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Drought recorded by Ba/Ca in coastal benthic foraminifera
Increasing occurrences of extreme weather events, such as the 2018 drought over northern Europe, are a concerning issue under global climate change. High-resolution archives of natural hydroclimate proxies, such as rapidly accumulating sediments containing biogenic carbonates, offer the potential to investigate the frequency and mechanisms of such events in the past. Droughts alter the barium (Ba)
Supported Lipid Bilayers and the Study of Two-Dimensional Binding Kinetics
Binding between protein molecules on contacting cells is essential in initiating and regulating several key biological processes. In contrast to interactions between molecules in solution, these events are restricted to the two-dimensional (2D) plane of the meeting cell surfaces. However, converting between the more commonly available binding kinetics measured in solution and the so-called 2D bind
Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification
RATIONALE: Vascular calcification is a prominent feature of late-stage diabetes, renal and cardiovascular disease (CVD), and has been linked to adverse events. Recent studies in patients reported that plasma levels of osteomodulin (OMD), a proteoglycan involved in bone mineralisation, associate with diabetes and CVD. We hypothesised that OMD could be implicated in these diseases via vascular calci
Socio-Spatial Theory in Nordic Geography : Intellectual Histories and Critical Interventions
“Perhaps we should forget it" : Reluctant narration in Kazuo Ishiguro’s “A Family Supper”
Linking the fragmentary information provided in Kazuo Ishiguro’s “A Family Supper” (1982) to the first-person narrator’s unwillingness – or perhaps inability – to communicate, this brief note comments on a few passages that highlight the unforthcoming traits of the narrator.
Geographies and theories of geography: An introduction
Sublimated expansionism? Living space ideas in Nordic small-state geopolitics
Home-work embedded in housework
Territorial structure: An early Marxist theorisation of geography
Lillian Gilbreth's Management Desk : Bringing Efficiency Home
Existence of the Dharwar–Bastar–Singhbhum (DHABASI) megacraton since 3.35 Ga : constraints from the Precambrian large igneous province record
We propose a Precambrian megacraton (consisting of two or more ancient cratons), DHABASI in the Indian Shield, which includes the Dharwar, Bastar and Singhbhum cratons. This interpretation is mainly based on seven large igneous provinces (LIPs) that are identified in these three cratons over the age range of c. 3.35–1.77 Ga, a period of at least 1.6 Ga. The absence of any subsequent break-up of DH
Organic micropollutants, heavy metals and pathogens in anaerobic digestate based on food waste
Anaerobic digestate based on food waste is increasingly used as fertilizer in food production. This study examined the characteristics of anaerobic digestate based on food waste from three biogas plants in Sweden. The characterization included measurements of heavy metals (n = 7), chemicals of emerging concern (CECs), such as currently used drugs and pesticides (n = 133), and an extended range of
Foraging on the wing for fish while migrating over changing landscapes : traveling behaviors vary with available aquatic habitat for Caspian terns
Background: Birds that forage while covering distance during migration should adjust traveling behaviors as the availability of foraging habitat changes. Particularly, the behavior of those species that depend on bodies of water to find food yet manage to migrate over changing landscapes may be limited by the substantial variation in feeding opportunities along the route. Methods: Using GPS tracki
EDGE : What shapes the relationship between H i and stellar observables in faint dwarf galaxies?
We show how the interplay between feedback and mass-growth histories introduces scatter in the relationship between stellar and neutral gas properties of field faint dwarf galaxies (M∗ 106, M⊙). Across a suite of cosmological, high-resolution zoomed simulations, we find that dwarf galaxies of stellar masses 105 ≤ M∗ ≤ 106, M⊙ are bimodal in their cold gas content, being either H i-rich or H i-defi
On the formation and stability of cellulose-based emulsions in alkaline systems : Effect of the solvent quality
With amphiphilic properties, cellulose molecules are expected to adsorb at the O/W interface and be capable of stabilizing emulsions. The effect of solvent quality on the formation and stability of cellulose-based O/W emulsions was evaluated in different alkaline systems: NaOH, NaOH-urea and tetrabutylammonium hydroxide (TBAH). The optimal solvency conditions for cellulose adsorption at the O/W in
Interferon regulatory factor-5-dependent CD11c+ macrophages contribute to the formation of rupture-prone atherosclerotic plaques
AIMS: Inflammation is a key factor in atherosclerosis. The transcription factor interferon regulatory factor-5 (IRF5) drives macrophages towards a pro-inflammatory state. We investigated the role of IRF5 in human atherosclerosis and plaque stability.METHODS AND RESULTS: Bulk RNA sequencing from the Carotid Plaque Imaging Project biobank were used to mine associations between major macrophage assoc
Silencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is atheroprotective
Recent studies highlight the importance of lipotoxic damage in aortic cells as the major pathogenetic contributor to atherosclerotic disease. Since the STE20-type kinase STK25 has been shown to exacerbate ectopic lipid storage and associated cell injury in several metabolic organs, we here investigate its role in the main cell types of vasculature. We depleted STK25 by small interfering RNA in hum
Linking silicon isotopic signatures with diatom communities
The use of silicon isotope ratios (expressed as δ30Si) as a paleolimnological proxy in lacustrine systems requires a better understanding of the role of lake processes in setting the δ30Si values of dissolved Si (dSi) in water and in diatom biogenic silica (bSi). We determined the δ30Si of modern dSi (δ30SidSi) and bSi (δ30SibSi) in three lakes in Lassen Volcanic National Park (LAVO), California (
Using Multivariate Imputation by Chained Equations to Predict Redshifts of Active Galactic Nuclei
Redshift measurement of active galactic nuclei (AGNs) remains a time-consuming and challenging task, as it requires follow up spectroscopic observations and detailed analysis. Hence, there exists an urgent requirement for alternative redshift estimation techniques. The use of machine learning (ML) for this purpose has been growing over the last few years, primarily due to the availability of large