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Objectives: Patients with systemic lupus erythematosus (SLE) often display modest elevations of C-reactive protein (CRP) despite raised disease activity and increased interleukin (IL-) 6. We asked to what extent IL-6 levels, the CRP polymorphism rs1205, and the type I interferon (IFN) gene signature affects the basal CRP levels in patients with SLE during a quiescent phase of the disease. Methods:
The past decade has brought tremendous progress in diagnostic and therapeutic options for cerebrovascular diseases as exemplified by the advent of thrombectomy in ischemic stroke, benefitting a steeply increasing number of stroke patients and potentially paving the way for a renaissance of neuroprotectants. Progress in basic science has been equally impressive. Based on a deeper understanding of p
Background: Dizziness and pain are common complaints that often appear concomitantly, with or without a causal relationship. However, these symptoms might maintain and exacerbate each other and other co-morbidities. Therefore, adequate rehabilitation may have to include an expanded focus on other deficits and preconditions, especially in older adults and in patients. Objective: To understand how f
Using data between 2003 and 2016, this paper assesses the degree and evolution of socio-economic inequalities in maternal health outcomes in four African countries. The study measures the trends of socio-economic inequalities in maternal healthcare and assesses the sources of socio-economic inequalities in maternal health through a decomposition approach. We find cross-country differences in the e
Objective: The aim of this study was to describe the change of antibiotic prescribing in pre-school children in the municipalities of the former Copenhagen County in Denmark and Skåne County in Sweden after 20 years of antibiotic stewardship effort. Furthermore, the variation in the prescribing of antibiotics between the municipalities and the correlation between municipal adult educational level
Aim of this deliverable is to describe the work being carried out for the conceptual design of the Open-Platform and Factsheets for GDSI, in accordance with the project plan of Simona Miraglia (Postdoc2-DTU-BYG) in collaboration with Carlos Moraleda Melero (Research assistant), Sebastian Thöns (DTU-BYG) and Peter Fantke (DTU-MAN). A brief literature review regarding basi
This report describes a system model for assessing and updating the condition state and reliability of bridge structures utilizing inspection and monitoring data. The system model was developed on the basis of an existing continuous single-cell prestressed concrete box girder. The system model consists of two integrated sub-models: a condition model for predicting the deterioration state of the bo
This report describes concepts for an intelligent bridge on the basis of a reliability-based condition assessment utilizing inspection and monitoring data. The central part of the concept is a model describing the bridge system. The overall bridge model is com-prised of deterioration models and a mechanical system model of the structure. The model is a-priori characterized by the i
This paper reviews historical developments and recent challenges in full scale bridge testing and introduces results- and hypotheses related to an ongoing bridge testing research project. This research project encompasses full scale bridge testing in conjunction with bearing capacity analysis as well as related contact- and non-contact monitoring procedures combined with a decision analytical appr
