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Focal EEG findings in juvenile absence syndrome and the effect of antiepileptic drugs

The presence of focal EEG abnormalities in juvenile absence syndrome (JAS) may cause it to be misdiagnosed as focal epilepsy. The purpose of our study was to determine the presence of focal EEG abnormalities in patients with JAS and to ascertain whether some clinical features or antiepileptic drugs (AEDs) have an effect on focality. Serial EEGs of 52 consecutive patients with JAS were retrospectiv

Effect of polymorphism on in vitro-in vivo properties of carbamazepine conventional tablets

The objective of the present study was to investigate the effect of polymorphism on in vitro-in vivo properties of carbamazepine (CBZ). For this purpose, three different polymorphs and a dihydrate of CBZ were obtained and the conventional tablets of these crystalline forms at the dose of 200 mg were prepared. The polymorphs were examined by the IR and DSC analysis. The tablets were investigated by

Converging applications for active ageing policy

Purpose - This article attempts to match the future needs of older people with the possibilities arising from applications based on new technology. Design/methodology/approach - This article examines the implications of novel applications for active ageing policy. These applications are forecast to arise from the convergence of two or more previously separated science disciplines and technologies,

Dimension spectra for multifractal measures with connections to nonparametric density estimation

We consider relations between Rényi's and Hentschel - Procaccia's definitions of generalized dimensions of a probability measure μ, and give conditions under which the two concepts are equivalent/different. Estimators of the dimension spectrum are developed, and strong consistency is established. Particular cases of our estimators are methods based on the sample correlation integral and box counti

Is the fatty raised lesion a pre-atheromatous lesion? - A preliminary study

Traditionally, atherosclerosis has been evaluated macroscopically from the presence of fatty streaks (FS), fibrous plaques (FBP), and complicated lesions (CL). In this preliminary study, employing aortas from autopsied middle-aged or older persons we investigated the fatty raised lesion (FRL) to elucidate its significance and histological features. The FRL is determined macroscopically from its di

Decline in FEV1 and hospitalized exacerbations in individuals with severe alpha-1 antitrypsin deficiency

Background and aim: The value of the forced expiratory volume in one second (FEV1) is useful in the diagnosis and prognosis of chronic obstructive pulmonary disease (COPD). Previous studies on lung function in individuals with severe alpha-1 antitrypsin deficiency (AATD) have shown a variable annual decline in FEV1 (∆FEV1). The aim of this study was to analyze ∆FEV1 and to identify risk factors fo

Nonlinear waveguides

We investigate the propagation of electromagnetic waves in a cylindrical waveguide with an arbitrary cross section filled with a nonlinear material. The electromagnetic field is expanded in the usual eigenmodes of the waveguide, and the coupling between the modes is quantified. We derive the wave equations governing each mode with special emphasis on the situation with a dominant TE mode. The resu

Frequency of penicillin-resistant pneumococci in children is correlated to community utilization of antibiotics

Objective. To study the impact of the utilization of antibiotics in children at the population level on the frequency of penicillin-nonsusceptible pneumococci (PNSP). Design. Children ages 0 to 6 years with a nasopharyngeal culture of PNSP were registered on place of residency in the 20 municipalities of the former Malmohus County (since 1998 a part of Skane County). Where possible the total numbe

Congenital absence of the intrahepatic portion of the portal vein in an adult male resected for hepatocellular carcinoma

We report a case of congenital absence of the portal vein (CAPV) in an adult male who underwent resection for hepatocellular carcinoma. CAPV is a rare anomaly; only 29 cases, mostly in children, have been presented to date. An association between CAPV and cardiac abnormalities, polysplenia syndrome, skeletal abnormalities and liver tumors has been seen in children. To the best of our knowledge thi

Immunohistochemical expression of metallothionein in resected hepatic primary tumors and colorectal carcinoma metastases

Metallothionein is a protein with affinity for metals and is present in several tumors. We examined its immunohistochemical expression in 37 resected primary liver tumors and 117 colorectal metastases. The reaction was intense in the two fibrolamellar hepatocellular carcinomas and in many of the hepatocytes of the pseudotumor case of focal nodular hyperplasia. The reaction was low or moderate in 5

Liver resections for metastases from intraabdominal leiomyosarcoma

This paper discusses liver resection for intraabdominal leiomyosarcoma metastases as a therapy for carefully selected patients. Of the 83 hepatectomies performed from 1992 to 1996, five were resections for liver metastases due to intraabdominal leiomyosarcoma, in 3 patients. The surgical indication was single liver metastases, without any evidence of extrahepatic disease. No mortality occurred dur

Dearterialization of colorectal liver cancer : Institutional experience

Background/Aims: Preliminary clinical trials have suggested that dearterialization (interruption of arterial blood supply) is beneficial to patients with liver tumours. The aim of this report was to review the outcome of all patients undergoing dearterialization for colorectal liver metastases and to analyze whether refinement of the technique was followed by improvement in outcome. Methods: Retro