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Context: Autoimmune hypothyroidism is a common endocrine disorder affecting 1% to 2% of the population in iodine sufficient areas. While levothyroxine is standard treatment, a substantial number of patients report persistent symptoms despite adequate treatment. The use of liothyronine as an adjunct to levothyroxine therapy has increased. The psychiatric characteristics of patients receiving liothy

Cardiovascular-kidney-metabolic (CKM) syndrome affects approximately 90% of US adults, arising from the convergence of metabolic dysfunction, chronic kidney disease (CKD), and cardiovascular disease (CVD). These conditions create self-reinforcing cycles of multiorgan damage, substantially increasing mortality risk. The American Heart Association’s 2023 staging framework stratifies CKM from stage 0

The discrete Fourier transform (DFT) is one of the most important algorithms commonly used in baseband processing. While traditional hardware implemen- tations like the Fast Fourier Transform (FFT) are highly optimized, they heav- ily suffer from the von Neumann bottleneck. To overcome this, performing the computations directly in memory using memristive crossbar arrays is a promising solution. Th

Träets inneboende motståndskraft mot svampnedbrytning studerades med hjälp av paste test metoden. Prover av tre olika träslag, rödgran (Picea abies), tall (Pinus sylvestris) och bok (Fagus sylvatica), maldes först till pulver och inokulerades sedan med två typer av rötsvampar, brunrötsvamp (Rhodonia placenta) och vitrötsvamp (Trametes versicolor). För att analysera hur olika modifieringsmetoder kaThe inherent resistance to fungal degradation of wood was studied using the paste test method. Samples of three different types of wood, Norway spruce (Picea abies), Scots pine (Pinus sylvestris) and European beech (Fagus sylvatica), were initially ground to a powder followed by being inoculated with two types of rot fungi, brown rot fungus (Rhodonia placenta) and white rot fungus (Trametes versic

Formkollapser är ett av de mest kritiska problemen inom stålgjutning med V-processen. Varje gång en gjutform ger vika innebär det en kassation av detaljen, vilket medför stora ekonomiska förluster. I detta examensarbete, utfört i samarbete med en partner i industrin, har vi undersökt sandens dolda egenskaper för att förstå varför stabiliteten i processen varierar och hur man kan stoppa slöseriet. This study, conducted in collaboration with a industrial steel foundry, investigates how variations in sand properties influence mold stability in the V‑process, a vacuum‑assisted molding technique used in steel casting. A mixed‑method approach was applied, combining analysis of historical data, laboratory permeability testing, personnel interviews, and data-driven permeability modeling to identif

BACKGROUND: Alzheimer's disease pathology can be accurately identified with blood biomarkers (core 1 biomarkers), including plasma p-tau217 tests. Biomarkers that change longitudinally after diagnosis (core 2 biomarkers) can increase confidence that Alzheimer's disease pathology is contributing to cognitive symptoms. Plasma eMTBR-tau243 reflects tau tangle pathology and is a promising core 2 bioma

Out-of-pocket (OOP) expenditures for childbirth in Bangladesh have increased substantially, intensifying financial pressure on lower-income households. While wealthier groups historically bore higher delivery costs, recent trends indicate a narrowing gap in spending across socioeconomic strata. This study investigates the drivers of this convergence in delivery-related expenditures between 2014 an

BackgroundWomen’s empowerment may influence non-communicable disease (NCD) risk. However, evidence on these associations among women in Bangladesh remains limited. This study examined the associations between women’s empowerment and the prevalence of selected non-communicable conditions among ever-married reproductive-aged women in Bangladesh.MethodsData from the 2022 Bangladesh Demographic and He

Motivation Machine learning offers a powerful approach for building predictive models from high-dimensional molecular data. Omics technologies such as transcriptomics, proteomics, and metabolomics quantify thousands of molecules simultaneously, providing deep insights into disease biology. Integrating multiple modalities can enhance predictive performance, as shown in histology-omics and holter-om

Introduction: Using time-limited trials of low-dose, sustained-release morphine to reduce chronic breathlessness to evaluate net effects may generate opioid withdrawal symptoms if medication is ceased. This sub-study of a larger randomized, placebo-controlled, double-blind trial aimed to evaluate if this occurred. Methods: People with modified Medical Research Council breathlessness scores of 3 or

Antipsychotics are mainly used for severe psychiatric disorders. Risperidone is the only antipsychotic approved for younger children. Aripiprazole is approved for older children, ziprasidone and lurasidone for adolescents. To describe paediatric utilisation of antipsychotic drugs in Sweden. Dispensations of antipsychotic drugs to children aged 5–17 years from 2008 to 2021 were analysed using the N

Taylor Swift is one of today’s most beloved songwriters, however, all aspects of her work are not recognised. Swift frequently references queerness, yet this is often overlooked. Previous scholarship focused on Swift and queerness has either centred around Swift’s support for LGBTQ+ causes or the subgroup of Swift’s fans who acknowledges and embraces her expressed queerness, but textual analysis o

Att bygga en proteinmodell, strukturbestämning av ett förmodat urokanatreduktas Kardiometabola sjukdomar som hjärtsvikt och typ 2 diabetes blir allt vanligare. Studier har lyckats hitta en länk mellan den mänskliga bakteriefloran och utvecklingen av sådana sjukdomar. En metabolit, imidazolpropionat (ImP), produceras av bakterier och kan tas upp samt transporteras via blodet. Väl i blodet kan den