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Isobornyl Acrylate

Multidisciplinary collaboration between several European dermatology departments has identified isobornyl acrylate (IBOA; CAS 5888-33-5), once deemed a low-risk sensitizer, as a major culprit contact allergen in glucose sensors and insulin pumps, medical devices used by diabetes patients worldwide. Although the patch test modalities of IBOA have been fairly well characterized, intriguing questions

Massive MIMO Extensions to the COST 2100 Channel Model : Modeling and Validation

To enable realistic studies of massive multiple-input multiple-output systems, the COST 2100 channel model is extended based on measurements. First, the concept of a base station-side visibility region (BS-VR) is proposed to model the appearance and disappearance of clusters when using a physically-large array. We find that BS-VR lifetimes are exponentially distributed, and that the number of BS-V

High dimensional parameter tuning for event generators

Monte Carlo Event Generators are important tools for the understanding of physics at particle colliders like the LHC. In order to best predict a wide variety of observables, the optimization of parameters in the Event Generators based on precision data is crucial. However, the simultaneous optimization of many parameters is computationally challenging. We present an algorithm that allows to tune M

A Decade Frequency Range CMOS Power Amplifier for Sub-6-GHz Cellular Terminals

A wideband 65-nm CMOS power amplifier (PA) is presented, with a decade frequency range from 600 MHz to 6.0 GHz. In this frequency range, the output power exceeds 26.6 dBm and the power gain and power-added efficiency (PAE) exceed 18.1 dB and 49%, respectively. For a 7.5-dB peak-to-average-power-ratio (PAPR) long term evolution (LTE) signal at 1.9 GHz, the circuit provides an average output power o

Construing Scandinavia : A semiotic account of intercultural exchange in theme park design

Evaluation of other cultures is a strong force in a culture's definition of itself. Cultures are formed in encounters that include domination, conflict, and dismissal as much as appreciation and smooth exchange. In this paper, the construction of cultural identity is discussed, with reference to a Scandinavian Theme Park proposal made in cooperation between American design consultants and a local

Bayesian Reconstruction of Past Land Cover From Pollen Data : Model Robustness and Sensitivity to Auxiliary Variables

Realistic depictions of past land cover are needed to investigate prehistoric environmental changes, effects of anthropogenic deforestation, and long-term land cover-climate feedbacks. Observation-based reconstructions of past land cover are rare, and commonly used model-based reconstructions exhibit considerable differences. Recently, Pirzamanbein et al. (2018, 10.1016/j.spasta.2018.03.005, Spati

Large crystal growth for neutron protein crystallography

The use of neutron protein crystallography (NPX) is expanding rapidly, with most structures determined in the last decade. This growth is stimulated by a number of developments, spanning from the building of new NPX beamlines to the availability of improved software for structure refinement. The main bottleneck preventing structural biologists from adding NPX to the suite of methods commonly used

The city that the metro system built : Urban transformations and modalities of integrated planning in Stockholm

This paper investigates how housing and public transport planning in Stockholm has been integrated during the past 20 years through multi-level collaboration. Drawing upon how Stockholm has been portrayed in the literature on transit-oriented development (TOD), that is, as a successful case of integrated land use, housing and public transport planning, this paper suggests that multi-level collabor

Delayed Clinical Manifestation of Parkinson's Disease among Physically Active : Do Participants in a Long-Distance Ski Race Have a Motor Reserve?

Background: Physical activity is associated with reduced risk of Parkinson's disease (PD). The explanations for this association are not completely elucidated. We use long-term PD-incidence data from long-distance skiers to study the relationship between exercise and PD. Objective: We aimed to investigate if physical activity is associated with long-term lower risk of PD and if this association co

Impact of temperature and moisture on the tensile strain of asphalt concrete layers

Moisture in unbound layers and temperature in asphalt layers affect the structural response of pavements, such as the tensile strain at the bottom of asphalt concrete layers. Previous studies have proposed relationships for estimating tensile strain at the bottom of an asphalt layer from Falling Weight Deflectometer (FWD) surface deflection measurements. These relationships have been developed bas

Stable oxygen and carbon isotopes of carbonates in lake sediments as a paleoflood proxy

Lake sediments are increasingly explored as reliable paleoflood archives. In addition to established flood proxies including detrital layer thickness, chemical composition, and grain size, we explore stable oxygen and carbon isotope data as paleoflood proxies for lakes in catchments with carbonate bedrock geology. In a case study from Lake Mondsee (Austria), we integrate high-resolution sediment t

The coin-turning walk and its scaling limit

Let S be the random walk obtained from “coin turning” with some sequence {pn}n≥2, as introduced in [8]. In this paper we investigate the scaling limits of S in the spirit of the classical Donsker invariance principle, both for the heating and for the cooling dynamics. We prove that an invariance principle, albeit with a non-classical scaling, holds for “not too small” sequences, the order const·n−