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Enhanced contractility of intraparenchymal arterioles after global cerebral ischaemia in rat - new insights into the development of delayed cerebral hypoperfusion

Aim: Delayed cerebral hypoperfusion is a secondary complication found in the days after transient global cerebral ischaemia that worsens the ischaemic damage inflicted by the initial transient episode of global cerebral ischaemia. A recent study demonstrated increased cerebral vasoconstriction in the large arteries on the brain surface (pial arteries) after global cerebral ischaemia. However, smal

An Adaptive QR Decomposition Processor for Carrier Aggregated LTE-A in 28 nm FD-SOI

This paper presents an adaptive QR decomposition (QRD) processor for five-band carrier aggregated LTE-Adownlinks. The design uses time and frequency correlationproperties of wireless channels to reduce QRD computationswhile maintaining an uncoded bit error rate loss below 1 dB.An analysis on the performance of a linear interpolating QRD ispresented and optimum distances for different channel condi

Using machine learning to detect events in eye-tracking data

Event detection is a challenging stage in eye movement data analysis. A major drawback of current event detection methods is that parameters have to be adjusted based on eye movement data quality. Here we show that a fully automated classification of raw gaze samples as belonging to fixations, saccades, or other oculomotor events can be achieved using a machine-learning approach. Any already manua

Reconciling the dichotomy between developed and developing countries via universality in sustainable development goals : The case of Italy versus Bangladesh

The post-2015 developmental agenda and the SDGs have been formulated to advance holistic global progress and enable the adoption of quantitative targets for all countries by recognizing their respective national realities and capacities. This research examines how global ambitions can guide national policy formulation by selecting the Italian Republic and the People's Republic of Bangladesh as mod

Determination of dust deposition and associated nutrients in natural forest and plantation - A case study from the moist semi-deciduous forest zone in Ghana

Every year in December to February the dust laden Harmattan blows from Sahara towards southwest to the countries along the east west going coast of the Gulf of Guinea. Only few investigations have quantified external dust deposition in forests and plantations in that region and hereby the nutrient input by dust. This paper investigates three different methods for sampling and quantifying dust depo

Impact of the confinement on the intra-cage dynamics of molecular hydrogen in clathrate hydrates

We have studied the diffusive mobility of hydrogen molecules confined in different size cages in clathrate hydrates. In clathrate hydrate H2 molecules are effectively stored by confinement in two different size cages of the nano-porous host structure with accessible volumes of about 0.50 and 0.67 nm diameters, respectively. For the processes of sorption and desorption of the stored hydrogen the di

Climate warming and heat waves affect reproductive strategies and interactions between submerged macrophytes

Extreme climatic events, such as heat waves, are predicted to increase in frequency and intensity during the next hundred years, which may accelerate shifts in hydrological regimes and submerged macrophyte composition in freshwater ecosystems. Since macrophytes are profound components of aquatic systems, predicting their response to extreme climatic events is crucial for implementation of climate

Adaptive Baseband Pro cessing and Configurable Hardware for Wireless Communication

The world of information is literally at one’s fingertips, allowing access to previously unimaginable amounts of data, thanks to advances in wireless communication. The growing demand for high speed data has necessitated theuse of wider bandwidths, and wireless technologies such as Multiple-InputMultiple-Output (MIMO) have been adopted to increase spectral efficiency.These advanced communication t

Arbuscular mycorrhizal fungal community composition is altered by long-term litter removal but not litter addition in a lowland tropical forest

Tropical forest productivity is sustained by the cycling of nutrients through decomposing organic matter. Arbuscular mycorrhizal (AM) fungi play a key role in the nutrition of tropical trees, yet there has been little experimental investigation into the role of AM fungi in nutrient cycling via decomposing organic material in tropical forests. We evaluated the responses of AM fungi in a long-term l

On the Choice of Sampling Rates in Optimal Linear Systems

In a sample data system we are essentially restricted to control signals which are constant over the sampling interval. The purpose of this report is to analyze the effect of this restriction. The situation where the admissible control signals are piecewise continuous is used as a reference case and the problem is approached from a variational formulation of the control problem where the object of

Biomimetic spinning of artificial spider silk from a chimeric minispidroin

Herein we present a chimeric recombinant spider silk protein (spidroin) whose aqueous solubility equals that of native spider silk dope and a spinning device that is based solely on aqueous buffers, shear forces and lowered pH. The process recapitulates the complex molecular mechanisms that dictate native spider silk spinning and is highly efficient; spidroin from one liter of bacterial shake-flas

HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells

Background: Homeobox genes are master regulators of cell fate during embryonic development and their expression is altered in cancer. By regulating the balance between cell proliferation and differentiation, they maintain homeostasis of normal tissues. Here, we screened the expression of homeobox genes in mammary stem cells to establish their role in stem cells transformation in breast cancer. Met

Human activated protein C variants in a rat model of arterial thrombosis

BACKGROUND: Activated protein C (APC) inhibits coagulation by degrading activated factor V (FVa) and factor VIII (FVIIIa), protein S (PS) functioning as a cofactor to APC.METHODS: By mutagenesis of the vitamin K-dependent Gla domain of APC, we have recently created an APC variant having enhanced anticoagulant activity due to increased affinity for negatively charged phospholipid membranes. In the

Causal relations between knowledge-intensive business services and regional employment growth

Causal relations between knowledge-intensive business services and regional employment growth. Regional Studies. This paper studies the causal relations between regional employment growth in knowledge-intensive business services (KIBS) and overall regional employment growth using German labour-market data for 1999–2012. Adopting a recently developed technique, it uses a structural vector autoregre

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human traits(1), but these typically explain small fractions of phenotypic variation, raising questions about the use of further studies. Here, using 183,727 in

Dissatisfied patients after total knee arthroplasty.

Background and purpose - In 2003, an enquiry by the Swedish Knee Arthroplasty Register (SKAR) 2-7 years after total knee arthroplasty (TKA) revealed patients who were dissatisfied with the outcome of their surgery but who had not been revised. 6 years later, we examined the dissatisfied patients in one Swedish county and a matched group of very satisfied patients. Patients and methods - 118 TKAs i

Heparin-binding protein (HBP) in critically ill patients with influenza A (H1N1) infection

Heparin-binding protein (HBP) is an inducer of vascular endothelial leakage in severe infections. Fluid accumulation into alveoli is a general finding in acute respiratory distress syndrome (ARDS). Severe acute respiratory failure with ARDS is a complication of influenza A(H1N1) infection. Accordingly, we studied the HBP levels in critically ill patients with infection of influenza A(H1N1).Critica

School bullying and the mechanisms of moral disengagement

The aim of the present study was to examine to what degree different mechanisms of moral disengagement were related to age, gender, bullying, and defending among school children. Three hundred and seventy-two Swedish children ranging in age from 10 to 14 years completed a questionnaire. Findings revealed that boys expressed significantly higher levels of moral justification, euphemistic labeling,