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Background: There is a lack of studies of amyotrophic lateral sclerosis (ALS) in immigrants. Objective: The objective is to study the association between country of birth and incident ALS in first-generation immigrants versus Swedish-born individuals, and in second-generation immigrants versus native Swedes. Methods: Study populations included all adults aged 18 years and older in Sweden, in the f
Purpose: Irritant contact dermatitis (ICD) is a major cause of occupational disease. The aim was to review the relation between exposure to occupational irritants and ICD and the prognosis of ICD. Methods: Through a systematic search, 1516 titles were identified, and 48 studies were included in the systematic review. Results: We found that the evidence for an association between ICD and occupation
Background: Compression of the greater occipital nerve (GON) may contribute to chronic headache, neck pain, and migraine in a subset of patients. We aimed to evaluate whether GON decompression could reduce pain and improve quality of life in patients with occipital neuralgia and chronic headache and neck pain. Methods: In this retrospective cohort study, selected patients with neck pain and headac
Motivated by the influence of deformation-induced microcracks on the effective electrical properties at the macroscale, an electro-mechanically coupled computational multiscale formulation for electrical conductors is proposed. The formulation accounts for finite deformation processes and is a direct extension of the fundamental theoretical developments presented by Kaiser and Menzel (Arch Appl Me
The concept of optic flow, a global pattern of visual motion that is both caused by and signals self-motion, is canonically ascribed to James Gibson's 1950 book "The Perception of the Visual World." There have, however, been several other developments of this concept, chiefly by Gwilym Grindley and Edward Calvert. Based on rarely referenced scientific literature and archival research, this article
När elsparkcyklar ersätter resor med till exempel bil och taxi bidrar de till att minska utsläppen och miljöpåverkan blir mindre. Om elsparkcyklarna däremot ersätter promenader eller resor med cykel och kollektivtrafik blir miljöpåverkan istället större.
As biological surfactants, bile salts (BSs), play important roles in biological processes, i.e., food digestion, but also in BS-related diseases, as well as in applications. In this thesis, the main focus was to gain a fundamental understanding of the intermolecular interactions between BSs and cationic block copolymers with the purpose of developing new BS sequestrants that are used in the treatm
Objective: The purpose of the study was to examine associations between self-esteem and symptoms of anxiety and depression among young adults who lost a parent to cancer. Methods: Older adolescents and young adults, aged 16 to 28 years, who had lost their parent to cancer and had accepted an invitation to join a support group, completed a questionnaire 5 to 8 months after the loss and a similar qu
In this article, we study microscopic properties of a two-dimensional Coulomb gas ensemble near a conical singularity arising from insertion of a point charge in the bulk of the droplet. In the determinantal case, we characterize all rotationally symmetric scaling limits (“Mittag-Leffler fields”) and obtain universality of them when the underlying potential is algebraic. Applications include a cen
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Peirce's best idea, and the one least implemented by himself and his followers, is that of an ethics of terminology. Using this ethics as a tool, we suggest that many Peircean terms are in fact misleading, or, as he said himself at the end of his life, "injurious."From the point of view of cognitive semiotics, there is no reason to abide by Peirce's definition of semiosis, but, taking up the two q
This thesis is ta study of the intersection between dark green spirituality and the green movement in relation to climate change and ecological crisis, and it explores how some ecologically concerned people try to orientate themselves in facing the challenges and especially the role of spirituality in this context. The study is set in the period 2009–2015, and it is based in fieldwork conducted i
Identification of a single molecular trait that is determinant of common malignancies may serve as a powerful diagnostic supplement to cancer type-specific markers. Here, we report a DNA methylation mark that is characteristic of seven studied malignancies, namely cancers of lung, breast, prostate, pancreas, colorectum, glioblastoma and B cell chronic lymphocytic leukaemia (CLL) (n = 137). This ma
Introduction: Dysfunction of immunoglobulins (Igs) has been detected in association with antiepileptic drugs (AEDs) and in newly diagnosed epilepsy patients. The aim of this study was to evaluate the effect of clinical features and the current or past use of AEDs on serum Ig concentrations in a well-examined group of patients with refractory epilepsy. Patients and methods: Using a nephelometric me
DNA methylation patterns have been recognised as cancer-specific markers with high potential for clinical applications. We aimed at identifying methylation variations that differentiate between breast cancers and other breast tissue entities to establish a signature for diagnosis. Candidate genomic loci were analysed in 117 fresh-frozen breast specimens, which included cancer, benign and normal br
Background: Lead-time is defined as the time by which screening advances the diagnosis compared with absence of screening. A sufficiently long lead-time needs to be achieved so that cancer can be detected while still curable. A very short lead-time may indicate poor sensitivity of the screening test, while a very long lead-time suggests overdiagnosis. Material and methods: In the first screening r
