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The Gaia -ESO Survey : Spectroscopic-asteroseismic analysis of K2 stars in Gaia -ESO

Context. The extensive stellar spectroscopic datasets that are available for studies in Galactic Archeaology thanks to, for example, the Gaia-ESO Survey, now benefit from having a significant number of targets that overlap with asteroseismology projects such as Kepler, K2, and CoRoT. Combining the measurements from spectroscopy and asteroseismology allows us to attain greater accuracy with regard

Increased Plasma Soluble Interleukin-2 Receptor Alpha Levels in Patients With Long-Term Type 1 Diabetes With Vascular Complications Associated With IL2RA and PTPN2 Gene Polymorphisms

Type 1 diabetes (T1D) is largely considered an autoimmune disease leading to the destruction of insulin-producing pancreatic β cells. Further, patients with T1D have 3–4-fold increased risk of developing micro- and macrovascular complications. However, the contribution of immune-related factors contributing to these diabetes complications are poorly understood. Individuals with long-term T1D who d

COVID-19 during Pregnancy and Postpartum:: I) Pathobiology of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) at Maternal-Fetal Interface

Coronavirus Disease 2019 (COVID-19) triggered by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection has been declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Oxidative stress and its related metabolic syndromes are potential risk factors in the susceptibility to, and severity of COVID-19. In concert with the earliest reports of COVID-19, obstetricia

Pronounced Plastic and Evolutionary Responses to Unpredictable Thermal Fluctuations in Drosophila simulans

Organisms are exposed to temperatures that vary, for example on diurnal and seasonal time scales. Thus, the ability to behaviorally and/or physiologically respond to variation in temperatures is a fundamental requirement for long-term persistence. Studies on thermal biology in ectotherms are typically performed under constant laboratory conditions, which differ markedly from the variation in tempe

Gender differences in self-care for common colds by primary care patients : a European multicenter survey on the prevalence and patterns of practices (the COCO study)

Although generally harmless, the common cold disturbs the lives of billions yearly. It is frequently treated by self-care, yet little is known about the effect gender may have on self-care. Our study set out to discover whether self-care for common colds differs by gender. We also wanted to test the ‘Man cold’ belief: that men ‘break down’ when they have a cold and suffer more than women when they

Risk of digestive cancers in a cohort of 69 460 five-year survivors of childhood cancer in Europe: The PanCareSurFup study

Background: Survivors of childhood cancer are at risk of subsequent primary neoplasms (SPNs), but the risk of developing specific digestive SPNs beyond age 40 years remains uncertain. We investigated risks of specific digestive SPNs within the largest available cohort worldwide. Methods: The PanCareSurFup cohort includes 69 460 five-year survivors of childhood cancer from 12 countries in Europe. R

Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality: EPIC cohort study in 10 European countries

Objective To determine if the Food Standards Agency nutrient profiling system (FSAm-NPS), which grades the nutritional quality of food products and is used to derive the Nutri-Score front-of-packet label to guide consumers towards healthier food choices, is associated with mortality. Design Population based cohort study. Setting European Prospective Investigation into Cancer and Nutrition (EPIC) c

Poly(alkanoyl isosorbide methacrylate)s: from amorphous to semi-crystalline and liquid crystalline biobased materials

We have prepared a series of twelve D-isosorbide-2-alkanoate-5-methacrylate monomers as single regioisomers with different pendant linear C2 to C20 alkanoyl chains by using biocatalytic and chemical acylations. By conventional radical polymerization, these monomers afforded high-molecular weight biobased poly(alkanoyl isosorbide methacrylate)s (PAIMAs). Samples with C2-C12 alkanoyl chains were amo

J/ψ production as a function of charged-particle multiplicity in p-Pb collisions at √sNN = 8.16 TeV

Inclusive J/ψ yields and average transverse momenta in p-Pb collisions at a center-of-mass energy per nucleon pair sNN = 8.16 TeV are measured as a function of the charged-particle pseudorapidity density with ALICE. The J/ψ mesons are reconstructed at forward (2.03 < ycms< 3.53) and backward (−4.46 < ycms< −2.96) center-of-mass rapidity in their dimuon decay channel while the charged-particle pseu

Rocking-Chair Proton Batteries with Conducting Redox Polymer Active Materials and Protic Ionic Liquid Electrolytes

Rechargeable batteries that use redox-active organic compounds are currently considered as an energy storage technology for the future. Functionalizing redox-active groups onto conducting polymers, to make conducting redox polymers (CRPs) can effectively solve the low conductivity and dissolution problems of redox-active compounds. Here we employ a solution-processible postdeposition polymerizatio

Quality of life of patients with osteosarcoma in the european american osteosarcoma study-1 (EURAMOS-1) : Development and implementation of a questionnaire substudy

Background: The quality of life (QoL) of patients with osteosarcoma (OS) may be adversely affected by the disease or its treatment. Therefore, it is important to understand the QoL of patients undergoing treatment for OS to improve the QoL. We report on the first prospective international QoL study that was embedded within a large randomized clinical trial from 4 national study groups. Objective:

Nordic Security and Defence Cooperation: Differentiated Integration in Uncertain Times

A decade ago, Nordic cooperation on security and defence matters gained momentum, having been largely absent fromthe map of Nordic cooperation during the Cold War and its aftermath. This article analyses developments along three dimensionsof Nordic cooperation: military defence (focusing on the Nordic Defence Cooperation), civil security (in the formof the ‘Haga’ process), and political cooperatioA decade ago, Nordic cooperation on security and defence matters gained momentum, having been largely absent fromthe map of Nordic cooperation during the Cold War and its aftermath. This article analyses developments along three dimensionsof Nordic cooperation: military defence (focusing on the Nordic Defence Cooperation), civil security (in the formof the ‘Haga’ process), and political cooperatio

A nationwide study on inpatient opportunistic infections in patients with chronic lymphocytic leukemia in the pre-ibrutinib era

Objective: Opportunistic infections in chronic lymphocytic leukemia (CLL) have been described in clinical trials, single-center studies, and case reports. We performed a nationwide study to estimate the incidence and impact of inpatient opportunistic infections. Methods: The incidence rate (IR) and incidence rate ratio (IRR) for Swedish CLL patients diagnosed 1994-2013, and matched controls were c

Reference study of CityGML software support : The GeoBIM benchmark 2019—Part II

OGC CityGML is an open standard for 3D city models intended to foster interoperability and support various applications. However, through our practical experience and discussions with practitioners, we have noticed several problems related to the implementation of the standard and the use of standardized data. Nevertheless, a systematic investigation of these issues has never been carried out, and

Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression

Stromal stiffening accompanies malignancy, compromises treatment and promotes tumour aggression. Clarifying the molecular nature and the factors that regulate stromal stiffening in tumours should identify biomarkers to stratify patients for therapy and interventions to improve outcome. We profiled lysyl hydroxylase-mediated and lysyl oxidase-mediated collagen crosslinks and quantified the greatest

Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial

Background: Intravenous ferric carboxymaltose has been shown to improve symptoms and quality of life in patients with chronic heart failure and iron deficiency. We aimed to evaluate the effect of ferric carboxymaltose, compared with placebo, on outcomes in patients who were stabilised after an episode of acute heart failure. Methods: AFFIRM-AHF was a multicentre, double-blind, randomised trial don

Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes : An IMI-DIRECT study

AIM: Subclasses of different glycaemic disturbances could explain the variation in characteristics of individuals with type 2 diabetes (T2D). We aimed to examine the association between subgroups based on their glucose curves during a five-point mixed-meal tolerance test (MMT) and metabolic traits at baseline and glycaemic deterioration in individuals with T2D. METHODS: The study included 787 indi

Connecting the data landscape of long-term ecological studies: The SPI-Birds data hub

The integration and synthesis of the data in different areas of science is drastically slowed and hindered by a lack of standards and networking programmes. Long-term studies of individually marked animals are not an exception. These studies are especially important as instrumental for understanding evolutionary and ecological processes in the wild. Furthermore, their number and global distributio