A PtdIns 4-kinase was purified extensively from rat liver exocytotic vesicles. The enzyme had a low Km for ATP, was inhibited by adenosine, and had an apparent molecular mass of 54 kDa, indicating it to be a type II PtdIns-kinase. The activity of the purified enzyme was enhanced several-fold by PtdCho, and to some extent by other phospholipids with basic polar head groups, and was inhibited by Ptd

LCG and ARC are two of the major production-ready Grid middleware solutions being used by hundreds of HEP researchers every day. Even though the middlewares are based on same technology, there are substantial architectural and implementational divergencies. An ordinary user faces difficulties trying to cross the boundaries of the two systems: ARC clients so far have not been capable accessing LCG

The base (BOP) and the top (TOP) of the world income pyramid represent the poor people and the people from developed countries, respectively. About two-fifths of the world population can be categorized as poor. Poverty is a trap because children born to poor parents are likely to grow up to be poor adults. In recent years, a poverty reduction approach that combines business development with povert

Many computing systems are constrained by power budgets. While they could temporarily draw more power, doing so creates unsustainable temperatures and unwanted electricity consumption. Developing systems that operate within power budgets is a constrained optimization problem: configuring the components within the system to maximize performance while maintaining sustainable power consumption. This

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Popular Abstract in Swedish Den här avhandlingens syfte var att undersöka hur väl barn kan återberätta en bevittnad händelse och vid behov identifiera en misstänkt gärningsman i en ”lineup”, en vittneskonfrontation där en misstänkt tillsammans med fem personer som liknar den misstänkte presenteras på fotografier. Tre studier genomfördes. Den första studien undersökte barns förmåga att återberätta Through centuries, witnesses to crimes have played an important role for the police to get a conviction of the culprit. This dissertation examined how accurate children are as witnesses of events and when participating in lineups. In Study 1, participants were tested with free recall and focussed questions. Children aged 8-9 years, 11-12 years and adults in two experiments witnessed film events

Understanding the molecular details of bioenergetic processes is fundamentally important. Defects in the mitochondrial energy metabolism can lead to untimely apoptosis and thus cause serious degenerative human diseases. Other defects in mitochondrial energy metabolism can have the reverse effect and cause cell immortality and also contribute to and high metastatic potential of tumor cells. Knowi

The purpose of the presented garbage collector interface is to provide a universal interface for many different implementations of garbage collectors. This is to simplify the integration and exchange of garbage collectors, but also to support incremental, non-conservative, and thread safe implementations. Due to the complexity of the interface, it is aimed at code generators and preprocessors. Exp

The astrometric satellite Gaia was launched in December, 2013. It will observe nearly one billion stars in the Milky Way and beyond along with many extragalactic objects such as quasars and galaxies. The analysis of quasar data will provide the optical counterpart of the International Celestial Reference Frame (ICRF). Also, the analysis of data for stars in our Galaxy provide a revolution in our u