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Proteios (http://www.proteios.org) is an initiative for the development of a comprehensive open source system for storage, organization, analysis, and annotation of proteomics experiments. The Proteios platform is based on existing principles for proteomics data publishing and data exchange.
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Review of an edition of the diaries of Metta Lillie, 1737-1750.
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Purpose The aim of this paper is to provide insights into, and perspectives on, the transformation of mindsets for logisticians. We argue that by exploring paradoxes inherent in the efficiency-focused paradigm of today, a strategic mindset can emerge in which central logistics management issues can be addressed, understood, and dealt with in order to enhance supply chain effectiveness and innovati
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BMP receptors determine the intensity of BMP signals via Smad1 C-terminal phosphorylations. Here we show that a finely controlled cell biological pathway terminates this activity. The duration of the activated pSmad1Cter signal was regulated by sequential Smad1 linker region phosphorylations at conserved MAPK and GSK3 sites required for its polyubiquitinylation and transport to the centrosome. Pro