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OBJECTIVE: To develop a new chronic RA model which is driven by the innate immune system.METHOD: The injection of a cocktail of four monoclonal antibodies against collagen type II followed by intra-peritoneal injections of mannan (from Saccharomyces cerevisiae) on days 5 and 60 led to the development of chronic arthritis in B10.Q mice. The role of the innate versus the adaptive immune system in th

Purpose: This paper aims to demonstrate the relevance of identifying lock-ins that characterise a service, showing how lock-ins or impediments reinforce the status quo and prevent change. It provides an understanding of the factors hindering the development of value co-creation in this service. Design/methodology/approach: The study is based on 19 semi-structured interviews with representatives of

The aim of the work presented in this thesis was to improve the management ofinfections in immunocompromised patients by studying aspects of diagnostics,epidemiology and nosocomial transmission. Infection and rejection are commoncomplications in lung-transplant patients, and early diagnosis and treatment areimportant for a positive outcome. In a study of lung-transplant patients it wasfound that hThe aim of the work presented in this thesis was to improve the management of infections in immunocompromised patients by studying aspects of diagnostics, epidemiology and nosocomial transmission. Infection and rejection are common complications in lung-transplant patients, and early diagnosis and treatment are important for a positive outcome. In a study of lung-transplant patients it was found t

Purpose: The purpose of this paper is to analyse and discuss the potential of the service-dominant logic (SDL) as a tool for developing more effective public sector services in practice. Design/methodology/approach: One case concerning a public sector service organization has been studied – a contact centre in a Swedish municipality. The material consists of descriptions of managers’ and co-worker

The question of what makes ‘Nordic’ music distinctive is a matter of some dispute. Does it exist? Or, in what ways is it able to manifest itself? Like nationality, it is a construction of identity that emerges through discourses on music and on Nordicness. Essentially it is an open signifier, as concepts of Nordicness can be identified either with something dark, cold and obscure or as something r

Since N. v. the United Kingdom, an exceptionally high threshold has been applied to migrants who try to avoid expulsion in order to continue to receive medical assistance in the returning state. With Paposhvili v. Belgium, the Grand Chamber of the ECtHR recognized the ensuing protection gap and modified the standards. These modifications imply a small opening of the ‘very exceptional’ standard to

The issue of causation has been surprisingly overlooked in the area of international human rights law. The objective of this article is to fill this gap by investigating how the ECtHR finds causal connections between harm and state omissions within the framework of positive obligations. By engaging with causation, this article seeks to partially address the widely voiced concerns about the indeter

The Council of Europe Convention on Preventing and Combating Violence against Women and Domestic Violence (the Istanbul Convention) is a relatively recent treaty that has the objective to protect women against all forms of violence and to design a comprehensive framework of measures for achieving this aim. Migrant women are of special concern given the awareness that when their migration status is

The populist turn in national and international politics includes one common question across countries: curbing immigration and limiting the rights of migrants. In the light of these restrictive tendencies, the questions that this article seeks to address are: whether and how the European Convention on Human Rights (ECHR), as interpreted by the European Court of Human Rights (ECtHR), can be a poin