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In this thesis we characterize the effect of mesenchymal progenitor cells (MPCs) on tumour growth, and show that MPCs can have inhibitory effects on tumour development. We developed a method to subcutaneously transplant tumour cells, cultured in vitro in a pre-formed gelatin matrix, that made it possible to study the early phases of tumour development. Using this method we inoculated rats with gel
Among flowering plants, animals commonly act as pollinators. We showed that fertile moss shoots attract springtails and mites, which in turn carry moss sperm, thereby enhancing the fertilization process. Previously, fertilization of mosses was thought to depend on the capacity of individual sperm to swim through a continuous water layer. The role of microarthropods in moss fertilization resembles
Fifty knees scheduled for a total knee prosthesis were randomized in two groups. Both groups had a noncemented fixation of the porous-coated implants but one group received a prosthesis with ceramic coating on the porous surface of the implant. The knees were evaluated with RSA technique regarding micromotion the first two years. There were less micromotion in the coated group. The results indicat
The melanocyte activity was studied by analysis of the urinary excretion of indolic and cysteinyldopa compounds. One eumelanin marker, 5,6-dihydroxy-indole-2-carboxylic acid was identified and quantified in normal urine. However, its low concentration and sensitivity to oxidation made it less suitable for clinical studies. A methylated derivative of this substance, 6-hydroxy-5-methoxyindole-2-carb
Fibronectin performs essential roles in embryonic development and is prominently expressed during tissue repair. Two forms of fibronectin have been Identified: plasma fibronectin (pFn), which Is expressed by hepatocytes and secreted In soluble form into plasma; and cellular fibronectin (cFn), an insoluble form expressed locally by fibroblasts and other cell types and deposited and assembled into t
Purpose: To assess the intra- and interobserver agreement of ultrasound assessment of clubfoot patho-anatomy in early childhood. Material and Methods: Seventeen clubfeet in 12 children were sequentially scanned by 2 examiners and repeat assessments were carried out independently. Three well-defined imaging planes were chosen to evaluate navicular displacement: the medial malleolus-navicular (MM-N)
Popular Abstract in Swedish Syftet med denna avhandling är att bidra till vår förståelse för vårdutnyttjande och dess förklaringsfaktorer i utvecklingsländer, speciellt i sub-sahariska Afrika. Detta görs genom att fokusera på sjukvårdsutgifter och dess förklaringsfaktorer, samt valet att söka vård för att bota åkomman. Datamaterialete som används kommer från en hushållsundersökning från 1998 omfatThe aim of this thesis is to contribute to our understanding of health care utilisation and its determinants in developing countries, especially in sub-Saharan Africa. This is done by explicitly focusing on health care expenditures and its determinants as well as the choice to seek health care to cure the illness. Firstly, the focus is on a household’s expenditures for health care. The aim of this
In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of
Amplitude integrated EEG (aEEG) recordings from 32 mechanically ventilated infants, gestational age 32 weeks or less, were analysed. All recordings were started within 24 h of birth and continued for at least 50 h. Germinal layer haemorrhage (GLH) was diagnosed by repeated ultrasonography. In six infants neither GLH nor hypocalcaemia were diagnosed; aEEG in these infants rapidly became more active
Microsporidiosis must be regarded as a late opportunistic infection when HIV is advanced. In this article we describe 2 cases of disseminated infection with Encephalitozoon intestinalis. The first case had a local intestinal infection for > 1 y before it disseminated and microsporidia were found intracellularly in sputum. In the second case, spores were initially found in conjunctival cells, sinus
Objective To study oxytocin mRNA in the human endometrium at different phases of the menstrual cycle. Design An exploratory study in non-pregnant women. Setting The Department of Obstetrics and Gynecology, Lund University Hospital, Sweden. Participants Thirty-three women of fertile age undergoing hysterectomy or endometrial curettage on routine benign gynaecologic indications. Methods Endometr
Recension av Bo Eriksson,Lützen 1632. Ett ödesdigert beslut och Ingrid Schubert, Lützen. På spaning efter ett minne.
We investigate the phase transitions in InAs/GaSb quantum wells sandwiched between two wide-gap AlSb barrier layers under an external electric field perpendicular to interfaces. The Schrodinger and the Poisson equations are solved self-consistently to derive the subband dispersions, the potential profile, the electron charge distribution in the InAs layer, and the hole charge distribution in the G
Syftet med detta forskningsprojekt är att undersöka hur ett antal väl dokumenterade experimenthus har fungerat under en tioårsperiod. Undersökningen jämför i första hand uppgifter om energianvändning och de driftfrågor som hör till energianvändningen. Vidare har de boendes upplevda inomhusklimat studerats för att kunna se om, och i så fall hur, experimenthusens låga energianvändning har påverkat d
