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Improving methane production from wheat straw by digestate liquor recirculation in continuous stirred tank processes
Wheat straw is an abundant, cheap substrate that can be used for methane production. However, the nutrient content in straw is inadequate for methane fermentation. In this study, recycling digestate liquor was implemented in single-stage continuous stirred tank processes for enrichment of the nutrient content of straw with the aim of improving the methane production. The VS-based organic loading r
Tourism Place-making: Governance of Locality in Sweden
The presented argument comes from a frustration with the instrumental and de-contextualized view of tourism as a force of spatial change. Consequently, this article empirically illustrates the place-making agency of tourism by engaging with the mundane practicalities of producing geographical attractiveness. Place-making is investigated through four examples of destination developments with differ
Darriwilian (Middle Ordovician) delta C-13(carb) chemostratigraphy in the Precordillera of Argentina: Documentation of the middle Darriwilian Isotope Carbon Excursion (MDICE) and its use for intercontinental correlation
Although documented from Estonia, Latvia, Sweden, eastern North America, and China, the Middle Ordovician (Darriwilian) positive delta C-13 excursion known as the MDICE has previously not been recognized with certainty in South America. The most promising region in South America for detailed Middle Ordovician carbon isotope research is the Precordillera of western Argentina, where there are many e
The International Proteomics Tutorial Programme - reaching out to the next generation proteome scientists
One of the most critical functions of the various Proteomics organizations is the training of young scientists and the dissemination of information to the general scientific community. The education committees of the Human Proteome Organisation (HUPO) and the European Proteomics Association (EuPA) together with the other local proteomics associations are therefore launching a joint Tutorial Progra
Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse
In a randomized trial of therapy for FMS-like tyrosine kinase-3 (FLT3) mutant acute myeloid leukemia in first relapse, 224 patients received chemotherapy alone or followed by 80 mg of the FLT3 inhibitor lestaurtinib twice daily. Endpoints included complete remission or complete remission with incomplete platelet recovery (CR/CRp), overall survival, safety, and tolerability. Correlative studies inc
Reducing lower leg amputations in diabetes: a challenge for patients, healthcare providers and the healthcare system
Amputation of the lower limb is one of the most feared diabetic complications. It is associated with loss of mobility and a poor quality of life. Amputations result in high economic burden for the healthcare system. The financial cost is also high for patients and their families, particularly in countries that lack a comprehensive health service and/or have a low income. Losing a leg frequently im
Albitization and quartz dissolution in Paleoproterozoic metagranite, central Sweden - Implications for the disposal of spent nuclear fuel in a deep geological repository
Hydrothermal alteration resulting in albitization and quartz dissolution has been identified in Paleoproterozoic metagranites down to - 1000 m elevation at Forsmark, Sweden. The alteration features were discovered during investigations to locate a site for the disposal of spent nuclear fuel in a deep geological repository. In general, albitization occurs extensively, but it is also observed locall
Changes in synovial fluid and serum cytokines and ARGS-aggrecan, and urine CTX-II and NTX-I over five years after anterior cruciate ligament rupture: An exploratory analysis in the KANON trial.
Prospectively monitor levels of synovial fluid and serum pro-inflammatory cytokines and aggrecan ARGS neoepitope, and urine C-terminal type II (CTX-II) and N-terminal type I (NTX-I) collagen cross-linked telopeptides after acute anterior cruciate ligament (ACL) rupture.
Comparison between capillary, venous and arterial levels of protein S100B in patients with severe brain pathology
Background: Protein S100B is soon in clinical use as a sensitive marker after mild traumatic head injury in adults. Initial studies of S100B in pediatric head injury have shown promising results. Venous sampling can be challenging in children and capillary samples are often a preferred option. The aim of the study was to investigate the relation between capillary, venous and arterial measurements
Metabolic factors and blood cancers among 578,000 adults in the metabolic syndrome and cancer project (Me-Can)
We investigated associations between metabolic factors and blood cancer subtypes. Data on body mass index (BMI), blood pressure, blood glucose, total cholesterol, and triglycerides from seven prospective cohorts were pooled (n = 578,700; mean age = 44 years). Relative risks of blood cancers were calculated from Cox regression models. During mean follow-up of 12 years, 2,751 incident and 1,070 fata
Costs of care for people with dementia just before and after nursing home placement: primary data from eight European countries
Dementia is the most common cause of functional decline among elderly people and is associated with high costs of national healthcare in European countries. With increasing functional and cognitive decline, it is likely that many people suffering from dementia will receive institutional care in their lifetime. To delay entry to institutional care, many European countries invest in home and communi
Identification of a Novel, Recurrent HEY1-NCOA2 Fusion in Mesenchymal Chondrosarcoma Based on a Genome-Wide Screen of Exon-Level Expression Data
Regulation of advanced therapy medicinal products will affect the practice of haematopoietic SCT in the near future: a perspective from the EBMT cell-processing committee.
Further Insights into the Catalytical Properties of Deglycosylated Pyranose Dehydrogenase from Agaricus meleagris Recombinantly Expressed in Pichia pastoris
The present study focuses on fragmented deglycosylated pyranose dehydrogenase (fdgPDH) from Agaricus meleagris recombinantly expressed in Pichia pastoris. Fragmented deglycosylated PDH is formed from the deglycosylated enzyme (dgPDH) when it spontaneously loses a C-terminal fragment when stored in a buffer solution at 4 degrees C. The remaining larger fragment has a molecular weight of similar to
Inclusive gauge boson production in the color dipole formalism
The inclusive production of the gauge bosons W-+/- and Z(0) is studied within the color dipole formalism. Gluon saturation effects associated with nonlinear corrections to the QCD dynamics, which are expected to contribute at high energies, are naturally included in such formalism. We estimate the contribution of these effects at LHC energies and compare our results with the next-to-next-to-leadin
Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions
At least 17 genomic regions are established as harboring melanoma susceptibility variants, in most instances with genome-wide levels of significance and replication in independent samples. Based on genome-wide single nucleotide polymorphism (SNP) data augmented by imputation to the 1,000 Genomes reference panel, we have fine mapped these regions in over 5,000 individuals with melanoma (mainly from
Comparison of Asymptomatic Bacteriuria Escherichia coli Isolates from Healthy Individuals versus Those from Hospital Patients Shows that Long-Term Bladder Colonization Selects for Attenuated Virulence Phenotypes
Asymptomatic bacteriuria (ABU) is a condition where bacteria stably colonize the urinary tract, in a manner closely resembling commensalism at other mucosa! sites. The patients carry >10(5) CFU/ml for extended periods of time and rarely develop symptoms. Contrasting the properties of ABU strains to those of uropathogenic isolates causing symptomatic infection is therefore highly relevant to unders
Investigation of thermal radiation effects on solid oxide fuel cell performance by a comprehensive model
Thermal radiation in the air and fuel channels has the potential to dramatically influence the overall operating conditions and performance of solid oxide fuel cells. A 3D comprehensive model is developed, with emphasis on quantifying the radiative heat transfer process and its effects. The radiosity method is used for the thermal radiation in the air and fuel channels. The thermal radiation heat