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BackgroundIt remains unclear as to why some individuals at low risk of cardiovascular disease (CVD) develop severe coronary atherosclerosis, while those at high CVD risk may remain free from coronary atherosclerosis.PurposeUsing Coronary Computed Tomography Angiography (CCTA), we aimed to identify factors associated with absence and severe coronary atherosclerosis in subjects from the general popu

Reconstructing critical-sized craniofacial bone defects is a global healthcare challenge. Current methods, like autologous bone transplantation, face limitations. Bone tissue engineering offers an alternative to autologous bone, with traditional approaches focusing on stimulating osteogenesis via the intramembranous ossification (IMO) pathway. However, IMO falls short in addressing larger defects,

Corrosion of steel components embedded in concrete is detrimental to the structural integrity and their intrinsic function,such as the leak-tightness of containment liners in nuclear reactor containment buildings. Detection of embedded linercorrosion is a challenging task due to the concrete’s heterogeneity and the large dimensions of containment buildings.This initial study explores early-stage d

Den växande efterfrågan på hållbar och miljövänlig elproduktion, tillsammans med globala osäkerheter, understryker behovet för nationer att uppnå självförsörjande produktion av el. Kärnkraft, som står för cirka 30% av Sveriges elproduktion, spelar en avgörande roll i att leverera fossilfri el. Eftersom många kärnkraftverk närmar sig slutet av sin planerade livslängd är det avgörande att förlänga dThe growing demand for sustainable electricity production, coupled with global uncertainties, highlights the need for nations to achieve self-sufficiency in producing electricity. Nuclear power, which provides around 30% of Sweden's electricity, plays a critical role in delivering fossil-free electricity. As many nuclear plants are near the end of their designated lifespans, extending their operat

Common wall lizards (Podarcis muralis) in Italy show a striking variation in body coloration across the landscape, with highly exaggerated black and green colors in hot and dry climates and brown and white colors in cool and wet climates. Males are more intensely colored than females, and previous work has suggested that the maintenance of variation in coloration across the landscape reflects clim

Purpose: To describe a novel technique for optimal orientation and accurate deployment of aortic endografts during complex endovascular aortic repair (cEVAR). Technique: After establishing the femoral access in the standard fashion, a long large-bore dilator is inserted before the cEVAR delivery system. The dilator is advanced beyond the renovisceral segment noticing the degree of axial rotation.

Forest Canopy Height (FCH) is a crucial parameter that offers valuable insights into forest structure. Spaceborne LiDAR missions provide accurate FCH measurements, but a significant challenge is their point-based measurements lacking spatial continuity. This study integrated ICESat-2’s ATL08-derived FCH values with multi-temporal and multi-source remote sensing (RS) datasets to generate continuous

Objective: To examine cardiovascular risk factors in 40-year-old participants in the health screening program targeted health dialogues (THDs). Design: Cross-sectional study. Setting: 99 Swedish healthcare centers. Intervention: Metabolic risk factors and health behaviors were assessed. THDs were provided. Subjects: 1831 (62.3%) THD participants that consented to take part in the research project.

Ongoing climate variability and change are increasing the burden of diarrhoeal disease worldwide. Meaningful early warning systems with adequate lead times (weeks to months) are needed to guide public health decision–making and enhance community resilience against health threats posed by climate change. Toward this goal, we trained various machine-learning models to predict diarrhoeal disease rate

Heatwaves are the deadliest weather hazard and people and societies across the world continue to suffer from heat-related impacts. Future climate projections show a troubling increase in cross-sectoral impacts including health and economic risk presented by heatwaves. Many weather hazards such as floods and droughts already have a type of Early Warning System (EWS) or Global Alert System, but a gl

The notion of error plays an important role, this article argues, in Per Olov Enquist’s ground-breaking documentary novel Legionärerna (The Legionnaires) (1968), which depicts the controversial Swedish extradition of Baltic soldiers in January 1946. In terms of the plot (re)constructed by Enquist, Swedish politicians and Baltic soldiers as well as the novel’s investigator, a kind of alter ego of t

Om drottning Kristina.

Neuroblastoma (NB) is one of the most lethal childhood cancers due to its propensity to become treatment resistant. By spatial mapping of subclone geographies before and after chemotherapy across 89 tumor regions from 12 NBs, we find that densely packed territories of closely related subclones present at diagnosis are replaced under effective treatment by islands of distantly related survivor subc

BackgroundUnderstanding the heterogeneity of opioid overdose fatalities is critical to developing effective preventive interventions. This study examines patterns of care contacts among people who subsequently died from opioid overdose. The aim was to identify distinct groups of deceased individuals, based on their contacts with different care agencies in their last year of life.MethodsA retrospec

Andelen engelskspråkig undervisning och kurslitteratur ökar hela tiden på svenska universitet och högskolor. Men det finns mycket lite stöd för att det skulle gynna kvaliteten på utbildningen. Däremot finns det gott om forskning som indikerar motsatsen.

Lärarna underpresterar och studenternas lärande försämras. Så blir det när undervisningen sker på ett språk som varken är lärarnas eller studenternas modersmål, skriver förläggaren Ola Håkansson och forskaren Peter Svensson.

BACKGROUND: Accumulating studies reported that several phosphodiesterases (PDEs) inhibitors might have cardiovascular benefits.OBJECTIVES: This study aimed to explore the relationship between genetically-predicted PDEs and ischemia heart disease via drug target Mendelian randomization (MR) approach, and then examine the effect of inhibitors of identified target on the outcomes by using real-world

Om Vilhelm av Ruysbroeck.