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A mutation in the cell division gene ftsK causes super-induction of sigma(70)-dependent stress defense genes, such as uspA, during entry of cells into stationary phase. In contrast, we report here that stationary phase induction of sigma(S)-dependent genes, uspB and cfa, is attenuated and that sigma(S) accumulates at a lower rate in ftsK1 cells. Ectopic overexpression of rpoS restored induction of

Presently, there is no published information on the antimicrobial susceptibility pattern of H. pylori strains in Ethiopia to guide the choice of drug for therapy. Therefore, it is becoming clinically relevant to test the in vitro susceptibility of H. pylori clinical isolates prior to treating patients. Susceptibility testing was performed on 50 clinical H. pylori isolates obtained from adult dyspe

Rapporten redovisar en undersökning av energibesparing vid sänkning av temperaturen nattetid i flerbostadshus. Mätningarna visar att en 4-procentig energibesparing har uppnåtts mot en enligt beräkningar förväntad 11-procentig besparing. Utvärdering i 30 hus på fem orter och ingående i internationellt forskningssamarbete genom IEA.

Mahmoud Darwish's senaste diktsamlingar är skrivna inifrån Palestina 1997 och 2001, den sista sedan den andra intifadan brutit ut. Vi (Henry Diab & Kerstin Eksell) har förvärvat rättigheterna till dem från författaren. Översättningarna här är hämtade från vårt arbetsmaterial.

Background: The purpose was to investigate adjuvant marrow-supportive high-dose chemotherapy compared with an equitoxicity-tailored comparator arm. Patients and methods: Five hundred and twenty-five women below the age of 60 years with operated high-risk primary breast cancer were randomised to nine cycles of granulocyte colony-stimulating factor supported and individually tailored FEC (5-fluorour

The paper deals with traffic recovery in IP/MPLS network carrying traffic of different priority classes. Two off-line network design problems are presented employing two different recovery mechanisms – single backup path and failure-dependent backup path protection. Also, two routing strategies are studied in this paper. A network design problem with failure-dependent path protection mechanism com

OBJECTIVE: To examine whether adherence to the modified Mediterranean diet, in which unsaturates were substituted for monounsaturates, is associated with longer life expectancy among elderly Europeans. DESIGN: Multicentre, prospective cohort study. SETTING: Nine European countries (Denmark, France, Germany, Greece, Italy, the Netherlands, Spain, Sweden, United Kingdom). PARTICIPANTS: 74,607 men an

Popular Abstract in Swedish Stamcellsbiologi är ett vetenskapligt, kliniskt och politiskt aktuellt ämne idag. Nuförtiden används blodstamceller för att behandla patienter med blod-cancer, bröstcancer eller andra immun-försvarssjukdomar. Blodstamceller finns i benmärgen och är viktiga för blodbild-ning som pågår kontinuerligt genom hela livet hos en individ. Det finns olika slags mogna celler: rödaHematopoietic Stem Cells (HSCs) have been defined to have abilities of both self-renewal and multi-lineage differen-tiation. The balance between these abilities is rigorously controlled under steady-state status (homeostasis) and when the normal processes of self-renewal and differentiation become deregulated, a disorder of blood system (such as leukemias) can occur. HSCs are enriched in lineage n

Popular Abstract in Swedish Anglo-amerikanska relationer efter andra världskriget bestod både av samarbete och konflikt. Ett exempel på det första var Pentagondiskussionerna 1947 då ett amerikanskt uttalande betonade det generella målet att upprätthålla säkerheten i Mellanöstern genom att stödja de brittiska politiska, ekonomiska och strategiska positionerna i området. Ett exempel på det senare vaAnglo-American post-Second World War relations in the Middle East included cases of close cooperation and conflict. An example of the former was the Pentagon Talks in 1947 when an American statement pointed out the general objective of maintaining the security of the Middle East by retaining the British political, economic, and strategic position in areas supported by the United States. An example

För den som vill ha något att bita finns det många angelägna projekt inom lavsystematiken. Ett släkte som inte har rönt någon större uppmärksamhet de senaste 50 åren är Candelariella, ägglavarna, med sin svårbegripliga arttaxonomi. Nu finns en avhandling som förhoppningsvis kan kasta lite ljus på systematiken inom detta släkte. Martin Westberg, en av våra redaktörer, är författare till denna och s

Background: Despite the lack of randomized trials supporting the laparoscopic approach, laparoscopic antireflux surgery has gained widespread acceptance during the last decade. The aim of this study was to compare the short-term symptomatic and objective outcome after laparoscopic and open 360 degrees fundoplication in a prospective randomized clinical trial. Methods: Sixty patients with GERD were

Sudden, spontaneous, unilateral loss of vestibular function without simultaneous hearing loss or brain stem signs is generally attributed to a viral infection involving the vestibular nerve and is called acute vestibular neuritis. The clinical hallmarks of acute vestibular neuritis are vertigo, spontaneous nystagmus, and unilateral loss of lateral semicircular function as shown by impulsive and ca

BACKGROUND: High-resolution microarray-based comparative genomic hybridization (CGH) techniques have successfully been applied to study copy number imbalances in a number of settings such as the analysis of cancer genomes. For normalization of array-CGH data, methods initially developed for gene expression microarray analysis have, in general, been directly adopted and used. However, these methods

Genom ett antal artskilda exempel - valda fran det byggnadstekniska området i vid mening - har vi nu försökt belysa några karakteristiska fenomen inom teknikhistorien. Från den inledande beskrivningen av geodesins utveckling har vi kunnat observera den växling, som skett historiskt av denna vetenskaps referensram. I den tidiga historien gav därvid studier av fenomen på jorden underlaget för uppfat

BACKGROUND: Vascular endothelial growth factors (VEGFs) and their receptors are essential regulators of vasculogenesis and angiogenesis in both embryos and adults. One of the factors with a still unknown physiological function is VEGF-B, which is expressed in many tissues, including the heart. METHODS AND RESULTS: Mice carrying a targeted deletion in the VEGF-B gene were developed. In VEGF-B(-/-)

Accurate chronologies are essential for linking palaeoclimate archives. Carbon-14 wiggle-match dating was used to produce an accurate chronology for part of an early Holocene peat sequence from the Borchert (The Netherlands). Following the Younger Dryas-Preboreal transition, two climatic shifts could be inferred. Around 11 400 cal. yr BP the expansion of birch (Betula) forest was interrupted by a