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Hematopoietic Stem Cell Donors' Experiences of Information and Side-Effects During the First Year After Donation-A Swedish National Study

The aim was to describe hematopoietic stem cell (HSC) donors' experiences focusing on information and side effects during the first year after donation. Our prospective Swedish cohort study with adult HSC donors was performed from 2019 to 2022, with questionnaires at four time points from before until 12 months after donation. 173 unrelated and 68 related donors participated, and the majority dona

Double trouble! Concomitant distal ulna fractures predict worse 1-year outcome in distal radius fractures : a registry-based cohort study of 5,536 patients

BACKGROUND AND PURPOSE: Data on distal radius fractures (DRFs) with concomitant metaphyseal distal ulna fractures is limited. We aimed to determine whether a combined DRF and distal ulna fracture (DRUF) predicts a worse patient-reported outcome, measured by the Disabilities of the Arm, Shoulder, and Hand (DASH) score, 1 year after injury.METHODS: This prospective registry-based cohort study includ

Thermal effects on the dynamics of excitons in CsPb(Br1−xClx)3

The long-standing debate in the scientific community about whether ferroelectricity or ferroelasticity is the key property influencing the optoelectronic behavior of metal halide perovskites continues. In this study, we experimentally investigate the temperature dependence of photoluminescence from CsPb(Br1−xClx)3 nanowires and their heterojunctions. Our findings show an enhancement of the exciton

Hypoxic Burden is Associated with Cardiovascular Events : A Risk Stratification Analysis of the RICCADSA Cohort

BACKGROUND: The Apnea-Hypopnea Index (AHI), the standard measure of obstructive sleep apnea (OSA), has limitations in reflecting disease severity.RESEARCH QUESTION: Is high hypoxic burden (HB) more strongly associated with major cardiovascular and cerebrovascular adverse events (MACCEs) than AHI≥ 30/h?STUDY DESIGN AND METHODS: This secondary analysis of the RICCADSA observational cohort included 3

Development of Photoacoustic Imaging Techniques Towards Clinical Translation

This thesis encompasses an introductory part and five papers related to developing techniques and phantoms required for the further growth of photoacoustic imaging (PAI). In PAI, images are created by detecting acoustic waves followed by the absorption of laser light, enabling high spatial resolution while maintaining high optical contrast. Due to the distinct absorption patterns of various chromo

The Impact of the Parental Patterns of Morbidity and Comorbidity in the Cross-Generational Transmission of Risk for Major Depression and Alcohol Use Disorder

To further understand the inter-relationship of the familial transmission of major depression (MD) and alcohol use disorder (AUD), we examine, via a multivariable Cox proportional hazards model, risks for AUD and MD in 1,244,516 individuals born in Sweden from 1970 to 1990 to intact mother-father pairs as a function of parental diagnoses of MD and/or AUD. Across the nine possible mating types, we

Persistent Value Relations : Varieties and Explanation

Some things hold value in a way that makes them superior to others, regardless of how much of the lesser values are involved. Philosophers have often found this idea of persistent betterness to be puzzling. In this paper, we argue that superiority belongs to a broader class of persistent value relations, including stubborn varieties of equality and parity, each of which will be exemplified and ana

Humaniora i professionsutbildningar : Kunskap för komplexa yrken

Humaniora är ett viktigt – men ibland underskattat – vetenskapsområde som behövs för att utbilda studenter för en komplex yrkesvardag och för att möta aktuella samhällsutmaningar. Humanistisk kompetens ger förmåga att tolka, förstå och sätta kunskap i ett kulturellt, historiskt och samhälleligt sammanhang. Humaniora hjälper oss att navigera i komplexa frågor som inte enbart handlar om effektivitet

Grappling with the Climate Crisis in IR : Existentially, Psychologically, Interdisciplinarily

The introduction to this special issue argues that International Relations (IR) needs to give greater consideration to the existential and psychological implications of the accelerating climate crisis. Starting from debates about the disciplinary suitability of IR to meaningfully tackle an issue as all-encompassing as climate change, this introduction gives a short overview of how the problem of c

Megastigmanes isolated from Boehmeria nivea leaves and their immunomodulatory effect on IL-1β and IL-10 production in RAW264.7 macrophages

With the aim of isolating immunomodulatory compounds from the n-butanol extract of Boehmeria nivea leaves, nine megastigmane compounds were identified. Among these, the structure of the new compound 1, namely, “boehmegaside A”, was established using NMR and HR-ESI-MS, and its absolute configurations were established through ECD calculations and DP4+ analysis using DFT-NMR chemical shift calculatio

Associations of comorbid heart disease and depression/anxiety with multidimensional breathlessness in COPD – A cross-sectional study

Background: Comorbid conditions and breathlessness are associated with poor outcomes in chronic obstructive pulmonary disease (COPD). We evaluated the associations of comorbid heart disease and depression/anxiety with breathlessness in daily life among people with COPD. Methods: Cross-sectional analysis from the PRAXIS cohort in central Sweden. Data on patient characteristics and the modified Medi

A clinical study of efficacy and safety of the Carry Life UF system in continuous ambulatory peritoneal dialysis patients : protocol for a prospective, multicenter, randomized, crossover study

Background: Carry Life UF is a novel peritoneal dialysis (PD) technology for improved fluid management using steady concentration PD (SCPD). The Carry Life UF treatment starts with a manual peritoneal fill of 1.36% glucose PD fluid, followed by a 5-hour treatment where small amounts of glucose are continuously added to maintain a stable intraperitoneal glucose concentration. A recent in-center cli

The Studentification of Low-Wage Service Work in Sweden: Who Participates?

The study examines trends in part-time employment among school students (15–20 years old) in Sweden. Using data from the Swedish Labor Force Survey (2006–2019) and population-based registries, the article analyzes developments in employment rates and work patterns. The results indicate a rapid increase in part-time work, particularly in the hospitality sector, which underscores how young student-w

Examination of Anti-Inflammatory Effects After Propionate Supplementation in the R6/2 Mouse Model of Huntington’s Disease

Huntington’s disease is a progressive, untreatable neurodegenerative disorder caused by a mutation in the Huntingtin gene. Next to neurodegeneration, altered immune activation is involved in disease progression. Since central nervous system inflammation and dysfunction of immune cells are recognized as driving characteristics, immunomodulation might represent an additional therapeutic strategy. Sh

Beyond the Narratives of Experience and Money: The Formation of Teenage Students as Labor in Sweden

This article examines the formation of teenage students as workers through their participation in low-status service jobs, building on Weeks’ theorization of the contemporary work ethic. Based on 40 interviews with working teenagers in Sweden, the analysis explores how they use narratives of working to ‘gain experience’ and ‘earn extra money’ in response to the cultural imperative of constructing

Element Design for Active Learning : A Design Thinking Approach to Assignment Development for Political Science, Media, and Communication Education

Hundreds of active learning assignments are reported in the political education literature. However, the adaptability of these assignments to new courses can be limited by different learning outcomes, course themes, or institutional contexts. To assist educators in developing assignments that align with their teaching needs, this study introduces the concept of element design. Element design refer

Boron-Embedded Cluster Superlattices on Graphene on Ir(111)

Cluster superlattice membranes constitute a novel 2D material, comprising a cluster superlattice sandwiched between a graphene support and an amorphous carbon embedding matrix. They offer a platform for investigating phenomena at the few atom to small cluster level with lateral averaging techniques. The amorphous carbon matrix provides mechanical and thermal stability to the cluster array, but alt