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Effect of current pulse duration in recovering quantitative induced polarization models from time-domain full-response and integral chargeability data
The signal level and shape of induced polarization responses are significantly affected by the current pulse duration and waveform. If not accounted for, this data dependency on the current will propagate trough the inversion to results rendering unquantifiable subsurface models. While this problem has been addressed in full-response induced polarization modelling, questions remain as to how to ac
Familial slipped capital femoral epiphysis
In 50 consecutive cases of slipped capital femoral epiphysis (SCFE) from 49 families, the heredity was analyzed by radiographic examination of the first-degree relatives and by interview regarding the second-degree relatives. In four of the 49 families, SCFE was obvious in one or more first-degree relatives; and in another 13 families (14 relatives), radiographic signs of SCFE were found besides t
Compensatory changes of in vivo acetylcholine and noradrenaline release in the hippocampus after partial deafferentation, as monitored by microdialysis
Lesions of the fimbria-fornix pathways are known to induce a partial cholinergic and noradrenergic denervation of the hippocampal formation, which is followed by a slow and protracted collateral sprouting by the spared afferents. Using the intracerebral microdialysis technique, compensatory changes in extracellular levels of acetylcholine (ACh) and noradrenaline (NA) have been monitored over time
Slipped capital femoral epiphysis in southern Sweden. Long-term results after femoral neck osteotomy
Opinions differ concerning the treatment of choice for severe slipped capital femoral epiphysis, probably due to the lack of long-term follow-up evaluations on the different methods of treatment. A series of 33 patients with severe slipped capital femoral epiphysis, treated per primam with wedge osteotomy of the femoral neck, were radiographically and clinically reexamined an average of 28 years (
Regulation of neurotrophin and trkA, trkB and trkC tyrosine kinase receptor messenger RNA expression in kindling
Levels of messenger RNA for nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and the tyrosine kinase receptors trkA, trkB and trkC have been studied using in situ hybridization in the rat brain 2 h and four weeks after kindling-induced seizures. Epileptiform activity evoked by hippocampal stimulation and exceeding 70 s lead to a concomitant and transient increase of brain- d
Longitudinal growth of the distal fibula in children with slipped capital femoral epiphysis
Summary: The longitudinal growth rates of the distal fibula were measured, using a roentgen stereophotogrammetric method, in 32 children treated for slipped capital femoral epiphysis and compared with growth rates in a series of normal children. The growth rates in patients were similar to the growth rates in normal children, in both boys and girls. However, at the time of slippage, 13 patients ha
Slipped capital femoral epiphysis in three generations
A male, his son, and grandson all had a slipped capital femoral epiphysis (physiolysis colli femoris - PCF). the importance of inheritance in PCF is discussed.
Vitality of the slipped capital femoral epiphysis : Preoperative evaluation by tetracycline labeling
In 25 cases with 29 slipped capital femoral epiphyses, treated with bilateral pinning, tetracycline was administrated preoperatively. Biopsies from the femoral head and the trochanteric region were analyzed by fluorescence microscopy. All had normal tetracycline labeling except the only patient with an acute severe slip.
Epidemiology of slipped capital femoral epiphysis in southern Sweden
Five hundred thirty-two cases of slipped capital femoral epiphysis (physiolysis colli femoris - PCF) treated at three orthopedic departments in southern Sweden between 1910 and 1982 were used for epidemiologic studies. Three hundred twenty-five cases came from a well-defined area and were used for incidence analyses. During the whole period of investigation, the disease was more common in men than
Distal respiratory tract viral infections in young children trigger a marked increase in alveolar mast cells
Viral infections predispose to the development of childhood asthma, a disease associated with increased lung mast cells (MCs). This study investigated whether viral lower respiratory tract infections (LRTIs) can already evoke a MC response during childhood. Lung tissue from young children who died following LRTIs were processed for immunohistochemical identification of MCs. Children who died from
Spatial learning impairments in rats with selective immunolesion of the forebrain cholinergic system
A monoclonal antibody to the low-affinity NGF receptor, 192 IgG, coupled to a cytotoxin, saporin, was recently introduced as an efficient selective neurotoxin for the NGFr-bearing cholinergic neurones in the rat basal forebrain. In the present study we report that an intracerebroventricular injection of this 192 IgG-saporin conjugate induces a severe, long-lasting spatial learning impairment, as a
Total hip replacement after nailing failure in femoral neck fractures
Forty patients were treated by means of total hip arthroplasty after nailing of femoral neck fractures had failed. Their average age was 73 years. Thirty-eight patients were still alive after 2 years and were reviewed. Two hips dislocated, but there was no early mortality. The results regarding pain, walking capacity, and function were good, and total hip replacement is considered to be the salvag
Correction by growth of rotational deformity after femoral fracture in children
Fourteen children with femoral shaft fractures were studied for 10 years after fracture or until growth plate closure, using repeated anteversion measurements. A mean anteversion difference of 9.6 degrees between the fractured and intact sides after fracture consolidation decreased to 5.6 degrees (p < 0.01), indicating that children have a considerable ability to correct a rotational deformity by
Acetylcholine release in the hippocampus : regulation by monoaminergic afferents as assessed by in vivo microdialysis
The role of monoamines in the functional regulation of the septo-hippocampal cholinergic system was studied using in vivo microdialysis of acetylcholine (ACh) release in the hippocampus of awake unrestrained rats. Systemic administration of the dopamine receptor agonist apomorphine (2.0 mg/kg) resulted in a 170% increase in hippocampal ACh overflow. Similarly the catecholamine-releasing agent amph
Intramedullary ender nailing combined with parham's modified band in the treatment of subtrochanteric femoral fractures* - Report of four cases
The treatment of oblique subtrochanteric femoral fractures is often difficult. Both fixation with a nail and plate, and intramedullary nailing have several pitfalls. Four cases treated with intramedullary Ender nailing combined with Parham modified bands are presented. The method is technically simple, gives complete reduction, allows early mobilization and gives a good functional result.
Behaviour-dependent changes in acetylcholine release in normal and graft-reinnervated hippocampus : evidence for host regulation of grafted cholinergic neurons
Grafted neurons obtained from the fetal basal forebrain can provide a functional cholinergic reinnervation of the hippocampal formation in rats with a lesion of the intrinsic septal cholinergic afferents. In the present experiments graft-derived acetylcholine release in the hippocampus was studied by microdialysis in awake rats during different types of behaviours which are known to activate the i
Hip displacement in relation to age and gross motor function in children with cerebral palsy
Purpose: Hip dislocation in cerebral palsy (CP) is a serious complication. By radiographic screening and prophylactic surgery of children at risk most dislocations can be prevented. CPUP, the Swedish CP registry and follow-up program, includes annual radiographic examinations of children at Gross Motor Function Classification System (GMFCS) levels III-V. Data from CPUP were analysed to assess the
Research highlights from the 2018 European Respiratory Society International Congress : airway disease
The annual European Respiratory Society (ERS) International Congress (held in Paris in 2018) was once again a platform for discussion of the highest-quality scientific research, cutting-edge techniques and innovative new therapies within the respiratory field. This article discusses only some of the high-quality research studies presented at this year's Congress, with a particular focus on airway
In vivo acetylcholine release as measured by microdialysis is unaltered in the hippocampus of cognitively impaired aged rats with degenerative changes in the basal forebrain
Acetylcholine (ACh) release was studied in awake, freely moving animals using in vivo microdialysis in the hippocampus of young (3-month-old) and aged (24-month-old) female Sprague-Dawley rats. Two groups of aged rats were selected on basis of their spatial learning performance in the Morris water maze: non-impaired aged rats which performed as well as the young control animals, and impaired aged
