Using an atomic model with a simplified-sequence-based potential, the folding properties of several different peptides are studied. Both alpha-helical (Trp cage, F-s) and beta-sheet(GB1p, GB1m2, GB1m3, Betanova, LLM) peptides are considered. The model is able to fold these different peptides for one and the same choice of;parameters, and the melting behaviour of the peptides (folded population aga

Popular Abstract in Swedish Sammanväxningar i buken är en normal reaktion efter skador i bukhinnan och utvecklas efter ett inflammatoriskt svar och det efterföljande läkningsförloppet. Många sammanväxningar bildas inom 24-48 timmar efter skadan och tillbakabildas normalt efter 5-7 dagar. Många av de sammanväxningar som kvarstår kan ses som en obalans i de system som bildar ärr (fibros) och löser dIntraabdominal adhesions are formed after most operations and a limited number of studies have to examine the long-term spectrum of adhesion-related disorders and the cost associated with this. Only a few numbers of antiadhesive agents are available which, however, do not decrease the actual morbidity that follows intraabdominal adhesions, such as small bowel obstruction, infertility and pain. Fut

Decision support systems (DSS) have generated high expectations as a tool to support activated sludge operation because of their ability to represent heuristic reasoning and to handle large amounts of qualitative, uncertain and low-accuracy data. Previous applications have been satisfactory to control simple problems, when static reasoning and literature-based solutions were enough. However to fac

Enterobacteriaceae are frequently isolated from food products and it is essential to have methods for correct identification for both food hygiene and epidemiology reasons. Phenotypic methods are not always sufficient and have to be supplemented by DNA based methods. In the present study, 70 strains of Enterobacteriaceae derived from milk, fish and meat that had previously been identified by Biolo

Dålig inomhusmiljö är ett problem i dagens bostäder. orsakerna är flera, bl a introducerandet av nya obeprövade material, olämpliga konstruktioner som medför fuktproblem samt dålig luftomsättning kombinerat med hög täthet. I Staffanstorp utanför Lund uppfördes under 1996 ett experimenthus som formgivits av arkitekt Karin Grundström. Målsättningen var att åstadkomma en sund och estetiskt tilltaland

A coupled system, consisting of a conventional ion-exchange column and a chiral column, was used for separation of the D- and L-enantiomers as constituents of an amino acid mixture. The ion-exchange column was connected to an amino acid analyser and the eluents necessary for the chiral column were delivered by an HPLC pump. With this on-line system the D- and L-forms of eight of the proteinogenic

BACKGROUND: In urban Guinea-Bissau, adults with a vaccinia scar had better survival but also a higher prevalence of HIV-2 infection. We therefore investigated the association between vaccinia scar and survival and HIV infection in a rural area of Guinea-Bissau. METHODOLOGY/PRINCIPAL FINDINGS: In connection with a study of HIV in rural Guinea-Bissau, we assessed vaccinia and BCG scars in 193 HIV-1

The preliminary results of a palynological investigation of 62 samples from the southern section of a sedimentary sequence exposed at Fossilryggen in the Vestfjella mountain range in Dronning Maud Land, Antarctica are reported. The sequence, which is cut by dolerite dykes, is considered to have been deposited in a near-shore marine environment. Palynomorphs recovered show high degrees of thermal a

The purpose of this study was to examine whether the quality of measured x-ray beam data can be judged from how well the data agree with a semiempirical formula. Tissue-phantom ratios (TPR) and output factors for several accelerators in the energy range 4-25 MV were fitted to the formula, separating the dose contributions from primary and phantom-scattered photons. The former was described by expo

In this paper, we describe centering and noncentering methodology as complementary techniques for use in parametrization of broad classes of hierarchical models, with a view to the construction of effective MCMC algorithms for exploring posterior distributions from these models. We give a clear qualitative understanding as to when centering and noncentering work well, and introduce theory concerni

Corlorectal cancer affects 5% of individuals in the Western world and heredity is estimated to cause at least 10% of the tumors. Defective mismatch repair (MMR) is a tumorigenic mechanism through which about 15% of colorectal cancer develops and this feature characterizes tumors associated with Hereditary Nonpolyposis Colorectal Cancer (HNPCC) or Lynch syndrome. The underlying molecular mechanism

Bacillus subtilis strain 168 encodes two flavocytochromes P450, Cyp102A2 and Cyp102A3. The cyp102A3 gene is preceded by, and organized in an operon with, a gene for a transcriptional regulator, encoded by fatR. The paralogous gene, cyp102A2, is most likely transcribed as a mono-cistronic message. We show that fatR encodes a protein that binds to an operator sequence that is present upstream of its

Popular Abstract in Swedish Syftet med avhandlingen har varit att försöka förstå bronsålderns samhälle och ideologi utifrån bebyggelsens inneboende symbolik, utformning och struktur. I alla samhällen utgör hushållet den minsta sociala enheten. Huset och hushållen utgör centrum för människors liv. Hur människorna har valt att organisera sin tillvaro kan ha skett i en samverkan med den övergripande The purpose of this thesis is an attempt to comprehend the society and the ideology of the Bronze Age from the inherent symbolism, shape and structure of buildings. In every society, the smallest social unit is the household. The house and the household are central in the lives of people. They made their choices to organize their existence in a symbiotic cooperation with the general cosmology and

Aim To identify the effect of climate change on selected plant species representative of the main vegetation types in the Faroe Islands. Due to a possible weakening of the North Atlantic Current, it is difficult to predict whether the climate in the Faroe Islands will be warmer or colder as a result of global warming. Therefore, two scenarios are proposed. The first scenario assumes an increase in

The myosin heavy chain stoichiometry and the force-velocity relation have been determined in the myometrium of the non-pregnant and pregnant rat. The relative proportions of the slower migrating heavy chain (MHC1) greatly exceeded that of the faster migrating heavy chain (MHC2) as shown by electrophoresis on SDS 4%-polyacrylamide gels. The ratios of MHC1/MHC2 were 2.2/1 in the non-pregnant rats, 2