WNT5A is a secreted signaling protein that promotes migration and invasion of oral squamous cell carcinoma (OSCC) cells through activation of non-canonical WNT signaling. Here, we examined expression of WNT5A, β-catenin, and E-cadherin by immunohistochemistry in 21 human diagnostic incision biopsies that each had regions of oral mucosa with a normal appearance adjacent to the affected tissue, dysp

A search for supersymmetry in events with large missing transverse momentum, jets, and at least one hadronically decaying tau lepton has been performed using 3.2 fb-1 of proton–proton collision data at s=13TeV recorded by the ATLAS detector at the Large Hadron Collider in 2015. Two exclusive final states are considered, with either exactly one or at least two tau leptons. No excess over the Standa

Mercury is a severe pollutant in China. A novel mobile laser spectroscopy laboratory was constructed and used in differential absorption lidar mapping in major Chinese cities, a heavily polluted mining area and an archeological site.

Heterogeneous catalysts for selective oxidation of C-H bonds were synthesized by co-polymerization of new N-heterocyclic carbene-palladium(II) (NHC-PdII) monomers with divinylbenzene. The polymer-supported NHC-PdII-catalysed undirected C-H acetoxylation of simple and methylated arenes as well as polyarenes, with similar or superior efficiency compared to their homogeneous analogues. In particular,

This book probes the relationship between Martin Heidegger and theology in light of the discovery of his Black Notebooks, which reveal that his privately held Antisemitism and anti-Christian sentiments were profoundly intertwined with his philosophical ideas. Heidegger himself was deeply influenced by both Catholic and Protestant theology. This prompts the question as to what extent Christian anti

During the last few years most work done on the task of image segmentation has been focused on deep learning and Convolutional Neural Networks (CNNs) in particular. CNNs are powerful for modeling complex connections between input and output data but lack the ability to directly model dependent output structures, for instance, enforcing properties such as smoothness and coherence. This drawback mot

A fully automatic system for abdominal organ segmentation is presented. As a first step, an organ localization is obtained via a robust and efficient feature registration method where the center of the organ is estimated together with a region of interest surrounding the center. Then, a convolutional neural network performing voxelwise classification is applied. The convolutional neural network co

Development of optical techniques in medical applications can be difficult due to limited access to realistic phantoms. Here a 3-D printed model based on CT-images of the thorax of an infant is developed and tested.

[NiFe] hydrogenases catalyse the reversible conversion of molecular hydrogen to protons and electrons. This seemingly simple reaction has attracted much attention because of the prospective use of H2 as a clean fuel. In this paper, we have studied how H2 binds to the active site of this enzyme. Combined quantum mechanical and molecular mechanics (QM/MM) optimisation was performed to obtain the geo

In this chapter, we describe the minigenome system for Ebola virus (EBOV), which reconstitutes EBOV polymerase activity in cells and can be used to model viral genome replication and transcription. This protocol comprises all steps including cell culture, plasmid preparation, transfection, and luciferase reporter assay readout.

The lack of a widely agreed framework to help define and align corporate brand identity constitutes a serious managerial problem and a shortcoming of the academic literature. In response, this article provides such a framework, the Corporate Brand Identity Matrix (CBIM), which draws upon the relevant literature, enriched by hands-on corporate experience gained by its application in three internati

In this chapter, we describe the detection of Ebola virus minigenomic mRNA using a nonradioactive Northern hybridization. This protocol comprises all steps beginning with the synthesis of a digoxigenin-labeled riboprobe, harvest of transcribed mRNA from cells transfected with the Ebola virus minigenome system, separation of mRNA species by denaturing RNA gel electrophoresis, transfer of the mRNA t

The Raheen Formation at Newtown Head in Waterford Harbour is a small isolated section of Ordovician rocks, dominated by volcanics of the Duncannon Group, but with interbedded fossiliferous shales. Although a brachiopod and trilobite dominated fauna has been known since the mid-nineteenth century, only the trilobites and cystoids have been assessed in modern terms. This paper describes the brachiop

The articles in this special issue contribute to the advances and development in the scholarship of brand orientation. They encompass a wide range of sub-topics, and collectively offer a unique insight into the still-emerging concept and new paradigm of brand orientation. In the process, they show how researchers across the world are contributing to the advancement of theory and practice. Our open

Grainyhead-like 2 is a human homolog of Drosophila grainyhead. It inhibits epithelial-to-mesenchymal transition that is necessary for cell migration, and it is involved in neural tube closure, epithelial morphogenesis, and barrier formation during embryogenesis by regulation of the expression of cell junction proteins such as E-cadherin and vimentin. Cancer shares many common characters with devel

On the role and function of brands. The first book on strategic brand management published in Swedish, and one of the first internationally. Brand management and trademark management is discussed. The notion of the brand is discussed and the the corporate brand and its role in modern business and society is introduced.