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Robust Localization of Close-Range Radar Reflections

In order to allow for a computationally efficient estimation of radar reflections, one commonly assumes the reflecting target to be in the far-field of the sensing array, such that the impinging wavefront is modeled as a linear phase-shift along the array. This works well in most radar scenarios, but causes significant performance degradation for close-range radar systems, wherein the curvature of

Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation

MMP12 is a metalloproteinase implicated in inflammation. To monitor its activity, we synthesized a membrane-targeted reporter (LaRee1) based on Foerster resonance energy transfer (FRET). Unlike existing sensors, LaRee1 detects MMP12 activity by loss of FRET plus internalization of the lipidated fragment. In bronchoalveolar lavages from a mouse model of pulmonary inflammation, LaRee1 detected MMP12

Is an Anti-Iran Alliance Emerging in the Middle East? : The Limits of Cooperation Between Israel and the Arab States

When Iran directed over 300 missiles and drones at Israel on April 13, Jordan helped fend off the attack. Initial media reports suggested that several other Arab states assisted in Israel’s defense, efforts they later denied. Nonetheless, a chorus of Israeli leaders, as well as some observers in Washington, interpreted these acts as a sign of a major shift. These Arab states, the argument went, wo

Health in Negotiation : Cultural Analytical Perspectives on Health and Inequalities in the Swedish Asylum Context

Health inequalities are a persistent and growing issue in different countries worldwide. Sweden, despite being one of the scandinavian countries with internationally recognized welfare system is no exception. The issue of health disparities and its increase among some groups, including those who are categorised as migrant have been acknowledged. Emergence of the COVID-19 pandemic, however, reveale

Aspects of Sex Differences in Type 1 Diabetes

Abstract:Background Type 1 diabetes (T1D) is one of the most common childhood autoimmune diseases, with rising incidence worldwide with a male predominance. The etiology behind the disease is mostly unknown and it is essential to understand the factors that impact its development to prevent the disease and personalize the treatment. This thesis aims to examine sex-specific differences in T1D, expl

The skåne emergency medicine (SEM) cohort

BACKGROUND: In the European Union alone, more than 100 million people present to the emergency department (ED) each year, and this has increased steadily year-on-year by 2-3%. Better patient management decisions have the potential to reduce ED crowding, the number of diagnostic tests, the use of inpatient beds, and healthcare costs.METHODS: We have established the Skåne Emergency Medicine (SEM) co

Complications in emergency department patients with acute coronary syndrome with contemporary care

INTRODUCTION: With the implementation of early reperfusion therapy, the number of complications in patients with acute coronary syndrome (ACS) has diminished significantly. However, ACS patients are still routinely admitted to units with high-level monitoring such as the coronary or intensive care unit (CCU/ICU). The cost of these admissions is high and there is often a shortage of beds. The aim o

A Microlevel Analysis of Danish Dairy Cooperatives: Opportunities for Large Data in Business History

We contribute to the argument for a “new” business history employing a quantitative approach. We illustrate opportunities for new perspectives from this approach using a novel microlevel longitudinal database comprising 131 variables for 1,419 cooperative creameries in Denmark for the period 1898–1945, which we also document and make available to the scholarly community. We present a number of app

A Provider-Facing Decision Support Tool for Prostate Cancer Screening in Primary Care : A Pilot Study

Our objective was to pilot test an electronic health record-embedded decision support tool to facilitate prostate-specific antigen (PSA) screening discussions in the primary care setting. Methods We pilot-tested a novel decision support tool that was used by 10 primary care physicians (PCPs) for 6 months, followed by a survey. The tool comprised (1) a risk-stratified algorithm, (2) a tool for faci

Digital Healthcare Platforms Enabling Remote Care Value Creation : The Patient Perspective

Remote care is a growing area in healthcare, due to fast technological development offering suitable equipment and platform for distant medical consultation and care. Remote care includes a promise towards care that has the potential to improve the patient's quality of life, prevent unnecessary reception visits, reduce costs, and enable timely and early therapeutic intervention in situations where

Palliative care services in paediatric oncology centres across Europe : A cross-sectional survey

Background: Palliative care (PC) is an integral part of cancer treatment. However, data on service availability is limited in childhood cancers. Aim: To describe the availability of PC services in paediatric oncology centres across Europe, and to identify barriers and facilitators for implementing and providing paediatric palliative care (PPC). Methods: Paediatric oncology centres across Europe we

A Laboratory of Stories : Teaching and Learning through Community Lore in the Contemporary Esoteric Society Sodalitas Rosae Crucis

This article develops the concept of community lore, initially devised by the social learning theorists Jean Lave and Etienne Wenger (1991). In extending this promising but hitherto neglected aspect of their work, this article sheds light on how and why community lore sustains and propels teaching and learning in the contemporary esoteric society Sodalitas Rosae Crucis (SRC). Ethnographic findings

Natur på skolgården för lärande, hälsa och hållbarhet

Gröna och artrika utemiljöer främjar barns och ungas välbefinnande och kunskap, bådegenom hälsofördelar kopplade till biologisk mångfald och genom att skapa förutsättningarför lek och lärande om natur och miljöfrågor. Skolgården skulle kunna bidra till allt detta,men är idag i hög grad en outnyttjad plats för biologisk mångfald och klimatanpassningav städer. I denna policy brief presenteras huvuds

Reconfiguring labour and welfare in the Global South : How the social question is framed as market participation

This special issue explores the intertwining reconfigurations of labour and welfare in the Global South by bringing together eight empirical studies of different national and transnational contexts and three commentaries. It asks how Global South people and states alike have come to prioritize market logics as guiding principles for welfare systems, moving away from collective risk-pooling towards

KRW Composition Theorems via Lifting

One of the major open problems in complexity theory is proving super-logarithmiclower bounds on the depth of circuits (i.e., P⊈NC1). Karchmer et al. (Comput Complex 5(3/4):191–204, 1995) suggested to approach thisproblem by proving that depth complexity behaves “as expected”with respect to the composition of functions f◊g. They showedthat the validity of this conjecture would imply that P⊈NC1.Seve

Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses

Conventional dendritic cells (cDC) play key roles in immune induction, but what drives their heterogeneity and functional specialization is still ill-defined. Here we show that cDC-specific deletion of the transcriptional repressor Bcl6 in mice alters the phenotype and transcriptome of cDC1 and cDC2, while their lineage identity is preserved. Bcl6-deficient cDC1 are diminished in the periphery but

A framework for business continuity management in a multiactor context

Business continuity management (BCM) is an analytic process capable of fostering the resilience of critical societal functions. While previous research on BCM primarily has focused on its applications within individual organizations, today's modern society involves networks of interdependent actors collectively delivering these essential functions to end users. This necessitates an expansion of BC

Temperature behavior of Ce3+ emission in (Lu,Y)2SiO5 single crystals excited by vacuum ultraviolet synchrotron light

Cerium doped (Lu,Y)2SiO5 (or LYSO) single crystals have been studied by means of luminescence excitation spectroscopy in the temperature range from 7 up to 300 K. Vacuum ultraviolet excitations in 4.5–8 eV energy range from synchrotron radiation of 1.5 GeV storage ring of MAX IV synchrotron facility. It is shown that both type of Ce3+ emission centers (seven and six coordinated centers) are excite