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On short-ranged pair-potentials for long-range electrostatics

In computer simulations, long-range electrostatic interactions are surprisingly well approximated by truncated, short-ranged pair potentials. Examples are reaction field methods; the Wolf method; and a number of schemes based on cancellation of electric multipole moments inside a cut-off region. These methods are based on the assumption that the polarization of the neglected surroundings can be in

Improving capability assessments for disaster risk management

There is an urgent need for society to find more effective ways to reduce the impact of disastrous events. One way is to proactively increase actors’ response capability. Capability assessments play an essential role in these disaster risk management efforts. Currently, capability is assessed using indicator and index methods that focus on available resources. Such methods may not provide the best

Local Routing in Sparse and Lightweight Geometric Graphs

Online routing in a planar embedded graph is central to a number of fields and has been studied extensively in the literature. For most planar graphs no O(1)-competitive online routing algorithm exists. A notable exception is the Delaunay triangulation for which Bose and Morin [Bose and Morin, 2004] showed that there exists an online routing algorithm that is O(1)-competitive. However, a Delaunay

Beredskap i framtida energisystem. En analys med utgångspunkt i Energimyndighetens ""Fyra Framtider"

I denna studie analyseras förutsättningarna för att bygga energiberedskap i framtida energisystem. Utgångspunkt tas i Energimyndighetens scenarier "Fyra framtider" och de framtidsutvecklingar av energisystemet och samhället i stort som presenteras i dessa. De områden som studeras särskilt i denna rapport är digitalisering, ökad elektrifiering, decentralisering av elproduktionen, ökat beroende av v

Civilt försvar i gråzon

Som en följd av det säkerhetspolitiska läget har planeringen för och återuppbyggnaden av ett civilt försvar påbörjats i Sverige. I många sammanhang talar man samtidigt om att Sverige är utsatt för gråzonshot och det förutsätts att det civila försvaret ska kunna hantera dessa hot. Förståelsen för vad dessa hot innebär är dock otillräcklig. I denna rapport introduceras tre områden som bedöms som cen

Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture

Background: Most in vitro studies of potential osteoarthritis (OA) therapies have used cartilage monocultures, even though synovium is a key player in mediating joint inflammation and, thereby, cartilage degeneration. In the case of interleukin-1 (IL-1) inhibition using its receptor antagonist (IL-1Ra), like chondrocytes, synoviocytes also express IL-1 receptors that influence intra-articular IL-1

Candidate for Laser Cooling of a Negative Ion : High-Resolution Photoelectron Imaging of Th

Laser cooling is a well-established technique for the creation of ensembles of ultracold neutral atoms or positive ions. This ability has opened many exciting new research fields over the past 40 years. However, no negatively charged ions have been directly laser cooled because a cycling transition is very rare in atomic anions. Efforts of more than a decade currently have La- as the most promisin

C-fibers may modulate adjacent Aδ-fibers through axon-axon CGRP signaling at nodes of Ranvier in the trigeminal system

BACKGROUND: Monoclonal antibodies (mAbs) towards CGRP or the CGRP receptor show good prophylactic antimigraine efficacy. However, their site of action is still elusive. Due to lack of passage of mAbs across the blood-brain barrier the trigeminal system has been suggested a possible site of action because it lacks blood-brain barrier and hence is available to circulating molecules. The trigeminal g

Progression in Glaucoma

The treatment of glaucoma is focused on reducing the intraocular pressure to a level at which progression is impeded. A diagnosis of glaucoma is not considered certain until progression is confirmed, and thus detecting progression is a central aspect in both the diagnosing and the monitoring of glaucoma patients. Progression can be identified either through examination of either functional changes