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The association between the number of oocytes retrieved for IVF, perinatal outcome and obstetric complications

STUDY QUESTION: Is there an association between the number of oocytes retrieved for IVF, and perinatal and obstetric outcomes? SUMMARY ANSWER: No significant association was found between the number of oocytes retrieved and perinatal outcomes, while an association was found for placenta praevia and male gender. WHAT IS KNOWN ALREADY: Previous studies have shown that between 6 and 15 oocytes retrie

Associations of Circulating Protein Levels With Lipid Fractions in the General Population

Objective- Revealing patterns of associations between circulating protein and lipid levels could improve biological understanding of cardiovascular disease (CVD). In this study, we investigated the associations between proteins related to CVD and triglyceride (TG), total cholesterol, LDL (low-density lipoprotein), and HDL (high-density lipoprotein) cholesterol levels in individuals from the genera

Science audited: Indicator-based systems for research evaluation and resource allocation

This paper presents an ongoing research project investigating the use of bibliometrics for research evaluation and resource allocation purposes, and to investigate the effects of these evaluation models on individual, organizational and political levels. A main focus has been on bibliometrics based evaluation practices. The use of bibliometrics for local resource allocation at Swedish universities

Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes : A longitudinal population-based study in Finland

Objective To evaluate if obstructive sleep apnoea (OSA) modifies the risk of coronary heart disease, type 2 diabetes (T2D) and diabetic complications in a gender-specific fashion. Design and setting A longitudinal population-based study with up to 25-year follow-up data on 36 963 individuals (>500 000 person years) from three population-based cohorts: the FINRISK study, the Health 2000 Cohort Stud

Cardiac magnetic resonance evaluation of the extent of myocardial injury in patients with inferior ST elevation myocardial infarction and concomitant ST depression in leads V1-V3 : Analysis from the MITOCARE Study

The aim of our study was to examine the pathophysiology of ST depression (STD) in leads V1-V3 in the setting of inferior ST elevation myocardial infarction (iSTEMI) through the perspective of cardiac magnetic resonance (CMR). Methods: Differences in myocardial area at risk (MaR), infarct size, ejection fraction and myocardial segment involvement by CMR were compared in MITOCARE trial patients with

Temporal and depth variation of water quality due to thermal stratification in Karkheh Reservoir, Iran

Study region: Karkheh Dam Reservoir (KDR) located in western Iran. Study focus: To date, there has been no research in the KDR that investigates the interconnections among thermal stratification (ThS), water quality, and nutrients, based on field measurements. This study explored the temporal trend of ThS in the KDR and its interrelationship with water quality parameters based on data measured fro

Sharing data for future research—engaging participants’ views about data governance beyond the original project : a DIRECT Study

Purpose: Biomedical data governance strategies should ensure that data are collected, stored, and used ethically and lawfully. However, research participants’ preferences for how data should be governed is least studied. The Diabetes Research on Patient Stratification (DIRECT) project collected substantial amounts of health and genetic information from patients at risk of, and with type II diabete

Academic Achievement and Drug Abuse Risk Assessed Using Instrumental Variable Analysis and Co-relative Designs

Importance: Low academic achievement (AA) in childhood and adolescence is associated with increased substance use. Empirical evidence, using longitudinal epidemiologic data, may provide support for interventions to improve AA as a means to reduce risk of drug abuse (DA). Objective: To clarify the nature of the association between adolescent AA and risk of DA by using instrumental variable and co-r

Prostate cancer survivors : Risk and mortality in second primary cancers

To assess etiological and clinical consequences of second primary cancers (SPCs) in prostate cancer (PC) patients, we followed newly diagnosed patients to identify men who were diagnosed with a SPC and recorded their causes of death. We used the Swedish Family-Cancer Database to assess relative risks (RRs) and causes of death in SPCs until the year 2015 in patients with a PC diagnosis between 2001

Leptospira interrogans outer membrane protein lipl21 is a potent inhibitor of neutrophil myeloperoxidase

Leptospirosis is a widespread zoonotic and neglected infectious disease of human and veterinary concern that is caused by pathogenic Leptospira species. After entrance in the host, pathogenic leptospires evade the host natural defense mechanisms in order to propagate and disseminate to multiple organs. Myeloperoxidase is an enzyme stored in neutrophils azurophilic granules, and is released upon ne

The importance of institutions and policy settings for car sharing – Evidence from the UK, Israel, Sweden and Finland

The rapid growth of cities requires effective management of transport demand and restructuring of transport systems to address the needs of growing urban populations in an environmentally, socially and economically sustainable way. In recent years, car sharing has emerged as an alternative to owning cars in cities, which has potential to bring environmental gains and address social considerations.

Understanding climate resilience in Ghanaian cocoa communities – Advancing a biocultural perspective

This paper aims to contribute to the ongoing conceptual development and practical pursuit of resilience, the ability to absorb and respond to shocks, in an agricultural and climate change context. It builds on work that aims to dissolve the nature-society dualism and naturalisation of power relations inherent in systems thinking by developing and extending a framework originally conceived to integ