Bone morphogenetic protein 10 (BMP-10) is crucial for endothelial cell signaling via activin receptor-like kinase 1 (ALK1), a pathway central to vascular homeostasis and angiogenesis. Dysregulated BMP-10 signaling contributes to cardiovascular diseases and cancer, highlighting the need to control ALK1-mediated endothelial responses to BMP-10 for therapeutic development. BMP-10 biosynthesis involve

Background: Current guidelines for initial management of traumatic brain injury (TBI) support decision making, but they are rarely validated. The Scandinavian guideline for management of children with TBI (SNC16) was developed to minimise the use of cranial computed tomography (cCT) without compromising safety, but the performance of the guideline in a real-world population is unknown. We aimed to

Is being informed about a nudge detrimental to its effect? This paper reports results from an experimental online study testing the effects of transparency on the effectiveness of a default nudge while accounting for psychological reactance and response time. Overall and in line with earlier studies, we find no negative effect of transparency on average behaviour. Adding to the previous discussion

The widespread adoption of lithium-ion batteries (LIBs) for energy storage has introduced significant fire risks, particularly in confined and restricted environments such as tunnels. This study investigated thermal runaway (TR) behavior in a model tunnel at ventilation speeds ranging from 0 m/s to 2.5 m/s, using LiFePO4 (LFP) and LiNixCoyMnzO2 (NCM) batteries. The experiments identified two criti

Objective: The present study compared individual personality traits and demographic variables, i.e. sex, age, and socioeconomic status, in explaining mental health in a large representative adolescent Swedish high school survey. Method: This data collection on 15- to 18-year-olds (N = 10,288, response rate 79 %) was conducted in 2024 and included, for the first time, a brief Big Five personality m

Beslut om utlämning fattas av regeringen efter yttrande från Riksåklagaren. Om den eftersökte inte samtycker till utlämning yttrar sig även Högsta domstolen (HD). I den här analysen behandlar JP Infonets expert Christoffer Wong, universitetslektor i straff- och straffprocessrätt, processen i utlämningsärenden. Han diskuterar särskilt frågan om och när HD:s prövning bör omfatta förenligheten med Eu

Electron paramagnetic resonance of Cr3+ ions in β -Ga2O3 is investigated using terahertz spectroscopic ellipsometry under magnetic field sweeping, a technique that enables the polarization resolving capabilities of ellipsometry for magnetic resonance measurements. We employed a single-crystal chromium-doped β -Ga2O3 sample, grown by the Czochralski method, and performed ellipsometry measurements a

We describe a magnetic relation in analogy to the well-known dielectric Lyddane-Sachs-Teller relation [R. H. Lyddane et al., Phys. Rev. 59, 673 (1941)PHRVAO0031-899X10.1103/PhysRev.59.673]. This magnetic relation follows directly from the model equations for nuclear induction due to fast oscillating electromagnetic fields [F. Bloch, Phys. Rev. 70, 460 (1946)PHRVAO0031-899X10.1103/PhysRev.70.460] a

Plant-based alternatives are considered microbiologically safe; however, recent studies have raised concerns about hygienic quality. Additionally, the relationship between microbiological safety and polyphenolic content in fermented products remains unexplored. This study assessed the potential of four autochthonous Lactiplantibacillus plantarum strains (3, 5, 9, and 10) to impact microbial com

Background and purpose: There is an urgent need to improve patient-selection to surgical treatment in advanced ovarian cancer as our results showed that cytoreductive surgery was without effect or even detrimental in a yet unknown subgroup of women. With an ageing population, 30% of women with advanced ovarian cancer in Sweden are >75 years. Nevertheless, there are no recommendations on patient-se

Background: Brain raspberries are histologically defined microvascular entities that are highly prevalent in the neocortex. Increased cortical raspberry density occurs in vascular dementia, but also with advancing age. Here, we examined the raspberry density in two neurodegenerative diseases, wherein vascular alterations distinct from conventional vascular risk factors have been indicated: frontot

Detailed characterization of the unsteady combustion behaviors of individual aluminum (Al) droplets is scarce, due to the experimental challenges in resolving the transient phenomena at the micrometer scale. In this work, we spatiotemporally elucidate the complex interplay, including droplet coalescence, eruption, and fragmentation, of individually burning Al droplets and alumina (Al2O3) products,

Independent estimation and verification of fossil CO2 emissions on a regional and national scale are crucial for evaluating the fossil CO2 emissions and reductions reported by countries as part of their nationally determined contributions (NDCs). Top-down methods, such as the assimilation of in situ and satellite observations of different tracers (e.g., CO2, CO, Δ14CO2, XCO2), have been increasing

This paper explores whether the experience of a recession during early adulthood shapes individuals’ prosocial attitudes. The analysis uses survey responses to experimentally validated questions that measure prosocial attitudes for approximately 64,000 respondents in 74 countries. The identification approach exploits variation in recession experiences across 75 different birth cohorts. We find tha

In this introduction, we explain how the chapters in this volume give support to the idea that different accounts of active cognition in the history of philosophy directly or indirectly respond to Aristotle’s account of cognition in his De anima.