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We study variational shrinkage in the sparse normal means model and compare it with the corresponding exact Bayes shrinkage rule. The focus is on the excess quadratic risk of the variational posterior mean. Using a squared-loss decomposition, we show that this excess risk is bounded by the discrepancy between the variational and exact Bayes estimators together with the benchmark Bayes risk. This y
This paper introduces the ALF cipher family, designed for format-preserving encryption. The key strategy is to leverage AES-NI instructions to achieve a high software performance while also providing 128-bit security. A central part of the paper is the design of an AES-related bit-oriented block cipher called ALF-n-t, with a block size ranging from 16 to 127 bits. The core of the design is byte-or
Background: This retrospective cohort study compared short-term outcomes between robotic-assisted and conventional laparoscopic surgery for rectal cancer using data from the Swedish Colorectal Cancer Registry. Method: All patients undergoing elective minimally invasive surgery for rectal cancer between 2014 and 2021 and registered in the Swedish Colorectal Cancer Registry were assessed for eligibi
Methane (CH₄) and carbon dioxide (CO₂) emissions from northern peatlands areimportant components of the global greenhouse gas (GHG) balance and are highlysensitive to climate change and permafrost degradation. This thesis investigatesspatial and temporal patterns of GHG fluxes across peatland ecosystems, with aparticular focus on the environmental controls regulating CH₄ and CO₂ exchange.Field mea
In pulmonary arterial hypertension (PAH), increased pulmonary vascular resistance (PVR) causes right ventricular pressure overload and left ventricular (LV) underfilling. We investigated LV mechanics and their prognostic value in PAH using cardiovascular magnetic resonance (CMR)-derived LV pressure-volume (PV) loops. We included 96 patients (median age 64 years, 70% women) with PAH and clinically
Objectives: Trauma-focused cognitive behavioural therapy (TF-CBT) is the established first-line treatment for paediatric post-traumatic stress disorder (PTSD), but access to evidence-based care remains limited. This study aimed to evaluate the feasibility and acceptability of a therapist-guided, 12 week, internet-delivered TF-CBT (iTF-CBT) programme for adolescents with PTSD and to explore prelimi
In response to the finite nature of many resources and their significant impact on climate change, governments worldwide have developed political strategies and concepts to promote the transition towards a bioeconomy, emphasizing the use of renewable bio-based resources across various sectors. In particular, the construction sector can adopt wood as an alternative to carbon-intensive materials. Ho
Objective This study developed a European job exposure matrix (EuroJEM) for psychosocial work factors in order to examine their prospective associations with diagnosed depression in three register-based Nordic cohorts. Methods National, gender-specific psychosocial JEM from Finland, Norway, and Sweden were evaluated for similarities in exposures, exposure definitions, and occupational coding. The
This paper introduces a new method to search for unresolved binary stars in open star clusters. The work aims at improving the approach introduced previously, which employs the (H − W2) − W1 versus W2 − (BP − K) photometric diagram. This diagram, in tandem with the Gaia color–magnitude diagram and using theoretical isochrones as reference sequences, is used to estimate the binary star fraction and
Feminist social reproduction theories and approaches capture multiple scales of analysis, from everyday care work within households to the reproductive aspects of welfare systems such as health and education. Feminist thinkers draw our attention to the gendered, racialized, and classed intersections embedded within production processes, by analyzing the ecological, biological, and social dimension
Metallaphosphinidenes, [M–P], contain open-shell single-atomic phosphorus but typically display uncontrollable reactivity, preventing their utilization to selectively construct elusive functional groups. Here, we report an iridium phosphaethynolate complex, [(PCP)Ir(PCO)] (2), in a halide metathesis with Na(OCP). Photolysis of 2 leads to a bimetallic, side-on bound {P2} motif, [{(PCP)(OC)Ir}2(η2,η
Soil acidification driven by anthropogenic nitrogen (N) deposition is a growing global threat to forest health. Aside from direct nutrient-related effects, as forest soils acidify, severe reductions in ectomycorrhizal (EcM) fungi abundance and diversity follow. This is worrisome, as EcM fungi are essential for tree nutrient acquisition and are important catalysts of mineral weathering and soil for
In order to meet the demands of consumers, personal care products, like any other product, must undergo constant innovation in order to stay up to date with consumer needs, preferences whilst conforming to commercial regulation. Here, the works contained within this thesis firstly aim to gain greater understanding of current actives in aluminium antiperspirant products, through the manufacture and
The luminescence properties of double molybdates can be changed by modifying their crystal structure through stoichiometric variations while preserving elemental composition. In this study, the structural and luminescent characteristics of K5Nd(MoO4)4 (K5Nd) and KNd5(MoO4)8 (KNd5) are investigated. Powder X-ray diffraction analysis revealed that K5Nd can be described by either a trigonal or monocl
Denna avhandling undersöker vad äldre hemtjänstanvändare gör för att få hemtjänsten att fungera i vardagen och vad deras handlingar visar om svensk hemtjänst som omsorgsregim. Avhandlingen bygger vidare på forskning som fokuserar på äldre personers egna perspektiv på den omsorg deras vardag genomsyras av.I avhandlingens fem artiklar visas och analyseras hur hemtjänstanvändare i betydande utsträcknThis dissertation examines what older home care users do to make home care arrangements work in everyday life and what their actions show about Swedish home care as a care regime. It builds on and extends research focusing on older people’s own perspectives on care. Across the dissertation’s five articles, care users are shown to contribute extensively to the provision of the services they rely on
Background – Cognitive impairment is a clinically significant, non-motor symptom of Parkinson’s disease (PD) commonly associated with reduced quality of life, increased caregiver burden, and higher risk of progression to dementia. Mild cognitive impairment in PD (PD-MCI) is expressed heterogeneously, with likely prognostic implications. This pilot study evaluated the feasibility and preliminary di
Purpose: High-dose methotrexate (HDMTX) is a cornerstone in pediatric oncology, but delayed methotrexate elimination (DME) can cause severe toxicity. Rescue therapy typically combines folinic acid (FA) and glucarpidase (GP), yet current guidelines recommend pausing FA around GP administration due to presumed interference. This study aimed to determine whether FA affects GP efficacy in metabolizing
In this work, we explored the catalytic decomposition of methanol to syngas at 300 °C using intermetallic Ni3Sn2 nanoparticles (NPs) synthesized via a chemical route. Our study employed a comprehensive approach combining operando Ambient Pressure soft X-ray absorption spectroscopy with a suite of ex situ techniques─including X-ray diffraction, X-ray photoelectron spectroscopy, electron microscopy,
