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Bekämpningen av penningtvätt utgör ett centralt samhällsintresse inom Europeiska unionen och har gett upphov till ett omfattande regelverk som ställer långtgående krav på att verksamhetsutövare behandlar och lagrar personuppgifter. Samtidigt har skyddet för den personliga integriteten stärkts genom EU:s allmänna dataskyddsförordning (GDPR). Regelverken är inte direkt motstridiga, men förutsätter eThe fight against money laundering constitutes a central public interest within the European Union and has resulted in an extensive regulatory framework imposing far-reaching obligations on obliged entities to process and retain personal data. At the same time, the protection of personal privacy has been strengthened through the EU General Data Protection Regulation (GDPR). Although these regulato

Circulating levels of the astrocytic marker S100B have been associated with risk of neuropsychiatric or neurological disorders. However, reported effects have been inconsistent, and no causal relations have yet been established. We applied two-sample Mendelian Randomization (MR) on the association statistics from genome-wide association studies (GWAS) for circulating S100B levels measured 5-7 days

Background and purpose: Stereotactic radiosurgery (SRS) requires high positional accuracy to safely deliver large doses. This study evaluated an integrated surface- and image-guided radiotherapy (SGRT-IGRT) system by analysing (1) the agreement between thermo-optical and stereoscopic X-ray positioning, and (2) the impact of intra-fractional workflows on treatment accuracy and time. Materials and m

Background: Stereotactic body radiotherapy (SBRT) is an established treatment for previously unirradiated spinal metastases; however, the literature is limited with respect to SBRT as a re-irradiation salvage therapy. We performed a systematic review and meta-analysis as basis for joint ESTRO-ISRS clinical practice recommendations of salvage SBRT for spinal metastases. Methods: A systematic review

Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants remain inadequately understood. In this study, we report a genome-wide association study of HF and its subtypes in a sample of 1.9 million individuals. A total of 153,174 individual

Charged Higgs bosons produced either in top-quark decays or in association with a top quark, subsequently decaying via (Formula presented), are searched for in (Formula presented) of proton-proton collision data at (Formula presented) recorded with the ATLAS detector. Depending on whether the top quark is produced together with the (Formula presented) decays hadronically or semileptonically, the s

Inflammatory responses to acute stimuli are proposed to regulate sleep, but the relationship between chronic inflammation and habitual sleep duration is elusive. Here, we study this relation using genetically predicted level of chronic inflammation, indexed by CRP and IL6 signaling, and self-reported sleep duration. By Mendelian randomization analysis, we show that elevated CRP level within <10 mg

Microplastics and nanoplastics (MNPs) are ubiquitous environmental pollutants with increasing implications for human health. While their presence in human tissues is established, the molecular mechanisms driving their potential neurotoxicity remain unclear. This study investigates the impact of polystyrene (PS) on amyloid protein misfolding and cellular metabolism using Optical Photothermal Infrar

Top-quark pair production is observed in lead-lead ((Formula presented)) collisions at (Formula presented) at the Large Hadron Collider with the ATLAS detector. The data sample was recorded in 2015 and 2018, amounting to an integrated luminosity of (Formula presented). Events with exactly one electron and one muon and at least two jets are selected. Top-quark pair production is measured with an ob

Purpose: To illustrate the potential bias caused by imaging gradients in correlation MRI sequences using longitudinal magnetization storage (LS) and examine the case of filter exchange imaging (FEXI) yielding maps of the apparent exchange rate (AXR). Methods: The effects of imaging gradients in FEXI were observed on yeast cells. To analyze the AXR bias, signal evolution was calculated by applying

In 2022 and 2023, the Large Hadron Collider produced approximately two billion hadronic interactions each second from bunches of protons that collide at a rate of 40 MHz. The ATLAS trigger system is used to reduce this rate to a few kHz for recording. Selections based on hadronic jets, their energy, and event topology reduce the rate to Ô(10) kHz while maintaining high efficiencies for important s

ALICE is a large experiment at the CERN Large Hadron Collider. Located 52 meters underground, its detectors are suitable to measure muons produced by cosmic-ray interactions in the atmosphere. In this paper, the studies of the cosmic muons registered by ALICE during Run 2 (2015–2018) are described. The analysis is limited to multimuon events defined as events with more than four detected muons (Nµ

Using three independent archival sources, we previously documented substantial declines in stunting and wasting in Portugal during the mid-twentieth century. This note revisits the original evidence, clarifies the descriptive scope of our analysis, and situates the observed anthropo-metric changes within the broader evolution of public health, nutrition, and social policy in Portugal. We show that

OBJECTIVES: Nociception monitoring during general anesthesia is evolving to improve intraoperative management and postoperative outcomes. While opioid-based anesthesia (OBA) remains widely used for its strong antinociceptive effects, concerns about opioid-induced adverse effects have fueled interest in opioid-free anesthesia (OFA) approaches. This study aimed to compare perioperative and postopera

We document a substantial glass ceiling in the Swedish labor market: women constitute less than 20% within the top 1% of the earnings distribution. Using a structural micro-founded model of a dual earner household with learning-on-the-job, we link this to the child penalty. While on parental leave, women accumulate less human capital on the job, get promoted to a lesser extent, and hence are less

Among the headlines:Did the Directive trigger any other discussion in the area of CB? Shrinking share of workplace union clubs and union representativesCollective agreements on co-determination ‘light’Reduced co-determination and reduced working hoursProblems with labour law requirements in public procurementsBig enterprises in new industries resist collective agreements, but very few new collecti