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Synthesis and Characterization of a Biocomposite Bone Bandage for Controlled Delivery of Bone-Active Drugs in Fracture Nonunions

Fracture nonunions are common in orthopedics and their treatment often involves multiple surgical interventions. The aim of this study was to fabricate and characterize a gelatin-nano-hydroxyapatite membrane (GM)-based bone bandage for controlled delivery of bio-active molecules; recombinant human bone morphogenic protein-2 (rhBMP-2) and zoledronic acid (ZA) to promote osteoinduction and prevent c

Evaluation and optimization of ICOS atmosphere station data as part of the labeling process

The Integrated Carbon Observation System (ICOS) is a pan-European research infrastructure which provides harmonized and high-precision scientific data on the carbon cycle and the greenhouse gas budget. All stations have to undergo a rigorous assessment before being labeled, i.e., receiving approval to join the network. In this paper, we present the labeling process for the ICOS atmosphere network

Associations of carbohydrates and carbohydrate-rich foods with incidence of type 2 diabetes

Dietary carbohydrates have long been expected to be associated with risk of type 2 diabetes; however, the associations for many carbohydrates and carbohydrate-rich foods remain inconclusive. This study analysed associations between intakes of six types of carbohydrates and thirteen carbohydrate-rich foods with incident type 2 diabetes in 26 622 participants (61% women) in the Malmö Diet and Cancer

Changing the System Culture : Mobilizing the Social Sciences in the Swedish Nuclear Waste System

The purpose of this paper is to analyze how competence in the humanities and social sciences has been introduced into the system culture of the Swedish nuclear waste system (SNWS) traditionally dominated by scientists and engineers. In the spring of 1980, fierce local protests were directed against drilling teams sent out to investigate the geology of potential locations for a repository of spent

Long-term outcome of the Surgisis® (Biodesign®) anal fistula plug for complex cryptoglandular and Crohn’s fistulas

Aim: To evaluate the long-term success rate of treatment with the Surgisis® (Biodesign®) anal fistula plug for complex anal fistulas, assess fistula plug failure over time and compare success rates for fistula plug between a group of patients with cryptoglandular fistula and another group with Crohn's fistula. Method: This is a single-centre study of consecutive patients treated with the Surgisis®

Ex-situ manometric activity test for evaluation of mainstream anammox in Moving Bed Biofilm Reactors

Implementing anammox based processes in the mainstream at municipal wastewater treatment plants is challenging and requires carefully constructed control strategies in order to be successful. A method to measure the specific anammox activity was further developed and implemented in the mainstream anammox pilot plant at Sjölunda Wastewater Treatment Plant. The method was found to be reliable and re

The role of cortico-basal ganglia systems in the construction of movement: Action selection and sequencing

The cortico-basal ganglia system is instrumental in the construction of movement, through its involvement in aspects such as action selection, initiation/termination and sequencing, though the precise role of the different structures and how they collaborate on a network level to allow us to fluidly change from one behavior to another has long proven to be elusive.We have here recorded neuronal acti

Being an older family caregiver does not impact healthcare and mortality : Data from the study ‘Good Aging in Skåne’

Background: Will being a caregiver further impact the health of a group already at risk of adverse health due to old age? This study aimed to answer the questions whether short- and long-term healthcare consumption and mortality differ between informal caregivers and non-caregivers and between high-burden and low-burden informal caregivers. Method: The study population consisted of 423 caregivers

Minimal risk of contrast-induced kidney injury in a randomly selected cohort with mildly reduced GFR

Objectives: Previous large studies of contrast-induced or post-contrast acute kidney injury (CI-AKI/PC-AKI) have been observational, and mostly retrospective, often with patients undergoing non-enhanced CT as controls. This carries risk of inclusion bias that makes the true incidence of PC-AKI hard to interpret. Our aim was to determine the incidence of PC-AKI in a large, randomly selected cohort,

Exploring the stellar age distribution of the milky way bulge using APOGEE

We present stellar age distributions of the Milky Way bulge region using ages for ∼6000 high-luminosity (log(g)< 2.0), metal-rich ([Fe/H] ≥ -0.5) bulge stars observed by the Apache Point Observatory Galactic Evolution Experiment. Ages are derived using The Cannon label-transfer method, trained on a sample of nearby luminous giants with precise parallaxes for which we obtain ages using a Bayesian i

Simulation capacity building in rural Indian hospitals : A 1-year follow-up qualitative analysis

Introduction: The benefits of simulation-based medical training are well described. The most effective way to plant and scale simulation training in rural locations remains undescribed. We sought to plant simulation training programmes for anaesthesia emergencies in two rural Indian hospitals. Methods: Two Indian consultant anaesthetists without experience in medical simulation underwent a 3-day c

Occupational exposure to whole-body vibrations and pregnancy complications : A nationwide cohort study in Sweden

Objectives Pregnancy complications are common contributors to perinatal mortality and morbidity. Still, the cause(s) of gestational hypertensive disorders and diabetes are largely unknown. Some occupational exposures have been inconsistently associated with pregnancy complications, but exposure to whole-body vibrations (WBV) has been largely overlooked even though it has been associated with adver

Thermodynamic modeling, CFD analysis and parametric study of a near-isothermal reciprocating compressor

Reciprocating compressors hold great promise for enhanced efficiency across a wide variety of microscale and macroscale systems. This article investigates the potential of isothermal compression strategies by introducing two modeling approaches for the time-dependent analysis of reciprocating compressors. First, a thermodynamic model is developed based on conservation of mass and energy for a cran

Characterization and antioxidant activity of avenanthramides from selected oat lines developed by mutagenesis technique

From a mutagenized oat population, produced by ethyl methanesulfonate mutagenesis, hulled grains from 17 lines with elevated avenanthramide (AVN) content were selected and their AVN structures, concentrations and antioxidant potentials were determined by HPLC-MS2 and HPLC equipped with an on-line ABTS+ antioxidant detection system. The data obtained showed qualitative and quantitative differences

Evaluation and Hydrological Application of CMADS Reanalysis Precipitation Data against Four Satellite Precipitation Products in the Upper Huaihe River Basin, China

Satellite- and reanalysis-based precipitation products are important data source for precipitation, particularly in areas with a sparse gauge network. Here, five open-access precipitation products, including the newly released China Meteorological Assimilation Driving Datasets for the Soil and Water Assessment Tool (SWAT) model (CMADS) reanalysis dataset and four widely used bias-adjusted satellit

Prenatal diagnosis : The co-production of knowledge and values in medical research and public debate

This chapter examines how prenatal diagnosis was discussed and interpreted when translated from laboratories and clinics into the public arena. It focusses on debates about policy and regulation in the early 1980s. Drawing on the concept of co-production the chapter argues that when groups outside the medical context discussed prenatal diagnosis, other values and norms were mobilized. Thus, in ordThis chapter examines how prenatal diagnosis was discussed and interpreted when translated from laboratories and clinics into the public arena. It focusses on debates about policy and regulation in the early 1980s. Drawing on the concept of co-production the chapter argues that when groups outside the medical context discussed prenatal diagnosis, other values and norms were mobilized. Thus, in ord