Car-sharing systems with electric vehicles are an alternative to reduce commuting times in big cities and also to mitigate air pollution. Car-sharing exists in 1100 cities around the world. These systems have had positive effects in the cities, replacing between 9 and 23 private vehicles for each car. This document proposes a public car-sharing system for Bogotá. The article focuses on the design

A large strand of research holds that democracy with its broad representation and electoral accountability is beneficial for the provision of public goods. Yet, there is a large variation in how democracies perform, indicating that democratic institutions alone do not suffice for securing citizens’ wellbeing. Recent studies have stressed the equal importance of state capacity for public goods deli

The band offset between wurtzite (wz) and zinc-blende (zb) GaAs is an important fundamental parameter in polytype heterostructure engineering. Since the interface has a type-II band alignment, it is reasonably straightforward to measure the band offset using photoluminescence (PL) e.g. on nanowires containing heterostructures between wz and zb GaAs. It has, however, been found that the transition

Anaerobic co-digestion allows for under-utilised digesters to increase biomethane production. The organic fraction of municipal solid waste (OFMSW), i.e., food waste, is an abundant substrate with high degradability and gas potential. This paper investigates the co-digestion of mixed sludge from wastewater treatment plants and OFMSW, through batch and continuous lab-scale experiments, modelling, a

High-energy surface X-ray diffraction (HESXRD) provides surface structural information with high temporal resolution, facilitating the understanding of the surface dynamics and structure of the active phase of catalytic surfaces. The surface structure detected during the reaction is sensitive to the composition of the gas phase close to the catalyst surface, and the catalytic activity of the sampl

Feature stability, time and tempo of change, and the role of genealogy versus areality in creating linguistic diversity are important issues in current computational research on linguistic typology. This paper presents a database initiative, DiACL Typology, which aims to provide a resource for addressing these questions with specific of the extended Indo-European language area of Eurasia, the regiFeature stability, time and tempo of change, and the role of genealogy versus areality in creating linguistic diversity are important issues in current computational research on linguistic typology. This paper presents a database initiative, DiACL Typology, which aims to provide a resource for addressing these questions with specific of the extended Indo-European language area of Eurasia, the regi

Vocabulary for subsistence and technology may vary a great deal in their degree of borrowability, depending on time, place, inherent subsistence and technology, and the situation of the borrowing. In cross-linguistic typological studies of borrowability, these words tend to group somewhere from middle to high in borrowability, depending on lexical concept (Haspelmath & Tadmor, 2009).We have co

Languages borrow words when there is a need for it, all languages contain loanwords, and no part of the lexicon is entirely “loan-proof”. These are statements about lexical borrowing that are typically found in linguistic textbooks (Hock and Joseph 1996). Further, we know that that there are large discrepancies in the borrowability of different lexical concepts, where core vocabulary domains (sens

The Israeli-Palestinian conflict, or the Israeli-Arab conflict/the conflict in the Middle East, as it was called in official EC/EU language all the way up to the 2000s, presented what was widely perceived in Europe to be a golden opportunity for the EC to unite its foreign policy in the late 1960s and early 1970s. However, as important that goal was, many European politicians—from left to right—si

Professor Inga Marie Nilsson (1923-99) was a pioneer in the field of bleeding and thrombo-embolic disorders and made several major scientific contributions during her career. To honour her memory, colleagues from all over the world were invited to cover several aspects of haemostasis by giving state-of-the-art lectures at an international symposium in Malmö on September 22-23, 2000, chaired by Pro

Prenatal diagnosis of haemophilia A or B is possible by means of chorionic villus biopsy in the first trimester which traces the mutation or informative genetic markers. If possible, direct gene analysis of the mutation is preferred, The natural starting point in haemophilia A is to ascertain whether the disease is due to inversion in the X-chromosome, which is the case in almost half of the sever

Factor XIII deficiency is a rare autosomal recessive bleeding disorder that is characterized by defective crosslinking of fibrin and poor resistance to fibrinolysis. We have characterized seven mutations in FXIII A-subunit gene: Four missense mutations (Met242->Thr. Arg252->Ile, Arg326->Gln and Leu498->Pro) and three nonsense mutations (Arg661->Stop, delT Phe8 and a splicing defect T->C at positio

The existence of two genetic variants (allotypes) of normal human factor IX is used for carrier detection in three families with severe and one with mild haemophilia B. By analysis of IX:Ag with two different monoclonal antibodies in 93 members of the families, allelic assignment is shown to be a complement in carrier diagnosis to genotypic DNA studies. Allelic assignment makes possible a reliable

Haemophilia A and haemophilia B are congenital X-linked bleeding disorders caused by deficiency of coagulation factor VIII (FVIII) and IX (FIX), respectively. The preferred treatment option for patients with haemophilia is replacement therapy. For patients with severe disease, prophylactic replacement of coagulation factor is the treatment of choice; this has been shown to reduce arthropathy signi

Mild haemophilia is defined by factor levels between 0.05 and 0.40 IU/mL and is characterised by traumatic bleeds. Major issues associated with mild haemophilia are that it may not present for many years after birth, and that awareness, even within families, may be low. Methodological problems exist in diagnosis, such as inconsistencies in results obtained from different assays used to measure fac

Atrial fibrosis can be estimated noninvasively by magnetic resonance imaging (MRI) using late gadolinium enhancement (LGE), but diastolic dysfunction is clinically assessed by transthoracic echocardiography (TTE), and rarely by MRI. This study aimed to evaluate well-established diastolic parameters using MRI, and validate them with TTE and left ventricular (LV) filling pressures, and to study the

Background Dose/area and reading paradigms for gold patch testing are controversial and not standardized worldwide. Objectives The aims of this study were to determine the optimum patch test dose of gold sodium thiosulfate (GST) in a hydrogel (HYD) and to establish GST HYD safety/efficacy and further characterize normal morphology and time course of GST reactions. Methods Twenty gold-allergic pati

Purpose: Carriers of CDKN2A mutations have high risks of melanoma and certain other cancers. In this study we examined the occurrence of tumors among CDKN2A wild type (wt) members of melanoma-prone families with CDKN2A mutations. Methods: Swedish and US melanoma-prone families with CDKN2A mutations were included. Data was collected on tumors diagnosed among family members. Among the CDKN2A mutated