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This article aims to analyze the pursuit of happiness in the characters of three novels published every twenty years or so since 1963. The purpose is to show the real motivations of each character in the pursuit of happiness in each novel. Another objective is to show that Vargas Llosa's characters strive to find happiness despite the more diverse and adverse circumstances in which the author has

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Este trabajo se ciñe exclusivamente al testamento literario que los Nobel de Literatura nos han regalado a modo de discurso. El objetivo ha sido desgranar dichos discursos para ver similitudes o diferencias y extraer las pertinentes reflexiones gracias a un material lleno de talento y altamente cualificado por quienes han dedicado sus vidas al servicio de la literatura. El método ha sido analizar

Insulin secretion and action in North Indian women during pregnancy

AIM: The relative roles(s) of impaired insulin secretion vs. insulin resistance in the development of gestational diabetes mellitus depend upon multiple risk factors and diagnostic criteria. Here, we explored their relative contribution to gestational diabetes as defined by the WHO 1999 (GDM1999) and adapted WHO 2013 (GDM2013) criteria, excluding the 1-h glucose value, in a high-risk Indian popula

Impact of Forced Expiratory Volume in 1 Second (FEV1) and 6-Minute Walking Distance at 3, 6, and 12 Months and Annually on Survival and Occurrence of Bronchiolitis Obliterans Syndrome (BOS) After Lung Transplantation

BACKGROUND Development of bronchiolitis obliterans syndrome (BOS) is a great limitation for patient survival in lung transplantation (LTx). A curative treatment for BOS is still missing, and in terminal stages re-transplantation (Re-LTx) is the only salvation. It is possible to slow the progress of BOS if it is detected at an early stage. This might be possible by assessing pulmonary function patt

Pickering emulsifiers based on hydrophobically modified small granular starches – Part I : Manufacturing and physico-chemical characterization

Small granular starches from rice, quinoa and amaranth were hydrophobized by esterification with octenyl succinic anhydride (OSA) in an aqueous alkaline slurry to obtain series of modified starches at defined intervals (i.e. 0.6, 1.2, 1.8, 2.4, 3.0%). The physical and the physico-chemical properties of the starch particles were characterized by proximate analysis including protein level, amylose l

Two sustainability epistemologies in the marketization of a natural resource

The normative implications of sustainable development mean that different understandings of how sustainability should be achieved will either facilitate or put at risk different values associated with economic, environmental and social aspects of sustainability. By a qualitative analysis of Swedish fishery legislation documents, we analyse and outline the consequences of two different and competin

Atomic layer etching of gallium nitride (0001)

In this work, atomic layer etching (ALE) of thin film Ga-polar GaN(0001) is reported in detail using sequential surface modification by Cl2 adsorption and removal of the modified surface layer by low energy Ar plasma exposure in a standard reactive ion etching system. The feasibility and reproducibility of the process are demonstrated by patterning GaN(0001) films by the ALE process using photores

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This article discusses employment of crowds to make the change in Yemen.

Parameter Estimation - in sparsity we trust

This thesis is based on nine papers, all concerned with parameter estimation. The thesis aims at solving problems related to real-world applications such as spectroscopy, DNA sequencing, and audio processing, using sparse modeling heuristics. For the problems considered in this thesis, one is not only concerned with finding the parameters in the signal model, but also to determine the number of siThis thesis is based on nine papers, all concerned with parameter estimation. The thesis aims at solving problems related to real-world applications such as spectroscopy, DNA sequencing, and audio processing, using sparse modeling heuristics. For the problems considered in this thesis, one is not only concerned with finding the parameters in the signal model, but also to determine the number of si

Organizing for teamwork in healthcare : an alternative to team training?

Purpose: The purpose of this paper is to explore how organizational design could support teamwork and to identify organizational design principles that promote successful teamwork. Design/methodology/approach: Since traditional team training sessions take resources away from production, the alternative approach pursued here explores the promotion of teamwork by means of organizational design. A wi

Molecular characterization of circulating tumor cells from patients with metastatic breast cancer reflects evolutionary changes in gene expression under the pressure of systemic therapy

Resistance to systemic therapy is a major problem in metastatic breast cancer (MBC) that can be explained by initial tumor heterogeneity as well as by evolutionary changes during therapy and tumor progression. Circulating tumor cells (CTCs) detected in a liquid biopsy can be sampled and characterized repeatedly during therapy in order to monitor treatment response and disease progression. Our aim

Intraneural glomus tumor of "uncertain malignant potential" and with BRAF mutation in the median nerve - an unusual case

A glomus tumor of uncertain malignant potential is defined as a glomus tumor with some, but not all, criteria for malignancy and without a known metastasis. Here, we present a rare example presenting in the median nerve in a 40-year-old woman with a long history of severely impaired left median nerve function. A large panel of immunohistochemical stains excluded other diagnoses, and the designatio