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ObjectiveTo explore sex and age differences in Patient-Reported Outcomes Measures (PROMs) and adherence to digital osteoarthritis (OA) self-management intervention.MethodsA register-based study with data from an OA digital self-management intervention. PROMs and adherence were collected at baseline and/or 3 ​month follow-up: ‘pain intensity’ in hip/knee (best/worst: 0–10), ‘activity impairments' (

Background: There is an unmet clinical need for novel therapies addressing the residual risk in patients receiving guideline preventive therapy for coronary heart disease. Experimental studies have identified a pro-atherogenic role of the oxidized LDL receptor LOX-1. We investigated the association between circulating soluble LOX-1 (sLOX-1) and the risk for development of myocardial infarction. Me

In this chapter, we will lay the foundation for the case studies in the subsequent chapters. To this end, we will make explicit our understanding of populism, which links the individual contexts discussed in the remainder of this book. In this book, we define populism as a political strategy and/or practice, realised in discourse, that is based on a dichotomy between "the people", who are unified

One of the most challenging and warning issues that have globally been introduced is the climate change and its effects on water resources. Climate change due to global warming has increased temperature and evaporation potential and has changed the precipitation pattern as well as precipitation amount in different seasons. The aim of this study is to assess the impact of climate change on the hydr

En välkänd svårighet för inlärare av L2-svenska är komplexiteten kring definithet, bestämdhet och artikelbruk (DBA). Flera studier har indikerat att inlärare som saknar morfologisk bestämdhetsmarkering i sitt L1 har svårare för strukturer inom DBA, men att även inlärare med motsvarande strukturer i sitt L1 har rapporterats ha svårigheter. I denna artikel redogör vi för hur den komplexitet som DBA A well-known difficulty for learners of L2 Swedish is the complexity of definiteness in form and meaning, together with article use. Several studies have indicated that learners lacking morphological definiteness in their L1 struggle more with structures within this area although learners with corresponding structures in their L1 also have issues. This article describes how this area’s complexity

Acetylation is a wood modification used to increase the durability. Although it is known that the wood moisture content is lowered, the exact mechanisms behind the increased durability are not known. However, since fungi need water in different locations for different purposes the location and state of water is most probably of importance in addition to the total moisture content. In a previous st

Land subsidence, a silent death, occurs due to various factors like significant reduction in groundwater (GW) levels. It is a widespread phenomenon with irreparable consequences on buildings, infrastructures, and, in severe cases, groundwater aquifers. This study aims to assess the impact of river flow on the acceleration and control of land subsidence in an arid and semi-arid region. To achieve t

The management of water resources in a basin can be challenging due to the sharing of water resources among multiple stakeholders and conflicting interests. This often results in imbalanced water resource development across the basin. While small and medium-sized projects are efficiently implemented in the headwater and upstream areas, the commissioning of large reservoirs faces delays due to the

Numerous assays exist to measure aggressive behaviour in honeybees, most of them using free-flying bees under natural conditions, with results often variable due to environmental factors. Our study describes a novel, laboratory-based Petri dish assay that uses a moving target treated with the alarm pheromone component isoamyl acetate (IAA). In this assay, aggression levels can be measured in indiv

BACKGROUND: Bronchodilator responsiveness (BDR) in asthma involves both the central and peripheral airways but is primarily relieved with beta-2-agonists and evaluated by spirometry. To date, antimuscarinics can be added as a reliever medication in more severe asthma. We hypothesize that combining both short-acting beta-2 agonist (SABA) and short-acting muscarinic antagonist (SAMA) could also impr

Anthropogenic stressors such as agricultural intensification, climate change, andincreased densities of non-native managed bees used for crop pollination arecontributing to bee declines. Understanding how and why bees have responded topast environmental changes is crucial for predicting future ones and enablingmitigation to maintain the functioning of both natural and agricultural ecosystems.The a

BACKGROUND: Neoadjuvant chemotherapy (NACT) for early breast cancer can make breast-conserving surgery more feasible and might be more likely to eradicate micrometastatic disease than might the same chemotherapy given after surgery. We investigated the long-term benefits and risks of NACT and the influence of tumour characteristics on outcome with a collaborative meta-analysis of individual patien

Cartesian impedance control is a type of motion control strategy for robots that improves safety in partially unknown environments by achieving a compliant behavior of the robot with respect to its external forces. This compliant robot behavior has the added benefit of allowing physical human guidance of the robot. In this paper, we propose a C++ implementation of compliance control valid for any

BACKGROUND: The administration of endocrine therapy for 5 years substantially reduces recurrence rates during and after treatment in women with early-stage, estrogen-receptor (ER)-positive breast cancer. Extending such therapy beyond 5 years offers further protection but has additional side effects. Obtaining data on the absolute risk of subsequent distant recurrence if therapy stops at 5 years co