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Burkholderia pseudomallei is resistant to a wide range of antibiotics, leading to relapse and recrudescence of melioidosis after cessation of antibiotic therapy. More effective immunotherapies are needed for better management of melioidosis. We evaluated the prophylactic potential of the immunogenic outer membrane protein Omp85 as a vaccine against murine melioidosis. Immunization of BALB/c mice w
In this paper we introduce a fast and robust structure-less alternative to full bundle adjustment. The method is based on optimizing algebraic errors for trilinear constraints from triplets of views. It is shown that the error generated by a triplet of views can be described by a fixed triangular matrix regardless of the number of feature correspondences between the views. The method has been eval
Burkholderia pseudomallei is the etiological agent of melioidosis, a severe infectious disease of humans and animals. The role of the bacterium's proteins expressed in vivo during human melioidosis continues to remain an enigma. This study's aim was to identify B. pseudomallei target proteins that elicit the humoral immune response in infected humans. A small insert genomic expression library was
We provide theory for the computation of convex envelopes of non-convex functionals including an ℓ2-term and use these to suggest a method for regularizing a more general set of problems. The applications are particularly aimed at compressed sensing and low-rank recovery problems, but the theory relies on results which potentially could be useful also for other types of non-convex problems. For op
This note comprises a synthesis of certain results in the theory of exact interpolation between Hilbert spaces. In particular, we examine various characterizations of interpolation spaces and their relations to a number of results in operator theory and in function theory.
Background: Few tools evaluates quality of movements in individuals with knee osteoarthritis (OA). The Test for Substitution Patterns (TSP) is developed to measure the ability to perform five functional movements regarding postural control and altered movement patterns (1). TSP is validated and reliable in individuals with anterior cruciate ligament injury, but has not yet been evaluated in indivi
The scFv antibody towards the Burkholderia pseudomallei exotoxin was previously constructed by phage display and exhibited good specificity towards the exotoxin. We report here the optimization of the scFv expression in an E. coli expression system. Four different E. coli strains (ER2537, TG1, HB2151, and XL1-Blue) were examined for optimal expression of the scFv protein. Two types of carbon sourc
Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by widespread oligodendroglial cytoplasmic inclusions of filamentous α-synuclein, and neuronal loss in autonomic centres, basal ganglia and cerebellar circuits. It has been suggested that primary oligodendroglial α-synucleinopathy may represent a trigger in the pathogenesis of MSA, but the mechanisms un
Devices sharing a network compete for bandwidth, being able to transmit only a limited amount of data. This is for example the case with a network of cameras, that should record and transmit video streams to a monitor node for video surveillance. Adaptive cameras can reduce the quality of their video, thereby increasing the frame compression, to limit network congestion. In this paper, we exploit
Denna bok handlar om hur välfärdsorganisationer kan samskapa värde tillsammans med den som de är till för. Boken belyser betydelsen av att förstå olika verksamheters perspektiv – socialtjänsten, barn- och ungdomspsykiatrin och skolan – genom yrkesgruppernas egna röster för att effektivt kunna ta tillvara varandras kompetenser. I boken föreslås en modell för samskapande i välfärdstjänster som bygge
Climate change is increasingly posing a threat to biodiversity, both through its direct effects on organisms and through indirect effects resulting from changes in land use. Preserving biodiversity is an ethical obligation, but it is also increasingly being realised that biodiversity contributes to ecosystem services, i.e. ecosystem processes important for human needs and prosperity. In order to a
OBJECTIVES: Clitoral surgery on minors diagnosed with differences of sex development is increasingly positioned as a violation of human rights. This qualitative study identified how health professionals (HPs) navigate the contentious issues as they offer care to affected families.DESIGN: Qualitative analysis of audio-recorded semistructured interviews with HPs. All of the interviews were transcrib
