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Palaeoproterozoic reworking of early Archaean lithospheric blocks : Rocks and zircon records from charnockitoids in Volgo-Uralia

The Volgo-Uralia segment, which constitutes one fourth of the East European Craton, is covered by sedimentary deposits. From geophysical studies and examination of thousands of drillcores, Volgo-Uralia has been recognised as a vast high-grade terrain with a complex crustal history extending from the Palaeoarchaean to the Palaeoproterozoic. Our recent studies are focused on the search for the oldes

Digitally enabling sustainable food shopping : App glitches, practice conflicts, and digital failure

New digital food platforms are being launched accompanied with the promise of also promoting more sustainable food consumption. However, despite some success, many of these efforts to digitally reconfigure consumers food practices fail. The aim of this paper is to empirically explore, conceptualize and explain such failures. Taking a practice theory approach, and drawing on a field experiment usin

The Sharing Economy in Cities : Institutionalisation and Sustainability

The sharing economy is a novel way of distributing physical resources facilitated by online platforms where temporary access is given to goods owned by peers or organisations. It has become prominent in urban areas where a large accumulation of resources in close proximity and the ubiquity of information and communications technology enable it to grow. Its emergence has had various impacts on exis

Annual to decadal temperature adaptation of the soil bacterial community after translocation across an elevation gradient in the Andes

The response of soil microbial activity to climate warming has been predicted to have a large destabilising effect on the carbon cycle. However, the nature of this feedback remains poorly understood, especially in tropical ecosystems and across annual to decadal timescales. We studied the response of bacterial community growth to 2 and 11 years of altered temperature regimes, by translocating soil

Millennial-scale interaction between the East Asian winter monsoon and El Niño-related tropical Pacific precipitation in the Holocene

Both the East Asian winter monsoon (EAWM) and El Niño (EN) activities are vital climate modes that regulate the Pacific hydrologic cycle. However, the Holocene interactions among the EAWM, EN activities, and tropical Pacific precipitation remain unclear due to the lack of appropriate EAWM proxies. Here, we present high-resolution grain size records from the East China Sea shelf along with a transi

Proton reduction by phosphinidene-capped triiron clusters

Bis(phosphinidene)-capped triiron carbonyl clusters, including electron rich derivatives formed by substitution with chelating diphosphines, have been prepared and examined as proton reduction catalysts. Treatment of the known cluster [Fe3(CO)9(µ3-PPh)2] (1) with various diphosphines in refluxing THF (for 5, refluxing toluene) afforded the new clusters [Fe3(CO)7(µ3-PPh)2(κ2-dppb)] (2), [Fe3(CO)7(µ

Inter-laboratory comparison of gene expression biodosimetry for protracted radiation exposures as part of the RENEB and EURADOS WG10 2019 exercise

Large-scale radiation emergency scenarios involving protracted low dose rate radiation exposure (e.g. a hidden radioactive source in a train) necessitate the development of high throughput methods for providing rapid individual dose estimates. During the RENEB (Running the European Network of Biodosimetry) 2019 exercise, four EDTA-blood samples were exposed to an Iridium-192 source (1.36 TBq, Tech

Cardiovascular magnetic resonance in women with cardiovascular disease : position statement from the Society for Cardiovascular Magnetic Resonance (SCMR)

This document is a position statement from the Society for Cardiovascular Magnetic Resonance (SCMR) on recommendations for clinical utilization of cardiovascular magnetic resonance (CMR) in women with cardiovascular disease. The document was prepared by the SCMR Consensus Group on CMR Imaging for Female Patients with Cardiovascular Disease and endorsed by the SCMR Publications Committee and SCMR E

Area-selective Electron-beam induced deposition of Amorphous-BNx on graphene

Thin, stable and inert dielectric spacers are essential for manufacturing electronic devices based on 2D materials. However, direct synthesis on top of 2D materials is difficult due to their inert nature. In this work, we studied how an electron beam induces fragmentation of borazine and enables spatially confined synthesis of amorphous-BNx on graphene at room temperature. Using a combination of X

Extracellular vesicles in renal inflammatory and infectious diseases

Extracellular vesicles can mediate cell-to-cell communication, or relieve the parent cell of harmful substances, in order to maintain cellular integrity. The content of extracellular vesicles includes miRNAs, mRNAs, growth factors, complement factors, cytokines, chemokines and receptors. These may contribute to inflammatory and infectious diseases by the exposure or transfer of potent effectors th

Cross-term-compensated gradient waveform design for tensor-valued diffusion MRI

Diffusion MRI uses magnetic field gradients to sensitize the signal to the random motion of spins. In addition to the prescribed gradient waveforms, background field gradients contribute to the diffusion weighting and thereby cause an error in the measured signal and consequent parameterization. The most prominent contribution to the error comes from so-called ‘cross-terms.’ In this work we presen

Exploring biomarkers associated with deteriorating vascular health using a targeted proteomics chip : The SABPA study

ABSTRACT: In this observational study, by the use of a multiplex proteomic platform, we aimed to explore associations between 92 targeted proteins involved in cardiovascular disease and/or inflammation, and phenotypes of deteriorating vascular health, with regards to ethnicity.Proteomic profiling (92 proteins) was carried out in 362 participants from the Sympathetic activity and Ambulatory Blood P

Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries

Importance Tracheal intubation is one of the most commonly performed and high-risk interventions in critically ill patients. Limited information is available on adverse peri-intubation events.Objective To evaluate the incidence and nature of adverse peri-intubation events and to assess current practice of intubation in critically ill patients.Design, Setting, and Participants The International Obs

Reflections on the Enforcement of Labour Law : A Review of Re-inventing Labour Law Enforcement. A Socio-Legal Analysis by Louise Munkholm, Hart 2020

‘… technical law by itself is useless, at best an arid game played by keen minds in courtrooms and academic ivory towers. To understand its significance we must look at its historical and social setting'. (K. W. Wedderburn, The Worker and the Law 7 (Penguin Books 1965)). ‘… ultimately the point of labour law is to do something'. (Hugh Collins, Gillian Lester & Virginia Mantouvalou, Introductio

Rational Enzyme Design without Structural Knowledge : A Sequence-Based Approach for Efficient Generation of Transglycosylases

Glycobiology is dogged by the relative scarcity of synthetic, defined oligosaccharides. Enzyme-catalysed glycosylation using glycoside hydrolases is feasible but is hampered by the innate hydrolytic activity of these enzymes. Protein engineering is useful to remedy this, but it usually requires prior structural knowledge of the target enzyme, and/or relies on extensive, time-consuming screening an