Background: Factor H regulates the alternative pathway of complement. The protein has three heparin-binding sites, is synthesized primarily in the liver and copurifies from platelets with thrombospondin-1. Factor H mutations at the C-terminus are associated with atypical hemolytic uremic syndrome, a condition in which platelets are consumed. Objectives The aim of this study was to investigate if f

Objectives The Patient Health Questionnaire-9 (PHQ-9) is one of the most commonly used measures for screening, diagnosing and monitoring of depression. So far, four studies have examined some of the psychometric properties of Persian version of PHQ-9 in physical and psychiatric patients; however, some aspects of its psychometrics have not yet been adequately evaluated in the student population. Th

We introduce a new family of continuous distributions and study the mathematical properties of the new family. Some useful characterizations based on the ratio of two truncated moments and hazard function are also presented. We estimate the model parameters by the maximum likelihood method and assess its performance based on biases and mean squared errors in a simulation study framework.

In this paper, a flexible modified extended exponential power life testing (MEEPLT) distribution is proposed. The MEEPLT distribution has increasing, decreasing and bathtub hazard rate function. The MEEPLT density is arc, left skewed, right-skewed and symmetrical shaped. The MEEPLT distribution is developed on the basis of the generalized Pearson differential equation. Some structural and mathemat

Industrial control systems (ICSs) are a significant part of industry and they play an important role in monitoring and controlling industrial processes. Traditionally, ICSs have been isolated from the Internet, and thereby secured from various Internet-based security threats. In recent years, since the cloud can provide huge advantages regarding storage and computing resources, industry has been m

Wild chimpanzee populations in West Africa (Pan troglodytes verus) have dramatically decreased as a direct consequence of anthropogenic activities and infectious diseases. Little information is currently available on the epidemiology, pathogenic significance, and zoonotic potential of protist species in wild chimpanzees. This study investigates the occurrence and genetic diversity of intestinal an

Proteolytic cleavage of thrombin generates C-terminal host defense peptides exerting multiple immunomodulatory effects in response to bacterial stimuli. Previously, we reported that thrombin-derived C-terminal peptides (TCPs) are internalized in monocytes and macrophages in a time- and temperature-dependent manner. In this study, we investigated which endocytosis pathways are responsible for the i

The MM500 meta-study aims to establish a knowledge basis of the tumor proteome to serve as a complement to genome and transcriptome studies. Somatic mutations and their effect on the transcriptome have been extensively characterized in melanoma. However, the effects of these genetic changes on the proteomic landscape and the impact on cellular processes in melanoma remain poorly understood. In thi

A public housing company has applied a new renovation strategy, comprising no standards raising and thus rent-raising measures, in 20% of its apartments. Prior to renovation, the tenants were given the opportunity to choose renovation options involving different standards and costs after renovation. The purpose of the study is to follow up and give feedback on the renovation strategy. The aim was

Background: Patients with dementia have an increased risk of developing epilepsy, es-pecially in patients with vascular dementia and Alzheimer’s disease. In selecting the optimal an-ti-epileptic drug (AED), the possible side effects such as drowsiness and worsening of cognitive function should be taken into consideration, together with co-morbidities and type of epilepsy. Objective: The current sy

ZnO-water nanofluid in an inner pipe was experimentally investigated to improve the thermal efficiency of double-pipe heat exchangers. In this work, a 57.6% increase in the Nusselt number was obtained at Re = 14,340 when the ZnO-water nanofluid flowed through a helically corrugated tube. It was found that helical corrugation played a more important role in heat transfer enhancement than thermophys

Background: Severe hereditary alpha-1-antitrypsin deficiency (AATD) is a known risk factor for the early development of pulmonary emphysema and COPD, especially in smo-kers. By the Swedish national screening programme carried out from 1972 to 1974, a cohort of individuals with severe (PiZZ) AATD was identified and has been followed up regularly. The aim of this study was to investigate health stat

In this paper we study structure from motion problems for 1D radial cameras. Under this model the projection of a 3D point is a line in the image plane going through the principal point, which makes the model invariant to radial distortion and changes in focal length. It can therefore effectively be applied to uncalibrated image collections without the need for explicit estimation of camera intrin

The ability for groups to engage in collective action depends on a variety of factors, ranging from social organization to resources to political opportunities amongst others. Yet, on a much more basic level, collective action is dependent on the ability of individuals to come together to interact and coordinate action, or in other words, to create a collective. Individuals must have spaces in whi

En större mängd kvartsavslag och brända ben, upptäckta vid rekognosering (Norrbottens Museum) av hyggesberedda ytor norr om byn Sammakko, c. 40 km SO Gällivare, har tolkats att indikera ett kortvarigt använt boplatsområde. Platsen, liggande c. 100 meter norr Linaälven och i kanten av en nästan igenväxt göl, genomgick arkeologisk förundersökning sommaren 2019. Insamlat material av brända ben och trA large number of quartz fragments from knapping andburnt bone, discovered during reconnaissance (NorrbottensMuseum) of forest-cleared areas north of the villageSammakko, c. 40 km SE of Gällivare, have been interpretedto indicate a short-term used dwelling site. Th esite, located c. 100 meters north of the Linaälven Riverand at the edge of an almost overgrown pond, underwentarchaeological prelimin