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Studies of the pathogenesis of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura

Popular Abstract in Swedish Hemolytiskt uremiskt syndrom (HUS) och trombotiskt trombocytopen purpura (TTP) är allvarliga sjukdomar hos barn och vuxna. HUS kännetecknas av mikroangiopatisk hemolytisk anemi (blodbrist med nedbrytning av röda blodkroppar), trombocytopeni (låga blodplättar) och akut njursvikt. Det är den vanligaste orsaken till akut njursvikt hos barn. Typisk HUS utlöses av tarminfektThis study investigated the pathogenesis of hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). (1) The relative roles of lipopolysaccharide and Shiga-like toxin-2 were studied in a mouse model of Escherichia coli O157:H7 infection. Both factors were found to be important for the virulence of the strain and contributed in an additive manner. The mouse model mimicked cert

Towards optimal content replication and request routing in content delivery networks

Cooperative content replication and request routing (C2R3) has emerged as a promising technique to enhance the efficiency of content delivery networks (CDN). Most existing approaches to C2R3 focus on efficient bandwidth usage and assume a hierarchical CDN architecture targeted towards the delivery of specific content types (e.g., video). Therefore, C2R3 problem of covering the broad range of conte

The Technology and Economy of Farm-Scale, High-Solids Anaerobic Digestion of Plant Biomass

Anaerobic digestion is a microbially mediated process occurring in nature in the absence of oxygen and other non-carbonaceous electron acceptors. The majority of the carbon of the organic matter degraded in the process is transformed into carbon dioxide and methane. Most of the energy potential of the degraded material is conserved in the methane, thus providing a renewable energy carrier, which c