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Impact of type 2 diabetes on complications after primary breast cancer surgery : Danish population-based cohort study

Background: Knowledge is sparse on the impact of type 2 diabetes (T2D) on surgical outcomes after breast cancer surgery. This study investigated the association between T2D and risk of complications after primary breast cancer surgery, and evaluated the biological interaction between T2D and co-morbidities. Methods: Using the Danish Breast Cancer Group clinical database, a cohort of all Danish wom

Heritable variation in thermal profiles is associated with reproductive success in the world's largest bird

Organisms inhabiting extreme thermal environments, such as desert birds, have evolved spectacular adaptations to thermoregulate during hot and cold conditions. However, our knowledge of selection for thermoregulation and the potential for evolutionary responses is limited, particularly for large organisms experiencing extreme temperature fluctuations. Here we use thermal imaging to quantify select

Measurement properties of the Body Awareness Scale Movement Quality (BAS MQ) in persons on the autism spectrum : A preliminary Rasch analysis

Background: Persons on the autism spectrum exhibit poorer body awareness than neurotypical persons. Since movement quality may be regarded as an expression of body awareness, assessment of movement quality is important. Sound assessments of measurement properties are essential if reliable decisions about body awareness interventions for persons on the autism spectrum are to be made, but there is i

Designing Sustainable Working Lives and Environments : Work, Health and Leadership in Theory and Practice

Work is central to people’s lives and the course of their life. The opportunities and chances an individual can have in their life are significantly connected to work. Individuals' work is also crucial for organisations, companies and for the whole of society. There is a constant need to make changes and readjustments of working life since these can deeply affect the individual and their employabi

A complex interplay of intra- and extracellular factors regulates the outcome of fetal- and adult-derived MLL-rearranged leukemia

Infant and adult MLL1/KMT2A-rearranged (MLLr) leukemia represents a disease with a dismal prognosis. Here, we present a functional and proteomic characterization of in utero-initiated and adult-onset MLLr leukemia. We reveal that fetal MLL::ENL-expressing lymphomyeloid multipotent progenitors (LMPPs) are intrinsically programmed towards a lymphoid fate but give rise to myeloid leukemia in vivo, hi

FORWARD-BACKWARD SPLITTING WITH DEVIATIONS FOR MONOTONE INCLUSIONS

We propose and study a weakly convergent variant of the forward-backward algorithm for solving structured monotone inclusion problems. Our algorithm features a per-iteration deviation vector, providing additional degrees of freedom. The only requirement on the deviation vector to guarantee convergence is that its norm is bounded by a quantity that can be computed online. This approach offers great

Optical Analysis of Perovskite III-V Nanowires Interpenetrated Tandem Solar Cells

Multi-junction photovoltaics approaches are being explored to mitigate thermalization losses that occur in the absorption of high-energy photons. However, the design of tandem cells faces challenges such as light reflection and parasitic absorption. Nanostructures have emerged as promising solutions due to their anti-reflection properties, which enhances light absorption. III-V nanowires (NWs) sol

Dealing with sportswashing – an exercise in honour and popular culture

Qatar 2022 has become a symbol of sportswashing, a flagpost for discussions about accountability, responsibility, and morality within different sport disciplines, football being a prime example. “Moral violation” has been listed as the crime surrounding sportswashing (Fruh, Archer & Wojtowicz 2023, 103). After frenzied use of the word in connection to the last football world cup 2022, there ca

The Vitamin D Receptor as a Prognostic Marker in Breast Cancer-A Cohort Study

Previous research has indicated an association between the presence of the vitamin D receptor (VDR) in breast cancer tissue and a favorable prognosis. This study aimed to further evaluate the prognostic potential of VDR located in the nuclear membrane or nucleus (liganded). The VDR protein levels were analyzed using immunohistochemistry in tumor samples from 878 breast cancer patients from Lund, S

The role of semantically related gestures in the language comprehension of simultaneous interpreters in noise

Manual co-speech gestures can facilitate language comprehension, especially in adverse listening conditions. However, we do not know whether gestures influence simultaneous interpreters’ language comprehension in adverse listening conditions, and if so, whether this influence is modulated by interpreting experience, or by active simultaneous interpreting (SI). We exposed 24 interpreters and 24 bil

Echocardiographic estimation of pulmonary artery wedge pressure: invasive derivation, validation, and prognostic association beyond diastolic dysfunction grading

Aims: Grading of diastolic function can be useful, but indeterminate classifications are common. We aimed to invasively derive and validate a quantitative echocardiographic estimation of pulmonary artery wedge pressure (PAWP) and to compare its prognostic performance to diastolic dysfunction grading.Methods and results: Echocardiographic measures were used to derive an estimated PAWP (ePAWP) usingAims: Grading of diastolic function can be useful, but indeterminate classifications are common. We aimed to invasively derive and validate a quantitative echocardiographic estimation of pulmonary artery wedge pressure (PAWP) and to compare its prognostic performance to diastolic dysfunction grading.Methods and results: Echocardiographic measures were used to derive an estimated PAWP (ePAWP) using

The relationship between game genre, monetization strategy and symptoms of gaming disorder in a clinical sample of adolescents

Background: Gaming disorder (GD) has been introduced as a new diagnosis in the International Classification of Disease 11 (ICD-11). Currently, there's limited understanding of how various video games may differentially contribute to the risk of developing GD. The main aim of this study was to examine the relationship between individuals' game genre preferences, their preferred games' monetization

Evaluation of heterologous expression in Pichia pastoris of Pine Weevil TRPA1 by GFP and flow cytometry

BACKGROUND: The wasabi receptor, also known as the Transient Receptor Potential Ankyrin 1 (TRPA1) ion channel, is a potential target for development of repellents for insects, like the pine weevil (Hylobius abietis) feeding on conifer seedlings and causing damage in forestry. Heterologous expression of TRPA1 from pine weevil in the yeast Pichia pastoris can potentially provide protein for structur

An in-plane phase-field ductile fracture model for orthotropic paperboard material

A phase-field ductile fracture formulation for orthotropic paperboard materials is proposed, based on an anisotropic, multi-surface elastoplastic model describing the in-plane behavior of paperboard. A variational statement for the finite-step elastoplastic problem is extended to include the variational description of Griffith-type brittle fracture by a phase-field gradient term. The interaction b

Family Reunification for “Paperless” Eritrean Refugees: a Pie in the Sky or a Realisable Right?

Family reunification is, in the words of the European Union (EU) Family Reunification Directive (2003/86/EC), a ‘necessary way of making family life possible’ and preserving family unity. Yet, barriers exist which hinder refugees’ realisation of their right to family reunification. By taking the plight of Eritrean refugees in Europe as a pertinent case study, this paper shows the obstacles that “p