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Development and Implementation of Cardiac Event Detectors in Digital CMOS

This doctoral dissertation presents the development and digital hardware realization of cardiac event detectors. Implantable medical appliances, as the cardiac pacemaker, have progressed from a life sustaining device to a device that considerably improves life quality for all ages. The number of electronic devices and household appliances in everyday live has an ongoing exponential growth. The

An Adaptive Root-Solving Controller for Tracking of Nonlinear Dynamic Plants

Adaptive tracking of nonlinear dynamic plants is currently an important area of research. The main difficulty being felt by the research community is the lack of a general modelling framework that can facilitate synthesis of a simplistic control law, while being capable of providing accurate approximation of nonlinear systems. In this study a novel technique based on the control-oriented U-model i

Neural Network Approaches To Survival Analysis

Popular Abstract in Swedish Denna avhandling behandlar artificiella neuron nätverk och deras applikation inom medicin. Den utgår ifrån att det är viktigt att kunna uppskatta en patients överlevnadschanser för att kunna erbjuda rätt behandling för olika former av cancer. Generellt kan man säga att ju värre prognos desto mer omfattande behandling behöver man sätta in. Vissa patienter kan botas med ePredicting the probable survival for a patient can be very challenging for many diseases. In many forms of cancer, the choice of treatment can be directly impacted by the estimated risk for the patient. This thesis explores different methods to predict the patient's survival chances using artificial neural networks (ANN). ANN is a machine learning technique inspired by how neurons in the brain fu

Aktuella behandlingsprinciper vid pseudocystor i pankreas. Ultraljud och datortomografi har revolutionerat handläggningen

Pancreatic pseudocysts often complicate the course of both acute and chronic pancreatitis. The management, if the pseudocysts are symptomatic, still remains a substantial clinical problem. Surgical drainage was prior to the introduction of ultrasound and CT more or less the treatment of choice. A vide variety of other treatments have, however, been described that aim to achieve at least as good sh

MORAXELLA CATARRHALIS OUTER MEMBRANE PROTEINS AND THEIR INTERACTIONS WITH THE HUMAN HOST

Moraxella catarrhalis is an airway pathogen whose role in infection has been increasingly recognized in recent years. Most authorities in this field now agree that M. catarrhalis causes significant morbidity and is not just a harmless commensal. The universal prevalence of BRO ?-lactamases in this pathogen is a serious concern. In addition, M. catarrhalis may be further propelled into a more promi

Development and psychometric testing of the Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS).

Background: The aim of this study was to develop and psychometrically test a short, patient-reported questionnaire to be used in clinical practice for patients with Irritable Bowel Syndrome (IBS). The Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS) questionnaire was designed to measure the treatment response of symptoms and well-being in patients suffering from IBS. Methods: The VAS-I

The potential of proton beam radiation therapy in prostate cancer, other urological cancers and gynaecological cancers

A group of Swedish oncologists and hospital physicists have estimated the number of patients in Sweden suitable for proton beam therapy. The estimations have been based on current statistics of tumour incidence, number of patients potentially eligible for radiation treatment, scientific support from clinical trials and model dose planning studies and knowledge of the dose-response relations of dif

Leaching of concrete : the leaching process and its effects

Popular Abstract in Swedish Avhandlingen presenterar en experimentell studie av urlakning av betong orsakat av vatten som tränger igenom betongen, eller av diffusion av joner till vatten på uppströmssidan. Urlakningsförloppet och dess effekter modelleras med finita-element-metoden.The present report presents an experimental study of leaching of concrete caused by water percolating through the concrete, or by diffusion from concrete to external water in contact. An apparatus was designed and constructed in which de-ionised water could be forced, by external pressure, through a number of concrete specimens of differing characteristics. It was found that, whereas the initial w