Stakeholder involvement in strategic adaptation planning : Transdisciplinarity and co-production at stake?

To address increasing climatic variability and extremes, cities are gradually forced to develop climate change adaptation strategies that can ensure a continuous and transformative adaptation process. There is widespread consensus that the sustainable establishment of such strategies requires transdisciplinary approaches, that is, the involvement of internal and external stakeholders (state, civil

Mobile phones and the practice of shopping : A study of how young adults use smartphones to shop

The aim of this paper is to explore, illustrate and conceptualise how the introduction of mobile phones transforms the practice of shopping. Drawing on a focus group study of young adults and making use of Practice Theory, this paper shows that the introduction of mobile phones reconfigures the practice of shopping subsequently transforming the agency of consumers. Mobile phones enable consumers t

Alterations of striatal indirect pathway neurons precede motor deficits in two mouse models of Huntington's disease

Striatal neurons forming the indirect pathway (iSPNs) are particularly vulnerable in Huntington's disease (HD). In this study we set out to investigate morphological and physiological alterations of iSPNs in two mouse models of HD with relatively slow disease progression (long CAG repeat R6/2 and zQ175-KI). Both were crossed with a transgenic mouse line expressing eGFP in iSPNs. Using the open-fie

Fumarate decreases edema volume and improves functional outcome after experimental stroke

Background Oxidative stress and inflammation exacerbate tissue damage in the brain after ischemic stroke. Dimethyl-fumarate (DMF) and its metabolite monomethyl-fumarate (MMF) are known to stimulate anti-oxidant pathways and modulate inflammatory responses. Considering these dual effects of fumarates, we examined the effect of MMF treatment after ischemic stroke in mice. Methods Permanent middle ce

A novel endpoint for exacerbations in asthma to accelerate clinical development : A post-hoc analysis of randomised controlled trials

Background: Occurrence of severe asthma exacerbations are the cornerstone of the evaluation of asthma management, but severe asthma exacerbations are rare events. Therefore, trials that assess drug efficacy on exacerbations are done late in clinical development programmes. We aimed to establish an endpoint capturing clinically relevant deteriorations (diary events) that, when combined with severe

I Myself Am Only a Receiving Apparatus

Of Spirits and Empty Spaces

Maybe one must begin with som particular places : edited by Rodrigo Ortiz Monasterio and Yann Chanteigné Tytleman

Video capsule colonoscopy in routine clinical practice

Background: Colon capsule endoscopy (CCE) offers direct mucosal visualisation without sedation or gas insufflation required in conventional colonoscopy (CC). However, evidence for the role of CCE as an adjunct or alternative to CC remains equivocal. In this observational cohort study, we report our experience of using CCE to investigate patients with suspected colon pathology at a tertiary referra

Questionnaire

Where Everything Floats, interview with Lars Bang Larsen

Response to letter : "cortical bone area predicts incident fractures independently of areal bone mineral density in older men"

In the Face of Overwhelming Forces,

Dizziness, Navigating the Unknown

70 meisterwerke der samlung Verbund, Verbund, Vienna

Meeting Points 8: Both Sides of the Curtain,

Dit vindarna bär,

CPH:DOX, New Visions, screening

Good fortune, no blame - til minde om Emil Westman Hertz

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