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Rural supply chain management: a multidimensional framework for future research in Europe

Innovations affect urban and rural areas differently. Although thesupply chain management (SCM) literature recognises the interaction betweenurban and rural areas in terms of flow of products, people and communication,the rural perspective is clearly missing. An inductive approach was appliedusing an interdisciplinary panel of international experts to explore challengesand opportunities in the int

Inequalities in child immunization coverage in Ghana : evidence from a decomposition analysis

Childhood vaccination has been promoted as a global intervention aimed at improving child survival and health, through the reduction of vaccine preventable deaths. However, there exist significant inequalities in achieving universal coverage of child vaccination among and within countries. In this paper, we examine rural-urban inequalities in child immunizations in Ghana. Using data from the recen

Functional Screening Identifies MicroRNA Regulators of Corin Activity and Atrial Natriuretic Peptide Biogenesis

Atrial natriuretic peptide (ANP) represents an attractive therapeutic target in hypertension and heart failure. The biologically active form of ANP is produced by the cardiac serine protease corin, and modulation of its activity might therefore represent a novel approach for ANP augmentation. MicroRNAs (miRNAs) are pervasive regulators of gene expression, but their potential role in regulating cor

Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy

Background: Hyperlipidaemia is a major risk factor for cardiovascular disease, and atherosclerosis is the underlying cause of both myocardial infarction and stroke. We have previously shown that the Pro251 variant of perilipin-2 reduces plasma triglycerides and may therefore be beneficial to reduce atherosclerosis development. Objective: We sought to delineate putative beneficial effects of the Pr

Environmental exposures in young adults with declining kidney function in a population at risk of Mesoamerican nephropathy

Objectives There is an epidemic of Mesoamerican nephropathy (MeN) in Central America, where sugarcane production is prominent. Numerous causes are proposed, but to date limited evidence supports any one hypothesis. A nested case-control study using biosamples from a rural, community-based follow-up study of 350 young adults from Northwest Nicaragua at risk of MeN was conducted with the aim of char

Does Mobility across Universities Raise Scientific Productivity?

Using a highly comprehensive new data set on Swedish researchers, we investigate the effects of inter-university mobility on researcher productivity. Our study suggests substantial gains from mobility on scientific output. The empirical analysis addresses selection using inverse probability treatment censoring weights. We find that mobility induces a long-lasting increase in a researcher's publica

Serum complexes between C1INH and C1INH autoantibodies for the diagnosis of acquired angioedema

Acquired angioedema due to C1-inhibitor (C1INH) deficiency (AAE) is caused by secondary C1INH deficiency leading to bradykinin-mediated angioedema episodes. AAE typically presents in adulthood and is associated with B cell lymphoproliferation. Anti-C1INH autoantibodies (antiC1INHAbs) are detectable in a subset of AAE cases and considered a hallmark of the disease. When free antiC1INHAbs and malign

Spinal infektion med ryggmärgs­påverkan kräver snabba åtgärder - Genomgång av Ivo-anmälningar visar att fördröjd handläggning kan ge allvarliga restsymtom

Seventeen cases of infections in spinal structures were reported 2010-2017 to the Swedish Health and Social Care Inspectorate (IVO), a government agency responsible for supervising health care, for missed or delayed diagnosis. All patient records were scrutinized in order to find underlying causes and common factors. The delayed diagnoses were equally found among men and women and most frequent in

Ett forskningsinstitut expanderar : IUI från 1950 till 1966

2014 publicerades Ett forskningsinstitut växer fram – IUI från grundandet till 1950. I den här boken fortsätter historien om Industriens Utredningsinstitut (numera Institutet för Näringslivsforskning). Den period som behandlas är 1950–66, en period då institutet leddes av dynamiska chefer, Jan Wallander (1953–61) och Ragnar Bentzel (1961–66), och dess ställning som Sveriges ledande fristående fors

IT-säkerhet och sårbarhet: Hur arbetar kommuner med krishantering?

Den här studien bidrar med sina resultat till kunskapen kring hur kommuner arbetar med krishantering, ett område som tidigare studier visat kräver mer forskning (Choi och Brower, 2006; Marschall, 2015; Jarman et al., 2000; Mullin och Rubado, 2017). Den här studien bidrar även med kunskap kring hur kommuner kan samverka såväl inom den egna organisationen som med andra aktörer över organisatoriska g

Aerosol mass yields of selected biogenic volatile organic compounds - A theoretical study with nearly explicit gas-phase chemistry

In this study we modeled secondary organic aerosol (SOA) mass loadings from the oxidation (by O3, OH and NO3) of five representative biogenic volatile organic compounds (BVOCs): isoprene, endocyclic bond-containing monoterpenes (α-pinene and limonene), exocyclic double-bond compound (β-pinene) and a sesquiterpene (β-caryophyllene). The simulations were designed to replicate an idealized smog chamb

A South Atlantic island record uncovers shifts in westerlies and hydroclimate during the last glacial

Changes in the latitudinal position and strength of the Southern Hemisphere westerlies (SHW) are thought to be tightly coupled to important climate processes, such as cross-equatorial heat fluxes, Atlantic Meridional Overturning Circulation (AMOC), the bipolar seesaw, Southern Ocean ventilation and atmospheric CO2 levels. However, many uncertainties regarding magnitude, direction, and causes and e

On short-ranged pair-potentials for long-range electrostatics

In computer simulations, long-range electrostatic interactions are surprisingly well approximated by truncated, short-ranged pair potentials. Examples are reaction field methods; the Wolf method; and a number of schemes based on cancellation of electric multipole moments inside a cut-off region. These methods are based on the assumption that the polarization of the neglected surroundings can be in

Improving capability assessments for disaster risk management

There is an urgent need for society to find more effective ways to reduce the impact of disastrous events. One way is to proactively increase actors’ response capability. Capability assessments play an essential role in these disaster risk management efforts. Currently, capability is assessed using indicator and index methods that focus on available resources. Such methods may not provide the best