Background: Type 2 diabetes, chronic kidney disease (CKD) and its cardiovascular complications are increasing as health problems worldwide. These diseases are interrelated with overlapping occurrence and once diabetes is established, the risk of cardiorenal disease is dramatically elevated. Thus, a search for unifying modifiable risk factors is key for effective prevention. Summary: Elevated fasti

Background: Obesity is suggested to underlie development of other metabolic aberrations, but longitudinal relationships between metabolic factors at various ages has not been studied in detail. Methods: Data from 27,379 men and 32,275 women with in total 122,940 health examinations in the Västerbotten Intervention Project, Sweden and the Vorarlberg Health Monitoring and Prevention Programme, Austr

To date, little is known about the effects of violence on the educational outcomes of adolescents in disadvantaged communities in South Africa. In response, self-report data were collected from a socioeconomically disadvantaged sample of 503 adolescents aged 10 to 18 participating in a child abuse prevention trial in the Eastern Cape. Adolescents were purposively selected in the trial. This study

IMPORTANCE Timing of surgical aortic valve replacement (SAVR) in patients with aortic valve stenosis and previous stroke for the risk of recurrent stroke is insufficiently investigated. OBJECTIVE To evaluate the association of time elapsed between previous stroke and SAVR with the risk of recurrent perioperative stroke, major adverse cardiovascular events (MACE), and mortality among patients with

A nonintrusive method for flow gas temperature measurement using differential optical absorption spectroscopy (DOAS) was demonstrated. A temperature-dependent spectra (TDS) originated from the DOAS spectra of sulfur dioxide (SO2) in the wavelength range of 276–310 nm was introduced, and the relationship between the TDS and the temperature was built through experimental calibration process. This re

Heme degradation by heme oxygenase enzymes is important for maintaining iron homeostasis and prevention of oxidative stress. Previous studies have reported that heme degradation proceeds through three consecutive steps of O2 activation: the regiospecific self-hydroxylation of heme, the conversion of hydroxyheme to verdoheme and CO, and the cleavage of the verdoheme macrocycle to release biliverdin

We report on the observation of backward-propagating 656-nm lasing of atomic hydrogen in flame using 205-nm femtosecond laser pulses. It shows a donut-shaped spatial mode and smooth temporal profile, suggesting spatially-resolved measurements in few-millimeters resolution.

We present measurements on a few cycle OPCPA laser chain where due to careful characterization and compensation of the spectral phase and spatio-temporal couplings, we are able achieve efficient HHG with very low pulse energy.

The wound environment is characterized by physiological pH changes. Proteolysis of thrombin by wound-derived proteases, such as neutrophil elastase, generates antimicrobial thrombin-derived C-terminal peptides (TCPs), such as HVF18 (HVFRLKKWIQKVIDQFGE). Presence of such TCPs in human wound fluids in vivo, as well as the occurrence of an evolutionarily conserved His residue in the primary amino aci

Objective: Systematic rehabilitation by geriatric interdisciplinary teams has been associated with favorable outcomes in frail older patients. The aim of the present meta-analysis was to evaluate the effects of interdisciplinary geriatric team rehabilitation in older patients with hip fracture. Design, setting, and participants: Randomized controlled trials involving participants sustaining hip fr

For patients with end-stage heart failure, the use of mechanical circulatory support has increased in the last decade due to improved outcomes with durable left ventricular assist devices. The management of these complex patients requires coordinated care by a multidisciplinary team including cardiac electrophysiologists because atrial and ventricular arrhythmias are prevalent in this population.

Objective: To systematically review the efficacy of psychological, pharmacological, and combined treatments for binge eating disorder (BED). Method: Systematic search and meta-analysis. Results: We found 45 unique studies with low/medium risk of bias, and moderate support for the efficacy of cognitive behavior therapy (CBT) and CBT guided selfhelp (with moderate quality of evidence), and modest su

This article explores the similarities between the two most successful Swedish films of the past years. Through a focus on the two elderly protagonists the article discusses how the films acknowledge challenges in these men’s lives and in both contemporary and past society, but effectively repackage any serious issue in a form that remains palatable to audiences in Sweden and internationally. Them

In this paper, InAs/GaSb nanowire tunnel field-effect transistors (TFETs) are studied theoretically and experimentally. A 2-band 1-D analytic tunneling model is used to calculate the on- and off-current levels of nanowire TFETs with staggered source/channel band alignment. Experimental results from lateral InAs/GaSb are shown, as well as first results on integration of vertical InAs/GaSb nanowire

A recent study of two successful energy transitions in Denmark and Germany shows that transparency and community participation are essential to drive the clean energy agenda forward at the local level.

Global warming and human land management have greatly influenced vegetation growth through both changes in spring phenology and photosynthetic primary production. This will presumably impact the velocity of vegetation greenup (Vgreenup, the daily rate of changes in vegetation productivity during greenup period), yet little is currently known about the spatio-temporal patterns of Vgreenup of global

We used eddy-covariance (EC) measurements of net ecosystem exchange (NEE) above canopy to assess the effects of thinning on CO2 fluxes at the ICOS Sweden site Norunda in central Sweden. This forest site consists of mixed pine and spruce stands approx. 100 years old. The thinning during late autumn 2008, performed in a semicircle from the mast extending 200m outwards harvested about 25% of the voluWe used eddy-covariance (EC) measurements of net ecosystem exchange (NEE) above canopy to assess the effects of thinning on CO2 fluxes at the ICOS Sweden site Norunda in central Sweden. This forest site consists of mixed pine and spruce stands approx. 100 years old. The thinning during late autumn 2008, performed in a semi-circle from the mast extending 200 m outwards harvested about 25% of the vo