphene-derivatives and MoS2 : Two-dimensional nanomaterial models

The realization of unique scientific phenomena in two-dimensional nanomaterials (2DNMs) has led to their applications in several electronic fields; making it imperative to understand the conduction mechanism of charge carriers in such systems. Though several studies have been conducted on 2DNMs with pristine crystallinity, the inevitable presence of defects in the crystals requires careful conside

Surface guided radiotherapy

AbstractModern radiotherapy aims to treat the decease while minimizing the radiation dose to the adjacent normal tissue, to minimize acute and late effects of the treatment. The foremost technological approaches have been intensity modulated radiotherapy (IMRT) and intensity modulated proton therapy (IMPT) in combination with image guided radiotherapy (IGRT). IMRT and IMPT is characterized by a moModern radiotherapy aims to treat the decease while minimizing the radiation dose to the adjacent normal tissue, to minimize acute and late effects of the treatment. The foremost technological approaches have been intensity modulated radiotherapy (IMRT) and intensity modulated proton therapy (IMPT) in combination with image guided radiotherapy (IGRT). IMRT and IMPT is characterized by a more confo

A highly-detailed anatomical study of normal pericardial structures as revealed by in-vivo computed tomography and magnetic resonance images and ex-vivo novel 3D reconstructions from Visible Human Server

The pericardial cavity, sinuses, and recesses are frequently depicted on Computed Tomography (CT) and Magnetic Resonance (MR). We here review the normal human pericardial structures as provided by MR imaging of young, healthy subject and CT scans acquired after iatrogenic coronary dissection. We compared such radiological information with cadaveric axial and sagittal sections of the human body pro

Urban water supply automation - Today and tomorrow

Automation is a collection of a whole set of theories and methods to make a system work automatically as intended, in our case the urban water supply system. A critical feature of automation is the feedback principle: a sensor is measuring a certain variable, e.g. a concentration; a computer tests that the measurement is valid; a computer algorithm calculates and decides what should be corrected;

Dynamical Grooming meets LHC data

In this work, we analyse the all-orders resummation structure of the momentum sharing fraction, zg, opening angle, θg, and relative transverse momentum, kt,g, of the splitting tagged by the Dynamical Grooming procedure in hadronic collisions. We demonstrate that their resummation does non-exponentiate and it is free of clustering logarithms. Then, we analytically compute the probability distributi