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Consequences of planetary migration on the minor bodies of the early solar system

Pebble accretion is an efficient mechanism that is able to build up the core of the giant planets within the lifetime of the protoplanetary disc gas-phase. The core grows via this process until the protoplanet reaches its pebble isolation mass and starts to accrete gas. During the growth, the protoplanet undergoes a rapid, large-scale, inward migration due to the interactions with the gaseous prot

The antibiotic challenge : Justifications for antibiotic usage in the world of medicine

This chapter is a micro-sociological exploration of the justifications that Danish general practitioners adopt to support antibiotic usage in their clinical practices. Based on qualitative in-depth interviews with 21 general practitioners in Denmark, the chapter looks upon the clinic as a particular social world (a justificatory regime) in which different antibiotic treatment strategies are qualif

Semiconductor eco-materials for water treatment

In the current chapter two semiconductor materials are being assessed as ecomaterials of choice for key applications in the water business. Ultraviolet lightemitting diodes, UV-LEDs, based on III-Nitride ultraviolet emitters like GaN, InGaN, and AlGaN and semiconductor oxides like TiO 2 , ZnO, or WO 3 can be used as eco-materials for disinfection and pollutant removal in water, respectively. Lo

Thermal design and performance prediction of a shell condenser for closed-cycle underwater vehicles

The shell condenser is a key component for the underwater vehicles. To study its heat transfer performance and flow characteristics and to design a more efficient structure, a mathematical model is generated to simulate condensation inside the straight and helical channels. The model combines empirical correlations and MATLAB based on an iterative algorithm. Here, quality is used as a sign of the

Impact of water drop presence on diffusion parameters of PEFC gas diffusion layers

A polymer electrolyte fuel cell (PEFC) produces electrical energy thanks to the electrochemical reaction carried out inside the cell. During the energy conversion, water molecules are also produced in the cathode side and this can affect the diffusion parameters of the gas diffusion layers (GDLs). The generated water-drops due to the reaction may block the reactant gases and produce material oxida

In-situ heat treatment study on the nanocrystalline Cr 2 O 3 film using an environmental scanning electron microscope

In this work, the surface morphology changes of nanocrystalline Cr 2 O 3 film deposited on Si wafer during the heating process were observed in-situ by means of an environmental scanning electron microscope (ESEM). The Cr 2 O 3 film cracked at high temperature due to the cause of thermal stress; the corresponding crack area percentages on the film surface were real-time evaluated using image

Mind in Universe : On the Origin, Evolution, and Distribution of Intelligent Life in Space

This chapter discusses the question of mind in space. It aims to lay the ground for an emerging research field, astrocognition, studying the origin, evolution, and distribution of intelligence in the universe. The first section concerns terrestrial intelligence, the cognitive phenomena involved in human search for extraterrestrial life and intelligence. Intelligence could be explained as a cogniti

Human Mind in Space and Time : Prolegomena to a Cognitive History

The last decades have seen a noticeable increase in cognitive science studies that have changed the understanding of human thinking. Its relevance for historical research cannot be overlooked any more. Cognitive history could be explained as the study of how humans in history used their cognitive abilities in order to understand the world around them and to orient themselves in it, but also how th

The Axiomatic-Deductive Ideal in Early Modern Thinking : A Cognitive History of Human Rationality

Euclid completed his geometrical proofs in the Elements (c. 300BC) with the abbreviation “QED” (quod erat demonstrandum). This phrase was not only used in mathematics in the early modern period, but also in deductive proofs in physics, astronomy, philosophy, and ethics. This chapter is a cognitive- historical interpretation of the axiomatic-deductive ideal that consists of some widely accepted pro

Lp-PLA 2 activity and mass and CRP are associated with incident symptomatic peripheral arterial disease

Long follow up is needed in prospective cohort study evaluation of plasma biomarkers for incident peripheral arterial disease (PAD) Middle-aged PAD-free individuals from the cardiovascular cohort of the Malmö Diet and Cancer study (n = 5550; 1991–94) were followed prospectively for a median time of 23.4 years. The plasma biomarkers lipoprotein-associated phospholipase A2 (Lp-PLA 2 ) activity and

Glucocorticoid-resistant B cell acute lymphoblastic leukemia displays receptor tyrosine kinase activation

The response of childhood acute lymphoblastic leukemia (ALL) to dexamethasone predicts the long-term remission outcome. To explore the mechanisms of dexamethasone resistance in B cell ALL (B-ALL), we generated dexamethasone-resistant clones by prolonged treatment with dexamethasone. Using RNA-sequencing and high-throughput screening, we found that dexamethasone-resistant cells are dependent on rec

Evaluation of the Lund deep geothermal exploration project in the Romeleåsen Fault Zone, South Sweden : a case study

The bedrock of Skåne, the southernmost province of Sweden, has been targeted for geothermal feasibility studies since the late 1970s. An exploration project concerning the geothermal potential in the Romeleåsen Fault Zone was launched outside the town of Lund in 2001. Besides geophysical imaging of the thrust fault zone, the investigations included drilling and investigations of a 3701.8-m-deep e

Differing impact of clinical factors on the risk of fracture in younger and older women in the general population and an osteoporosis clinic population

Summary: This study assesses the impact of risk factors for fracture in women aged 80+ and 60–79. The results suggest that risk assessment which fits younger women may not be suited for the 80+ strata as many common risk factors are less predictive in the older compared to the younger cohort. Purpose: This study assesses whether the impact of classical risk factors for fracture due to osteoporosis

The effect of locally delivered cisplatin is dependent on an intact immune function in an experimental glioma model

Several chemotherapeutic drugs are now considered to exert anti-tumour effects, by inducing an immune-promoting inflammatory response. Cisplatin is a potent chemotherapeutic agent used in standard medulloblastoma but not glioblastoma protocols. There is no clear explanation for the differences in clinical efficacy of cisplatin between medulloblastomas and glioblastomas, despite the fact that cisp

Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia

Hyperdiploidy, i.e. gain of whole chromosomes, is one of the most common genetic features of childhood acute lymphoblastic leukemia (ALL), but its pathogenetic impact is poorly understood. Here, we report a proteogenomic analysis on matched datasets from genomic profiling, RNA-sequencing, and mass spectrometry-based analysis of >8,000 genes and proteins as well as Hi-C of primary patient samples f

Multiple-Input Multiple-Output Model Predictive Control of a Diesel Engine

Traditionally, diesel engine control has had to rely on indirect feedback variables and empirical open-loop maps because direct measurements of the variables representing high-level objectives, such as emissions, have not been available in production engines. With new sensors being developed, the opportunity opens to design the controller directly based on high-level objectives. In this paper, we