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Objective: To evaluate the effects of excluding fatty tissue in QSM of human knee cartilage. Materials and methods: Gradient echo images from 18 knee-healthy volunteers were acquired, from which chemical shift corrected field perturbation maps were calculated. Based on these, QSM maps were reconstructed using morphology enabled dipole inversion and one of three masking alternatives: (1) excluding
Background: Low adherence to lipid-lowering therapy (LLT) after myocardial infarction (MI) is associated with increased risk of recurrent cardiovascular events and death. However, little is known about long-term adherence patterns following treatment interruptions. The aim of this study was to describe adherence trajectories in MI patients following a LLT treatment gap, and model the impact of dif
Organoid systems hold promise as miniaturized in vitro platforms that model developmental and pathological processes. However, the engineering of human bone marrow organoids (BMOs) has been a long-standing challenge. Recently, the field has witnessed the emergence of BMO-like systems, a potential paradigm shift for the study of human hematopoiesis and associated niche elements. Published protocols
Background: Continuity of care (CoC) is essential for effective primary health care (PHC), yet Swedish PHC has historically exhibited low levels of continuity. The Swedish Patient Choice Reform introduced privatization and market-oriented principles into PHC, leading to increased utilization and growing inequities in service use driven by socioeconomic disparities and misalignment with health care
Background Preserved ratio impaired spirometry (PRISm) is a spirometry pattern of interest regarding incident airflow obstruction and higher mortality risk. We applied a proteomic approach to gain more insight into the biological mechanisms associated with PRISm. Methods From the population-based Swedish Cardiopulmonary Bioimage Study (SCAPIS), participants in the Main (n=4835) and Pilot (n=1054)
The Dandy: A People’s History of Sartorial Splendour challenges the traditional notion of dandyism as an upper-class phenomenon, expanding it to include working-class figures like clerks, shop assistants, and labourers. The text reveals how dandyism becomes a widespread cultural movement, one that Beau Brummell sparks in the early nineteenth century and that continues through the 1960s mod culture
Vaccine hesitancy and anti-vaccination attitudes are becoming increasingly problematic in several Western countries where diseases that were nearly extinct are coming back. We here explore the role of perceived social support in understanding anti-vaccination attitudes. We argue that perceptions about having social support for one′s position may influence anti-vaccination attitudes among some soci
We analyze the stability of the logit evolutionary dynamics in population games, possibly with multiple heterogeneous populations. For general population games, we prove that, on the one hand, strict Nash equilibria are asymptotically stable under the logit dynamics for low enough noise levels, on the other hand, a globally exponentially stable logit equilibrium exists for sufficiently large noise
Many companies leverage the creativity of their employees to gather ideas for innovations. These ideas are collected, saved, and evaluated via platforms known as corporate ideation systems. Moderated ideation systems (ideation 2.0) emerged as a solution to address the limitations of traditional, rather passive ideation systems (ideation 1.0). In this study, we apply a qualitative mixed-method appr
Heart and lung transplantation remain the primary treatments for end-stage organ failure; yet organ shortages and ischemia-reperfusion injury (IRI) limit their success. Extended criteria donors (ECDs) have expanded the donor pool; however, prolonged cold ischemia times increase the risk of primary graft dysfunction (PGD). Static cold storage (SCS), the standard organ preservation method, is subopt
Embodiment has slowly been integrated as a category of analysis in (critical) military studies. In this article, we argue that embodiment–and related concepts such as body, affects and emotions–has become prevalent concerns over the 10-year consolidation of the intellectual project of the journal CMS. We propose an inquiry organized around three axes: situating current debates in the broader field
Cyanobacteria are bioactive compounds that produce toxins known as harmful algal blooms, posing serious threats to humans and marine life. Consequently, developing a robust monitoring framework to track and forecast the growth of such blooms is critical. The present work aims to understand the key environmental drivers influencing cyanobacterial bloom dynamics along the Southeast coast of India us
This letter addresses loss of packets in a wireless fronthaul link being interpreted as channel errors for the service link. This may occur if, for instance, User Equipment (UE) is served by a radio unit in an Uncrewed Aerial Vehicle (UAV) via a wireless fronthaul link to a baseband unit (BU) on the ground. The fronthaul packet loss leads to a mismatch between the real and estimated channel state,
This study investigates properties of mastics produced with 70/100 neat bitumen, three mineral fillers (granite, quartz-granite, and diorite), and a lime-based active filler at filler-to-bitumen (F/B) ratios of 40%, 50%, and 60%. The physical, geometrical, and mineralogical properties of the fillers were assessed. Their influence on mastics' behaviour was evaluated using conventional penetration a
This study aims to explore the mechanism through which Yishen Jiangtang Decoction (YSJTD) regulates endoplasmic reticulum stress (ERS)-mediated NOD-like receptor thermal protein domain associated protein 3 (NLRP3) inflammasome to improve diabetic nephropathy (DN) in db/ db mice. Thirty db/ db mice were randomly divided into the model group, YSJTD group, ERS inhibitor 4-phenylbutyric acid (4-PBA) g
Background: Pancreatic cancer continues to retain the highest mortality rate among all major organ cancers. New strategies for early detection are being proposed to increase long-term survival. A plethora of molecular markers are discovered yearly, but so far none have demonstrated screening utility. Summary: Promising discovery technologies include affinity-based proteomics and ddPCR. In the vali
We present a genome assembly from an individual female Podarcis tiliguerta (Tyrrhenian Wall Lizard; Chordata; Lepidosauria; Squamata; Lacertidae). The assembly contains two haplotypes with total lengths of 1 462.31 megabases and 1 394.94 megabases. Most of haplotype 1 (99.26%) is scaffolded into 20 chromosomal pseudomolecules, including the W and Z sex chromosomes. Most of haplotype 2 (99.2%) is s
Neuromuscular disorders (NMDs) are disorders of the motor unit (motor neuron diseases, diseases of the peripheral nerves, neuromuscular junction diseases, and diseases affecting the muscle fibers). A common denominator of these diseases is muscle atrophy and progressive weakness. Quantitative assessments of muscle function are therefore essential to follow disease progression, to understand the as
