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Working towards paradise; an interdisciplinary theoretical framework for environmental peacebuilding

Exploring the human-environment nexus and linkages between (post-conflict) political developments and environmental dimensions, this paper reflects on the development of interdisciplinary theories of environmental peacebuilding. Theories of environmental peacebuilding come from a variety of different disciplines within the social and biophysical sciences; warfare ecology (Machlis et al. , 2011), e

Every day peace: the ignored role of Civil Society in the Syrian Uprising

This paper discusses the role of civil society in the Syrian war between 2012 and 2016, specifically in the so-called "liberated areas" under the control of the Free Syrian Army and the Syrian opposition. A postdoctoral research project of Copenhagen University between 2014 and 2016, has investigated the role of citizen video journalists and peaceful activists in the Syrian uprisings. Responding t

Occupational exposure to organic solvents and risk of male breast cancer : A European multicenter case-control study

Objectives The etiology of male breast cancer (MBC) is largely unknown but a causal role of exposure to organic solvents has been suggested. Previous studies on occupational risk factors of breast cancer were often restricted to women who are frequently exposed to lower levels and at a lower frequency than men. We investigated the association between MBC and occupational exposure to petroleum and

A multi-omic study reveals BTG2 as a reliable prognostic marker for early-stage non-small cell lung cancer

B-cell translocation gene 2 (BTG2) is a tumour suppressor protein known to be downregulated in several types of cancer. In this study, we investigated a potential role for BTG2 in early-stage non-small cell lung cancer (NSCLC) survival. We analysed BTG2 methylation data from 1230 early-stage NSCLC patients from five international cohorts, as well as gene expression data from 3038 lung cancer cases

Waste policies gone soft : An analysis of European and Swedish waste prevention plans

This paper presents an analysis of European and Swedish national and municipal waste prevention plans to determine their capability of preventing the generation of waste. An analysis of the stated objectives in these waste prevention plans and the measures they propose to realize them exposes six problematic features: (1) These plans ignore what drives waste generation, such as consumption, and (2

Striking difference in response to expanding brood parasites by birds in western and eastern Beringia

Two species of obligate brood-parasitic Cuculus cuckoos are expanding their ranges in Beringia. Both now breed on the Asian side, close to the Bering Strait, and are found in Alaska during the breeding season. From May to July 2017, we used painted 3D-printed model eggs of two cuckoo host-races breeding in northeastern Siberia to test behavioral responses of native songbirds on both sides of the B

« For the women » - In Memoriam Simone Veil (1927-2017)

This In Memoriam presents the life of Simone Veil, an influential French politician, remembered for a law that made abortion legal in 1974. Simone Veil's contribution to the rights of women is featured as an instance of parrhesia (Foucault, 2011) that was able to establish a new regime of truth about the body, sexuality, and reproductive capacities of French women.

Reinforcement Learning for 4-Finger-Gripper Manipulation

In the framework of robotics, Reinforcement Learning (RL) deals with the learning of a task by the robot itself. This paper presents a hierarchical planning approach in which the robot learns the optimal behavior for different levels. For high-level discrete actions, Q-learning was chosen, whereas for the low level we utilize Policy Improvement with Path Integrals (PI^2) algorithm to learn the par

Soft X-ray Spectroscopy as a Probe for Gas-Phase Protein Structure : Electron Impact Ionization from Within

Preservation of protein conformation upon transfer into the gas phase is key for structure determination of free single molecules, for example using X-ray free-electron lasers. In the gas phase, the helicity of melittin decreases strongly as the protein's protonation state increases. We demonstrate the sensitivity of soft X-ray spectroscopy to the gas-phase structure of melittin cations ([melittin

Has aerobic exercise effect on pain perception in persons with migraine and coexisting tension-type headache and neck pain? A randomized, controlled, clinical trial

Background: A large subset of persons with migraine suffers from coexisting tension-type headache and neck pain which may adversely affect the prognosis of migraine. Aerobic exercise has been shown to decrease migraine burden in these persons. Therefore, the aim of this study was to investigate whether the effect of aerobic exercise in persons with migraine and coexisting tension-type headache and

Family adjustment to diabetes diagnosis in children : Can participation in a study on type 1 diabetes genetic risk be helpful?

Background: Diagnosis of type 1 diabetes often causes a negative psychological impact on families. We examined whether parents and children enrolled in The Environmental Determinants of Diabetes in the Young (TEDDY) study differ in their psychological adjustment to diabetes diagnosis compared to children diagnosed with diabetes in the community. Methods: TEDDY follows 8676 children at genetic risk

Pharmacokinetic modelling and validation of the half-life extension needed to reduce the burden of infusions compared with standard factor VIII

Introduction: Currently, no universally accepted definition of extended half-life (EHL) recombinant FVIII (rFVIII) exists. Identifying the minimum half-life extension ratio required for a reduction in dosing frequency compared with standard rFVIII could enable a more practical approach to decisions around prophylaxis with EHL rFVIII. Aim: To identify the half-life extension ratio required to decre

Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial

Aim: Metformin is the first-line treatment for Type 2 diabetes. However, not all people benefit from this drug. Our aim was to investigate the effects of metformin on the plasma metabolome and whether the pretreatment metabolite profile can predict HbA1c outcome. Methods: Post hoc analysis of the Copenhagen Insulin and Metformin Therapy (CIMT) trial, a multicentre study from May 2008 to December 2

Endocrine disruptors and testicular function

Despite concerns of the scientific community regarding the adverse effects of human exposure to exogenous man-made chemical substances or mixtures that interfere with normal hormonal balance, the so called “endocrine disruptors (EDs)”, their production has been increased during the last few decades. EDs' extensive use has been implicated in the increasing incidence of male reproductive disorders i

Identification and use of personalized genomic markers for monitoring circulating tumor DNA

Digital PCR techniques are ideally suited for accurately quantifying trace amounts of target DNA sequences, such as tumor-derived mutant DNA that is present in the blood circulation of patients with cancer. Here, we describe an approach marrying low-coverage whole-genome sequencing of tumor tissues, to enumerate chromosomal rearrangement breakpoints, together with droplet digital PCR (ddPCR)-based