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VEGF-C-mediated cardiac lymphangiogenesis promotes inflammation resolution in autoimmune acute myocarditis in mice

Aims: Acute myocarditis is an immune-mediated inflammatory disease characterized by myocardial inflammation and oedema. Although cardiac lymphatic vessels are essential for fluid clearance and immune regulation, their role in modulating autoimmune cardiac inflammation remains largely undefined. We aimed to determine whether promoting lymphangiogenesis could mitigate inflammation and preserve cardi

In-situ synchrotron X-ray diffraction study of microstructure and strain evolution in brazed stainless steel joints under tensile loading

Brazed stainless steel joints are critical in heat exchanger applications but often suffer from residual stresses and brittle intermetallics. Using in-situ synchrotron X-ray diffraction and fluorescence at the DanMAX beamline, we investigated Fe-based filler joints in SS316 under tensile loading. Elemental mapping and phase analysis revealed distinct interfacial solidification zones (ISZ), atherma

Ring modepolisen! Grammatiska och moraliska modebrott: En studie av modets språkliga och sociala aspekter

I den här uppsatsen argumenterar jag för att mode är ett symbolsystem som är mer likt språket än vad konsten är likt språket. Med andra ord så menar jag att mode överlag befinner sig närmare konsten än vad det gör språket, men på skalan mellan språk och konst så befinner sig mode snäppet närmare språket. Med utgångspunkt i Nelson Goodmans teorier om symbolsystem, Ingrids Loscheks applikation av Ni

If One Thinks About Raping Someone in the Woods and No One Knows, is it Wrong? An Argument for the Moral Relevance of Thoughts*

There are arguments around the nature and boundaries of the moral domain, with this current paper aiming to delineate one of these arguments. With a basis in George Sher's (2021) discussion of cognitions (beliefs, fantasies, attitudes and some thoughts), the paper defends the notion that they are, in fact, morally relevant. By combining the logic of truth-aptness with the phenomenology of agen

Steget före: hyresgästrisk i det svenska kontorssegmentet

Städer världen över har sedan pandemin genomgått en, för många, dold förändring. De av gemene man ofta förbisedda kontorslokalerna, som historiskt mer eller mindre hyrt ut sig själva, ekar numera på flera håll tomma. David Lindskog och Elmer Olsson har, i ett examensarbete vid LTH, studerat drivkrafterna bakom vakansutvecklingen i kontorssegmentet och hur riskinformation om kontorshyresgäster kan The Swedish office real estate market has entered a period marked by rising vacancies, accelerating polarization between submarkets, and a structural reorientation of tenant demand partly as a result of hybrid work trends. Earlier research has established that tenant characteristics, creditworthiness, sector exposure, contract structure, and concentration bear directly on risk, property values, an

Assessing the Organizational Value and Cost of Emerging Data-as-a-Service

In recent decades, organizations have undergone a fundamental shift from selling physical products to offering services and most recently, data-driven offerings. This transition has elevated data to a central organizational resource and given rise to new service models, most notably Data-as-a-Service, DaaS. While the costs associated with developing and maintaining data infrastructure are often me

Introduktion av precisionsdiagnostik i svensk hälso- och sjukvård: En hälsoekonomisk och organisatorisk konsekvensanalys av helgenomsekvensering vid barncancer

Denna artikel bygger på ett examensarbete genomfört vid Karolinska Universitetssjukhuset och sammanfattar dess genomförande och mest centrala insikter. Genom en scenariobaserad fallstudie analyserades de hälsoekonomiska och de organisatoriska konsekvenserna av att införa helgenom- och heltranskriptomsekvensering inom den kliniska rutinen för barncancer, i jämförelse med konventionella diagnostik mPrecision medicine is transforming healthcare by enabling diagnostics and treatment tailored to each patient’s unique biological characteristics. Whole genome sequencing and whole transcriptome sequencing (WGTS) have recently been introduced as clinical routine for pediatric cancer in Sweden, but the health economic and organizational consequences of this shift have not yet been fully mapped. Th

Everything's Bigger in Texas, even the Opportunities

Texas is the leading destination for foreign direct investment in the United States. The opening of a Swedish Consulate General in the state in 2026 underscores its growing importance for Swedish corporate expansion. Swedish presence in the state, however, is concentrated in Dallas-Fort Worth and Houston and remains thin in Austin and at the start-up and scale-up level. The Texan business landscap

International Market Expansion Strategy for High-Tech B2B Platform Companies

Sweden has established itself as one of the world’s most dynamic environments for digital innovation, producing globally successful B2C platform companies despite its small domestic market. Building on strong social infrastructure, high digital maturity, and adaptive legal and economic systems, the country has fostered firms such as Spotify, Klarna, Skype, and Mojang Studios, demonstrating how Swe

Investigating Production Planning and Scheduling Approaches in Sawmill Operations

This thesis addresses production planning and scheduling in sawmill operations, which involve a unique production flow characterized by both divergence and convergence. The study is conducted in collaboration with Södra Skogsägarna ekonomisk förening. Its objective is to identify existing production planning and scheduling approaches from the academic literature and to select the most suitable app

Maximizing Value-To-Effort Using Digital Twins in a Rapidly Moving Spare Parts Supply Network

Abstract Title: Maximizing Value-to-Effort using Digital Twins in a Rapidly Moving Supply Network Authors: André Laurent – Hedlund & Oskar Helén Cedergren Supervisors: Sandeep Jagtap, Senior Lecturer at Engineering Logistics, Faculty of Engineering (LTH) at Lund University Digitalization Manager at The Company Examiner: Andreas Norrman, Professor at Engineering Logistics, Faculty of Enginee

The association between outdoor temperature during the past weeks and current fluid homeostasis

BACKGROUND: It remains unclear why cool temperatures cause more persistent adverse health effects compared to hot weather. Fluid homeostasis may constitute a causal link between past temperatures and adverse health effects. In this study we investigated the association between past outdoor temperatures and current fluid homeostasis.METHODS: We studied participants from five cohorts during three de

Preoperative myocardial strain, mesenteric resistance, and aortopulmonary collateral flow are associated with pleural effusion duration after fontan completion

Introduction: The contribution of aortopulmonary collateral (APC) flow to pleural effusion (PE) after total cavopulmonary connection (TCPC) remains unclear. Excessive APC flow may alter mesenteric perfusion and increase ventricular volume load. We evaluated echocardiographic and mesenteric flow parameters as predictors of PE duration and their association with magnetic resonance imaging (MRI)-deri

Mechanistic insight into graphene coatings for oral biofilm inhibition and osteoblast compatibility

The initial adhesion of bacterial cells to implant surfaces is a critical step in the development of biofilms, complex microbial communities that are highly resistant to conventional antimicrobial treatments. Once established, these biofilms and their self-produced extracellular matrix are difficult to eradicate. As a result, there is growing interest in engineering implant surfaces that can effec

Nocturnal melatonin secretion and risk of type 2 diabetes : a prospective cohort study

CONTEXT: Melatonin regulates circadian rhythms and influences glucose metabolism. Altered melatonin secretion may contribute to the pathogenesis of type 2 diabetes (T2D), but prospective population-based evidence is scarce.OBJECTIVE: To examine whether low nocturnal melatonin secretion is associated with an increased risk of incident T2D in adults.METHODS: This prospective cohort study, with follo

Factors affecting nurses' acceptance of a digital triage platform in primary health care in Sweden : an extended UTAUT analysis

BACKGROUND: Digital symptom checkers might help facilitate effective triage in primary healthcare. However, evidence regarding their acceptance among healthcare professionals remains limited. Identifying key factors of adoption is essential for successful integration into clinical practice.This study aims to identify factors most relevant to nurses' acceptance of a newly implemented digital triage

Feasibility testing of a home-based exercise intervention in children with cerebral palsy who are ambulant-a study protocol of the HOME-EX study

UNLABELLED: Children gain increased health and well-being by participating in physical activity. Children with cerebral palsy who are ambulatory (CP-A) are known to be less physically active than children without physical disabilities, making them an important group of children to support in becoming more physically active. Assistive technologies, such as eHealth, may support physical exercise in

Distinct uniaxial stress and pressure fingerprint of superconductivity in the 3D kagome lattice compound CeRu2

The exploration of tunable superconductivity in strongly correlated electron systems is a central pursuit in condensed matter physics, with implications for both fundamental understanding and potential applications. The Laves phase CeRu2, a pyrochlore compound, exhibits a three-dimensional (3D) kagome lattice type geometry giving rise to flat bands and degenerate Dirac points, where band structure