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BackgroundProenkephalin A 119-159 (PENK) is freely filtered in the glomerulus with plasma levels correlating with glomerular filtration rate. Therefore, PENK has been proposed as an early indicator of acute kidney injury (AKI) although its performance is dependent on the clinical setting. This meta-analysis aimed to investigate the correlation between PENK levels and the development of AKI.Methods

Low-coordinate surface sites, such as those present on high-index step edges, often exhibit chemical reactivity that markedly differs from more close-packed facets. To understand the site-specific reactivity, insight into the three-dimensional atomic arrangement of step edges is needed. Here, we employ atomic-resolution transmission electron microscopy (TEM) of nanoparticles in combination with sc

Surface redox processes involving oxygen atom exchange are fundamental in catalytic reactions mediated by metal oxides. These processes are often difficult to uncover due to changes in the surface stoichiometry and atomic arrangement. Here we employ high-resolution transmission electron microscopy to study vanadium oxide supported on titanium dioxide, which is of relevance as a catalyst in, e.g.,

The introduction of gaseous atmospheres in transmission electron microscopy offers the possibility of studying materials in situ under chemically relevant environments. The presence of a gas environment can degrade the resolution. Surprisingly, this phenomenon has been shown to depend on the electron-dose-rate. In this article, we demonstrate that both the total and areal electron-dose-rates work

Coherence estimation between speech envelope and electroencephalography (EEG) is a proven method in neural speech tracking. This paper proposes an improved coherence estimation algorithm which utilises phase sensitive multitaper cross-spectral estimation. Estimated EEG coherence differences between attended and ignored speech envelopes for a hearing impaired (HI) population are evaluated and compa

This work establishes a computational framework for the quantification of the effect of uncertainty of material model parameters on extremal stress triaxiality and Lode angle values in plastically deformed devices, whereby stress triaxiality and Lode angle are accepted as key indicators for damage initiation in metal forming processes. Attention is paid to components, the material response of whic

Purpose The study aims to develop easy-to-implement concomitant field-compensated gradient waveforms with varying velocity-weighting (M1) and acceleration-weighting (M2) levels and to evaluate their efficacy in correcting signal dropouts and preserving the black-blood state in liver diffusion-weighted imaging. Additionally, we seek to determine an optimal degree of compensation that minimizes sign

High-resolution time-frequency (TF) images of multi-component signals are of great interest for visualization, feature extraction and estimation. The matched Gaussian multitaper spectrogram has been proposed to optimally resolve multi-component transient functions of Gaussian shape. Hermite functions are used as multitapers and the weights of the different spectrogram functions are optimized. For

Immune thrombocytopenia (ITP) is characterized by a dysregulated immune response against platelets, affecting both their destruction and production. A role for an abnormal T-cell compartment has been established in ITP pathogenesis and treatments that increase platelet counts in patients with ITP have shown improvements in T-cell profiles. On the other hand, patients who were refractory to treatme

Rationale & Objective: Use of cystatin C in addition to creatinine to estimate glomerular filtration rate (estimated glomerular filtration rate based on cystatin C [eGFRcys] and estimated glomerular filtration rate based on creatinine [eGFRcr], respectively) is increasing. When eGFRcr and eGFRcys are discordant, it is not known which is more accurate, leading to uncertainty in clinical decisio

This article is a reaction to previous appeals to widen the conceptual remit of Critical Discourse Studies (CDS). It proposes research bricolage as means for critical engagement with conceptual constructs originating from adjacent social science disciplines. Borrowing such concepts as far-right metapolitics from political science, superordinate intersectionality from gender studies, and Web 2.0 so

Evolutionen som livboj för en krympande slända Många organismer påverkas negativt av mänsklig miljöpåverkan, och riskerar att dö ut. Evolutionära processer kan dock fungera som en livboj och bromsa den negativa utvecklingen från miljöförändringar. Global uppvärmning driver en insektsart till en mindre kroppsstorlek. Men när naturlig selektion istället verkar för en stor kroppsstorlek kommer de neDue to human-induced environmental changes, many natural populations are undergoing extensive fitness declines. Natural or sexual selection could potentially shift the phenotypic mean of critical traits towards new phenotypic optima, promoting evolutionary rescue. However, this process has rarely been studied in natural populations. Furthermore, the population fitness can also be increased by gene

Spinosad: en pollinatörs mardröm Bekämpningsmedel är vanliga i jordbruket för att säkra skördar, men kan ha negativa effekter på nyttiga insekter. Spinosad, ett biologiskt bekämpningsmedel framställt ur bakterier och godkänt inom ekologiskt jordbruk i EU, angriper insekters nervsystem och orsakar muskelsammandragningar, förlamning och död. Mitt experiment visar att spinosad i fältrealistiska koncThe extensive use of pesticides within the agricultural landscape is essential for maintaining sufficient yields and sustaining our growing population, however, their widespread use is not without costs. Increasing evidence shows that pesticides harm many non-target organisms, including those providing vital ecosystem services. Pollinators, for instance, are critical for the fruiting of nearly 75%

Background: A Swedish version of the Patient-Rated Ulnar Nerve Evaluation (PRUNE-S), a patient-reported outcome measure for ulnar nerve entrapment, was created, according to cross-cultural adaptation guidelines, and reliability, validity, and responsiveness were evaluated. Methods: In total, 43 patients (mean [SD] age, 49 [16] y; 54% men) were consecutively examined, including the PRUNE-S (retest:

The development of EU labour and social law has been described as a pendulum in the sense of focus shifting between economic interests, such as competitiveness for industry, and social interests, such as improving working and living conditions. This view is to a large extent based on the presumption that those interests are contrasting and pursuing one of them would necessarily exclude the promoti