Search results

Objectives To study the effect of a progressively enhanced rest–shade–hydration–hygiene (RSHH) intervention on kidney injury and inflammation biomarkers, and rates of clinical acute kidney injury (AKI) in Nicaraguan sugarcane workers with a very high rate of chronic kidney disease of non-traditional origin (CKDnt). Methods We analysed serum creatinine and C-reactive protein (CRP) and leukocyturia

Alveoli are sac-like structures in the distal lung specialised for gaseous exchange. Alveolar epithelium facilitates efficient respiration through a thin and robust arrangement of type-I (AT1) and type-II (AT2) pneumocytes, supported by tight junctions and surfactant-rich alveolar lining fluid. Chronic diseases like pulmonary fibrosis, asthma, and sarcoidosis compromise alveolar integrity, resulti

Bakgrund: Sepsis är en av de främsta orsakerna till död bland barn globalt och utgör därmed ett allvarligt folkhälsoproblem. Det är ett tidskritiskt tillstånd där tidig identifiering är avgörande men ofta utmanande inom akutsjukvården. Syfte: Syftet var att sammanställa vilka faktorer som påverkar tidig identifiering av sepsis hos barn. Metod: En systematisk litteraturstudie baserat på 12 studier

Bakgrund: Fluktuerande patientflöden och begränsade resurser är vanliga utmaningar på akutmottagningar världen över. I sådana situationer spelar triage en central roll för att säkerställa rättvis bedömning och prioritering av patienter. Det är därför viktigt att undersöka akutsjuksköterskors upplevelser av triage på akutmottagningen, då det kan belysa potentiella hinder och bidra till förbättringa

Beijing is particularly prone to frequent wintertime haze episodes. In this study, we introduce the FLEXPART (FLEXible PARTicle dispersion model) and SOSAA (the model to Simulate the concentration of Organic vapors, Sulfuric Acid, and Aerosols) modeling system for air quality analysis and applied the newly developed modeling system to a severe pollution episode during a case study in Beijing in No

Neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases, are associated with the formation of amyloid fibrils. The DNAJB6b (JB6) chaperone greatly inhibits the disease-related self-assembly of amyloid peptides in an ATP-independent manner. The molecular basis of this process is, however, not understood. Here, we studied the low complexity linker between the N- and C-terminal doma

This paper introduces a novel approach for transitioning from high-granularity Ray-Tracing (RT) channel simulations to channel emulation, accompanied by an over-the-air test. The RT simulation is performed on a Vehicle-to-Vehicle (V2V) communication drive scenario generating basis for channel emulation in a channel emulator. The channel simulation, and the accompanying channel emulation, also enab

The present work provides a new perspective on super adiabatic combustion (SAC) of fuel/air mixtures involving methane, ethane, propane, butane, heptane, iso-octane, 1-hexene, toluene, ammonia, and hydrogen. The simulations cover the temperature range of 1200–2000 K, initial pressures of 1–50 atm, and equivalence ratios of 0.5–2.0. The detailed chemical kinetic mechanism C3MechV3.5 has been used f

Over the past decade, the far-right has become normalised globally. The tolerance and wilful welcoming of these once-shunned ideologies challenge the weakened modern liberal order and signify its limitations as modernity’s symbolic authority. This phenomenon involves an unprecedented ontology in which far-right fantasies of “stolen” ethnocultural wholeness and supremacy propagate through social me

The increasing threat of soil degradation presents significant challenges to soil health, especially within agroecosystems that are vital for food security, climate regulation, and economic stability. This growing concern arises from intricate interactions between land use practices and climatic conditions, which, if not addressed, could jeopardize sustainable development and environmental resilie

Considering the distinct etiological pathways and molecular characteristics of different lung cancer subtypes, it is crucial to develop subtype-specific prevention strategies and therapeutic targets. This study aimed to identify protein biomarkers and potential therapeutic targets for specific subtypes of lung cancer by integrating population-based observational studies and Mendelian randomisation

Background: Air pollution has been linked to breast cancer risk, but previous studies have seldom considered specific exposure windows, like pregnancy. During pregnancy the breast undergoes substantial changes and exposures may have a stronger impact than if they occurred during other time periods. This study aims to identify associations between ambient air pollution exposure during pregnancy and

Purpose of Review: Summarize recent literature on: understanding of and emotional reactions to type 1 diabetes (T1D) risk; willingness to be screened; behavioral responses to T1D-risk screening results; and provider attitudes/concerns about general population screening. Recent Findings: Difficulty understanding what it means to be at increased risk for T1D is common; anxiety about increased risk m

Purpose: The Paleolithic Diet Fraction (PDF) estimates the proportion of absolute dietary intake derived from food groups included in the Paleolithic diet. In the Malmö Diet and Cancer Study (MDCS), higher PDF and lower systemic low-grade chronic inflammation (SLGCI) have been associated with lower cardiometabolic morbidity and mortality. We examined associations between PDF and SLGCI in the MDCS.

Hypertrophic cardiomyopathy (HCM), the most common inherited cardiomyopathy, is characterized by phenotypic and genetic heterogeneity. The present study describes the genotype data of a Swedish cohort of patients with HCM, the largest genetics study on Swedish HCM patients to date. The primary aims of this study were to unravel the main genetic findings and explore genotype–phenotype associations

Introduction: Mycobacteria have a unique hydrophobic membrane with several lipid-enriched layers that are low in permeability, setting them apart from other bacteria. This complex structure, consisting of three distinct layers is crucial for cell growth, virulence, and providing a barrier to antibiotics. Previously, we identified a plectasin variant, NZX, which showed activity against Mycobacteriu

Background: Optimal long-term follow-up (LTFU) care for survivors of childhood, adolescent and young adult (CAYA) cancer can improve or maintain their quality of life by prevention and early treatment of late effects. However, optimal LTFU care is not provided to all CAYA cancer survivors. This systematic review sought to identify associated barriers, facilitators and other factors of LTFU care fo

Cross-country regressions suggest that protectionism supported industrialization. I leverage novel and highly granular data covering Swedish manufacturing firms to estimate the impact of Sweden’s shift toward protectionism after 1891 on establishment-level development. Using mainly two-way fixed effects regressions, I show that tariff increases had a heterogeneous impact across establishments: ini