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Active faulting and seismic hazard in the Outer Western Carpathians (Polish Galicia) : Evidence from fractured Quaternary gravels

This report opens a new window on Quaternary tectonics of the Outer Western Carpathians. We discuss results of fractured clasts analysis in Quaternary fluvial gravels within a 4.500 km2 large area comprising a part of the Outer Carpathians including Nowy Sącz Intramontane Basin (NSIB) as well as in the innermost part of the Carpathian Foredeep. Quaternary gravels bearing fractured clasts are wides

Molecular tests support the viability of rare earth elements as proxies for fossil biomolecule preservation

The rare earth element (REE) composition of a fossil bone reflects its chemical alteration during diagenesis. Consequently, fossils presenting low REE concentrations and/or REE profiles indicative of simple diffusion, signifying minimal alteration, have been proposed as ideal candidates for paleomolecular investigation. We directly tested this prediction by conducting multiple biomolecular assays

Stepwise modeling and the importance of internal variables validation to test model realism in a data scarce glacier basin

Model realism is of vital importance in science of hydrology, in terms of realistic representation of hydrological processes and reliability of future prediction. Here, we employed a stepwise modeling approach that leverages flexible model structures and multi-source observations for robust streamflow simulation and internal variables validation with improved model realism. This framework is demon

Decrease in amygdala activity during repeated exposure to spider images predicts avoidance behavior in spider fearful individuals

Spider phobia is characterized by exaggerated fear of situations where spiders could be present, resulting in avoidance of such situations and compromised quality of life. An important component in psychological treatment of spider phobia is exposure to phobic situations that reduces avoidance behaviors. At the neural level, amygdala responses to phobic material are elevated, but normalizes follow

Predictive Factors for Postoperative Pancreatic Fistula—A Swedish Nationwide Register-Based Study

Background: A serious complication after pancreatoduodenectomy (PD) is postoperative pancreatic fistula (POPF). The aim of this study was to analyse the incidence and predictive factors for POPF by using a large nationwide cohort. Methods: Data from the Swedish National Registry for Pancreatic and Periampullary Cancer for all patients undergoing a PD from 2010 until 30th June 2018 were collected.

Femtosecond laser produced periodic plasma in a colloidal crystal probed by XFEL radiation

With the rapid development of short-pulse intense laser sources, studies of matter under extreme irradiation conditions enter further unexplored regimes. In addition, an application of X-ray Free-Electron Lasers (XFELs) delivering intense femtosecond X-ray pulses, allows to investigate sample evolution in IR pump - X-ray probe experiments with an unprecedented time resolution. Here we present a de

Compressive Sensing for Dynamic XRF Scanning

X-Ray Fluorescence (XRF) scanning is a widespread technique of high importance and impact since it provides chemical composition maps crucial for several scientific investigations. There are continuous requirements for larger, faster and highly resolved acquisitions in order to study complex structures. Among the scientific applications that benefit from it, some of them, such as wide scale brain

Cost-Driven Informed Decisions Using Loss Analyses from Production Monitoring

When embarking a cost reduction strategy, it is important to know what causes the costs, how the costs are connected to value adding and to non-value adding activities, and thereby conduct a knowledge-intensive production development. This paper present a method on how to connect costs to production losses and how they can relate to different cost factor groups. The method uses a digital tool that

Non-immune hydrops fetalis was rare in Sweden during 1997-2015, but cases were associated with complications and poor prognosis

Aim: The study was designed to document the incidence of non-immune hydrops fetalis (NIHF) at birth and characterise associated outcomes and obstetric complications. Methods: Data on more than 1.9 million births were extracted from the Swedish Birth Register for 1997-2015. Pregnancies not affected by NIHF served as controls. National registers on mortality and hospitalisations provided follow-up i

Production Logistics Visibility - Perspectives, Principles and Prospects

Globalisation, competitive markets and increasing sustainability requirements are demanding companies to focus on visibility to improve their supply chains and ultimately their businesses. This paper aims to identify perspectives, principles and prospects of production logistics visibility (PLV). The study is based on a literature review of articles presenting definitions, development trends and t

The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness

Neuroblastoma is an aggressive childhood cancer arising from sympatho-adrenergic neuronal progenitors. The low survival rates for high-risk disease point to an urgent need for novel targeted therapeutic approaches. Detailed molecular characterization of the neuroblastoma genomic landscape indicates that ALK-activating mutations are present in 10% of primary tumours. Together with other mutations c

Imaging multiphoton ionization dynamics of CH3I at a high repetition rate XUV free-electron laser

XUV multiphoton ionization of molecules is commonly used in free-electron laser experiments to study charge transfer dynamics. However, molecular dissociation and electron dynamics, such as multiple photon absorption, Auger decay, and charge transfer, often happen on competing time scales, and the contributions of individual processes can be difficult to unravel. We experimentally investigate the

Association between dietary fiber intake and risk of incident aortic stenosis

Background and aims: Although aortic stenosis is the most common valvular heart disease requiring intervention in Europe, the role that diet plays in development of the disease is largely unknown. The pathophysiology of aortic stenosis is however similar to other cardiovascular diseases that fiber intake has been associated with. The aim of this study was consequently to investigate the associatio

Socioeconomic Factors in Patients with Ulnar Nerve Compression at the Elbow : A National Registry-Based Study

Aims. To investigate demographics and socioeconomic status in patients with ulnar nerve compression and the influence of socioeconomic factors on patient-reported outcome measurements (PROM) as evaluated by QuickDASH (short version of Disabilities of Arm, Shoulder and Hand) after surgery for ulnar nerve compression at the elbow. Methods. Patients operated for primary ulnar nerve compression from 2