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Glycerol levels in adipocytes depend on the lipolysis, the hydrolysis of triglycerides into glycerol and free fatty acids, and the efflux of glycerol across the plasma membrane through glycerol channels. The aims of this work were to investigate how glycerol levels are regulated on a molecular level by PLIN1, a major lipid droplet-associated protein and a key regulator of the lipolysis by scaffold

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INTRODUCTION: In the ECG, significant ST elevation or depression according to specific amplitude criteria can be indicative of acute coronary syndrome (ACS). Guidelines state that the ST amplitude should be measured at the J point, but data to support that this is the optimal measuring point for ACS detection is lacking. We evaluated the impact of different measuring points for ST deviation on the

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A constitutive model for aluminum alloys under hot working conditions is proposed. The elastic-viscoplastic model is implemented in a finite strain continuum mechanical frame- work. The model accounts for the interplay between dynamic recovery and recrystalliza tion during hot working of aluminum alloys and central aspects of microstructure evolution such as grain/subgrain size and dislocation denA constitutive model for aluminum alloys under hot working conditions is proposed. The elastic-viscoplastic model is implemented in a finite strain continuum mechanical framework. The model accounts for the interplay between dynamic recovery and recrystallization during hot working of aluminum alloys and central aspects of microstructure evolution such as grain/subgrain size and dislocation densit

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Behavioral and electroencephalography (EEG) data were analyzed from 30 participants performing a demanding, attention-capturing task in which they had to detect an occasional decrement of luminance of small discs. Crucially, numerous white segments in the background were presented either in random orientations or configuring a contour shape of a square or a diamond. The participants' awareness of

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Dozens of morphologically differentiated populations, subspecies and species of cross- bills (genus Loxia) exist. It has been suggested that this divergence is due to variation in the conifer cones that each population specialises upon, requiring a specific beak size to efficiently separate the cone scales. If so, apparent survival should depend on beak size. To test this hypothesis, we undertook

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Building Information Modelling (BIM) objects represent building products in design, simulation, and procurement processes. This paper explores how BIM objects could be created and exchanged to enable the diffusion of innovative products with enhanced sustainability performance. Two BIM library platforms were examined by taking a new approach that integrates the concepts of sustainable value, diffu