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Hydration of the Zwitterionic and Protonated Forms of Glycine Betaine Probed by Soft X-ray Emission Spectroscopy Coupled with Chemometrics

Soft X-ray absorption and emission spectra of glycine betaine (GB) have been measured at the O K-edge in neutral and strongly acidic solutions. The absorption spectra of the neutral solutions have a resonance peak at 532.6 eV, assigned to the transition to the π∗ orbital, whereas in the acidic solutions, the peak is shifted by -0.3 eV. The emission spectra taken as a function of the GB concentrati

Predicting the severity of the grass pollen season and the effect of climate change in Northwest Europe

Allergic rhinitis is an inflammation in the nose caused by overreaction of the immune system to allergens in the air. Managing allergic rhinitis symptoms is challenging and requires timely intervention. The following are major questions often posed by those with allergic rhinitis: How should I prepare for the forthcoming season? How will the season's severity develop over the years? No country yet

Examining the sensitivity of the terrestrial carbon cycle to the expression of El Niño

The El Niño - Southern Oscillation (ENSO) influences the global climate and the variability in the terrestrial carbon cycle on interannual timescales. Two different expressions of El Niño have recently been identified: (i) central Pacific (CP) and (ii) eastern Pacific (EP). Both types of El Niño are characterised by above-average sea surface temperature anomalies at the respective locations. Studi

Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells

The process of hematopoiesis is subject to substantial ontogenic remodeling that is accompanied by alterations in cellular fate during both development and disease. We combine state-of-the-art mass spectrometry with extensive functional assays to gain insight into ontogeny-specific proteomic mechanisms regulating hematopoiesis. Through deep coverage of the cellular proteome of fetal and adult lymp

Base-catalyzed depolymerization of kraft lignin for valuable chemical production

Lignin is one of the three predominant biopolymers that make up plants together with cellulose and hemicellulose, and it is the only plant component that is based on aromatic units. The industrial kraft pulping process generates large amounts of lignin, which is currently used to generate heat for the process. The subject of this thesis is the valorization of kraft lignin into valuable chemicals.

Dopamine Cell Therapy : From Cell Replacement to Circuitry Repair

Cell therapy for Parkinson's disease (PD) is aimed to replace the degenerated midbrain dopamine (mDA) neurons and restore DA neurotransmission in the denervated forebrain targets. A limitation of the intrastriatal grafting approach, which is currently used in clinical trials, is that the mDA neurons are implanted into the target area, in most cases the putamen, and not in the ventral midbrain wher

Unmarried or less-educated patients with mantle cell lymphoma are less likely to undergo a transplant, leading to lower survival

It is unknown how many mantle cell lymphoma (MCL) patients undergo consolidation with autologous hematopoietic cell transplantation (AHCT), and the reasons governing the decision, are also unknown. The prognostic impact of omitting AHCT is also understudied. We identified all MCL patients diagnosed from 2000 to 2014, aged 18 to 65 years, in the Swedish Lymphoma Register. Odds ratios (ORs) and 95%

Acid-triggering of light-induced charge-separation in hybrid organic/inorganic molecular photoactive dyads for harnessing solar energy

H+ modulated charge-transfer in photoexcited covalent polyoxometalate-bodipy conjugates is described. The hybrid organic/inorganic molecular photoactive dyads are based on Keggin-type polyoxometalates (POMs, where KM = [PM11O39] and M = Mo or W) covalently grafted via an organotin linker to a bodipy (BOD) photosensitizer. The relative potentials of the photosensitizer and POM are aligned such that

Female Peacekeepers’ Added Burden

Twenty years since the adoption of UN Security Council Resolution 1325 there is an almost unanimous call for an increased number of uniformed women in peace operations from policy-makers and multilateral organizations. This continuous push for the inclusion of more women is often justified by arguments about an increased operational effectiveness related to women's ‘added value’: both implicitly a

No Place like Home? Postdeployment Reintegration Challenges Facing South African Peacekeepers

This study focuses on soldiers returning from peacekeeping missions and the challenges they experience adapting to the home environment in the postdeployment phase. The article focuses on South African peacekeepers returning from missions in Darfur/Sudan, the Democratic Republic of Congo, and Burundi. Interviews with 50 South African peacekeepers on the challenges they face in terms of their homec

Modernitetens kritiska samvete : En samhällsvetenskap som gör nytta

Samhällsvetenskapen gör samtiden begriplig. Genom att kritiskt granska politik, ekonomi, kommunikation och organisation ger den djupare förståelse för det moderna samhällets förtjänster och problem. Dock bara om den utförs väl, och på allvar tillåts skärskåda gängse föreställningar och företeelser. Under fem övergripande rubriker: Kritisk, Kvalitativ, Konsekvensneutral, Krävande och Konstruktiv, v

A Logic of its Own: the external presence in the Sahel

The political underperformance, socio-economic grievances, widespread poverty and expansion of terrorist networks in the Sahel region are commonly framed as security risks to both the region itself and to Europe. The heavy international security presence in the region, including a UN peacekeeping mission with a robust mandate, a US Africa Command drone base, three EU missions, a large French-led c

Challenges with Security Force Assistance in Niger: Understanding Local Context and Aligning Interests

Since the attacks the 11th of September 2001 in the US, there has been a strong increase in security force assistance (SFA) to fragile states with the aim of professionalising security forces, preventing violent extremist organisations (VEO) from exploiting state fragility and, in cases where this has not succeeded, of fighting the latter. At the same time, a shift has taken place with regard to t

Context Matters – Why Africa Should Tailor its Own Measures to Fight Covid-19

African governments have been faster than most of their European counterparts in imposing measures to deal with the COVID-19 outbreak despite dealing with numerous other challenges. However, context matters, and for Africa, the political and socioeconomic consequences of the lockdown measures may cause more havoc than the actual virus.This brief identifies political, economic and social risks rela