No title
The role of the intermediate filament protein desmin in hypertrophy of smooth muscle was examined in desmin deficient mice (Des -/-). A partial obstruction of the urethra was created and after 9-19 days bladder weight increased about 3-fold in both Des -/- and wild type (Des +/+) animals. Bladder growth was associated with synthesis of actin and myosin. In the hypertrophic Des +/+ bladder the rela
