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This report introduces the background and framing of the concept of mission portfolios, focusing on portfolios of actions. It describes portfolio management approaches, explaining the uses and benefits, as well as the challenges of applying a portfolio approach in mission implementation. Further, it presents several existing examples of portfolio approaches in practice at different levels of goverThis report introduces the background and framing of the concept of mission portfolios, focusing on portfolios of actions. It describes portfolio management approaches, explaining the uses and benefits, as well as the challenges of applying a portfolio approach in mission implementation. Further, it presents several existing examples of portfolio approaches in practice at different levels of gover

Relatively little is known about the relationship between socio-demographic factors and the chemical exposome in adolescent populations. This knowledge gap hampers global efforts to meet certain UN sustainability goals. The present work addresses this problem in Swedish adolescents by discerning patterns within the chemical exposome and identify demographic groups susceptible to heightened exposur

Peripheral nerves consist of delicate structures, including a rich microvascular system, that protect and nourish axons and associated Schwann cells. Nerves are sensitive to internal and external trauma, such as compression and stretching. Ulnar nerve entrapment, the second most prevalent nerve entrapment disorder after carpal tunnel syndrome, appears frequently at the elbow. Although often idiopa

This article shows how the Arctic landscapes in the Danish political drama series Borgen: Power & Glory demonstrate Greenland as a contested land in distinct ways: culturally due to the postcolonial tension between Denmark and Greenland; politically due to the conflicted interests from Denmark and other nations for the country’s natural resources; environmentally due to the looming transformat

Introduction: Fish β-parvalbumins are common targets of allergy-causing immunity. The nature of antibody responses to such allergens determines the biological outcome following exposure to fish. Specific epitopes on these allergens recognised by antibodies are incompletely characterised. Methods: High-content peptide microarrays offer a solution to the identification of linear epitopes recognised

Objectives The aim was to study the development of radiographic knee osteoarthritis (RKOA) in individuals with knee pain over 2 years, and the associations between radiographic changes and baseline variables. Design Longitudinal cohort study. Participants and setting This study is part of the Halland Osteoarthritis cohort. The included 178 individuals, aged 30-67, had knee pain, without cruciate l

En intellektuell funktionsnedsättning är en sårbarhetsfaktor förknippadmed diskriminering, stigmatisering och andra former avutsatthet. Att säkerställa att personer med intellektuell funktionsnedsättningfår sina intressen och rättigheter tillgodosedda i alla delar avrättssystemet är angeläget. Straffsystemet omfattar flera av samhälletsmest ingripande verktyg och gör anspråk på att fastställa skul

Background and aims: Obesity and type 2 diabetes are significant risk factors for atherosclerotic cardiovascular disease (CVD) worldwide, but the underlying pathophysiological links are poorly understood. Neurotensin (NT), a 13-amino-acid hormone peptide, facilitates intestinal fat absorption and contributes to obesity in mice fed a high-fat diet. Elevated levels of pro-NT (a stable NT precursor p

The Pythia8/Angantyr model for heavy ion collisions was recently updated with a mechanism for global colour reconnection. The colour reconnection model used is QCD colour algebra inspired and enhances baryon production due to the formation of string junctions. In this paper, we present updates to the junction formation and string fragmentation mechanisms, connected to heavy quark fragmentation. Th

Purpose: Traumatic brain injury is the main reason for the emergency department visit of up to 3% of the patients and a major worldwide cause for morbidity and mortality. Current emergency management guidelines recommend close attention to patients taking oral anticoagulation but not patients on antiplatelet therapy. Recent studies have begun to challenge this. The aim of this study was to determi

Here we present a new eastern Baltic Chironomidae training set (TS) containing 35 sites that was collected and merged with neighbouring published Finnish (82 lakes) and northern part of the Polish (nine lakes) TSs. Chironomidae, non-biting midges, are known to be strongly responsive to the July air temperature and are widely used to infer palaeotemperature. Several modern analogue-based TSs necess

The Sveconorwegian orogen in Scandinavia and the Grenville orogen in Canada are both remnants oflarge and hot orogens that formed part of the supercontinent Rodinia around 1 billion years ago. Formerly deeply buried portions of crust in these orogens are exposed and offer insights into the tectonic dynamics of the basement within large orogens. The Eastern Segment of the Sveconorwegian Province ho

Aims: Cognitive and perfusion changes have been previously observed in older men with Mini Mental State Examination scores>24 points. We aimed to investigate time change in cognitive domains in a cohort of non-demented men between age 68 and 82, and how they are expressed in regional defects estimated by Cerebral Blood Flow (rCBF). Methods: 103 men at age 81 with MMSE scores >24 (mean 28.4 ± 1.7),

The three-particle K-matrix, Kdf,3, is a scheme-dependent quantity that parametrizes short-range three-particle interactions in the relativistic-field-theory three-particle finite-volume formalism. In this work, we compute its value for systems of three pions in all isospin channels through next-to-leading order in Chiral Perturbation Theory, generalizing previous work done at maximum isospin. We

The 2024 editorial update of The Annals of Regional Science reaffirms the journal’s dedication to transparency and scholarly excellence in the field of regional science. Despite the challenges posed by the pandemic, the journal has demonstrated resilience and continued to serve as a pivotal platform for scholarly discourse. This update highlights the journal’s recent milestones, including changes

An analysis of an out-of-equilibrium cyclic reaction network which continuously converts a minor undesired product enantiomer to the desired major enantiomer by irreversible addition of chemical fuel and irreversible elimination of spent fuel is presented. The reaction network is maintained as long as fuel is added; interrupted fuel addition drives the system towards equilibrium, but the cyclic pr

We present positivity bounds, derived from the principles of analyticity, unitarity and crossing symmetry, that constrain the low-energy constants of chiral perturbation theory. Bounds are produced for 2, 3 or more flavours with equal meson masses, up to and including next-to-next-to-leading order (NNLO), using the second and higher derivatives of the amplitude. We enhance the bounds by using the

Impact melt rocks formed during hypervelocity impact events are ideal for studying impact structures. Here, we describe impact melt rock samples collected proximal to the 31 km wide 58 Ma Hiawatha impact structure, northwest Greenland, which is completely covered by the Greenland Ice Sheet. The melt rocks contain diagnostic shock indicators (e.g., planar deformation features [PDF] in quartz and sh