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Escape to the country: A reaction-driven rural renaissance on a Swedish island post Covid-19

The COVID-19 pandemic could be driving more households to migrate out of cities and to the countryside, but this might result in an increased demand for access to green space which, in the long run, may cause a widening of social inequalities in rural areas. On the contrary, if planned for, it could provide an opportunity for repopulation and regeneration. This article explores the underlying caus

Rural gentrification and heritage-led resistance: walking through a manifestation of nostalgia or an active social response?

Rural gentrification, amenity-led in-migration and displacement in more attractive parts of the countryside are taking up more of the rural discourse. Along this, the centrality of landscape, as a driver for gentrification and as something affected by the same notion, is establishing. This paper explores the paradox of how people move to a certain area because they find that particular landscape a

CONCEPTUALIZING THE IMPACT OF DIGITAL BUSINESS MODELS ON PRIVACY CONCERNS

Digital technologies have enabled novel forms and reconfigurations of value creation, delivery, and capture. These new reconfigurations challenge the conventional notion of value creation with digital business models. On that premise, the widening of privacy concerns, alert us that organizations of the elite digital, like Netflix, Amazon, and Spotify, design technology to feed on personal data, ba

Consensus recommendations for clinical assessment tools for the diagnosis of posterior cortical atrophy syndrome from the Atypical AD PIA of ISTAART

INTRODUCTION: Delay in diagnosis of posterior cortical atrophy (PCA) syndrome is common, and the lack of familiarity with assessment tools for identifying visual cortical dysfunction is a contributing factor. We propose recommendations for the approach to the evaluation of PCA clinical features during the office visit, the neuropsychological evaluation, and the research setting. A recommended scre

Rational engineering of Luminiphilus syltensis(R)-selective amine transaminase for the acceptance of bulky substrates

Despite the plethora of information on (S)-selective amine transaminases, the (R)-selective ones are still not well-studied; only a few structures are known to date, and their substrate scope is limited, apart from a few stellar works in the field. Herein, the structure ofLuminiphilus syltensis(R)-selective amine transaminase is elucidated to facilitate engineering towards variants active on bulki

Occupational exposure to epoxy components and risk of dermatitis : A registry-based follow-up study of the wind turbine industry

Background: Allergic contact allergy and dermatitis are frequently reported among epoxy-exposed workers. Objectives: To determine the risk of dermatitis associated with epoxy exposure. Methods: We followed 825 epoxy-exposed and 1091 non-exposed blue-collar workers, and 493 white-collar workers of a Danish wind turbine blade factory during 2017–2022 with linked data from national health registers o

Transcription factor networks link B-lymphocyte development and malignant transformation in leukemia

Rapid advances in genomics have opened unprecedented possibilities to explore the mutational landscapes in malignant diseases, such as B-cell acute lymphoblastic leukemia (B-ALL). This disease is manifested as a severe defect in the production of normal blood cells due to the uncontrolled expansion of transformed B-lymphocyte progenitors in the bone marrow. Even though classical genetics identifie

How can the findings of the EMAX trial on long-acting bronchodilation in chronic obstructive pulmonary disease be applied in the primary care setting?

This review addresses outstanding questions regarding initial pharmacological management of chronic obstructive pulmonary disease (COPD). Optimizing initial treatment improves clinical outcomes in symptomatic patients, including those with low exacerbation risk. Long-acting muscarinic antagonist/long-acting β2-agonist (LAMA/LABA) dual therapy improves lung function versus LAMA or LABA monotherapy,

Synthesis of highbush blueberry pollination research reveals region-specific differences in the contributions of honeybees and wild bees

Highbush blueberry production has expanded worldwide in recent decades. To safeguard future yields, it is essential to understand if insect pollination is limiting current blueberry production and which insects contribute to pollination in different production regions. We present a systematic review including a set of meta-analyses on insect-mediated pollination in highbush blueberry. We summarize

Factors promoting hunting groups’ sustainable harvest of moose in a co-management system

Collaboration between and within management levels and involvement of local communities (co-management) increases sustainable management of natural resources. In Finland, moose (Alces alces) are harvested by hunting groups within a co-management system, providing meat and social benefits. We computed the 14-year change in moose harvest (2007–2020) for 4320 hunting groups. Moose harvest declined on

Human macrophage migration inhibitory factor potentiates mesenchymal stromal cell efficacy in a clinically relevant model of allergic asthma

Current asthma therapies focus on reducing symptoms but fail to restore existing structural damage. Mesenchymal stromal cell (MSC) administration can ameliorate airway inflammation and reverse airway remodeling. However, differences in patient disease microenvironments seem to influence MSC therapeutic effects. A polymorphic CATT tetranucleotide repeat at position 794 of the human macrophage migra

Opera Nova : makt, kärlek, remix

Opera Nova tar sin utgångspunkt i de rollfunktioner vi som individer väljer i olika grupper och situationer. Hur fria är vi i våra val? Tillsammans med publiken undersöker vi bilder av makt och genus på operascenen och i verkligheten. Vi undersöker härskartekniker och pratar om hur man kan bryta upp oönskade maktmönster. Vi arbetar med improvisation och leker fram operascener i olika klassiska musThe ensemble Operaimprovisatörerna investigated ways of deconstructing images of gender and power in opera and opera improvisation performance, by changing roles and using different readings, such as realism, parody and movement. I initiated the project inspired by a theoretical vantage point of post-structuralfeminism (Wilén, 2017, p. 17). The project focused on "interchange of traditional roles

Can 24 h of ambulatory ECG be used to triage patients to extended monitoring?

Background: Access to long-term ambulatory recording to detect atrial fibrillation (AF) is limited for economical and practical reasons. We aimed to determine whether 24 h ECG (24hECG) data can predict AF detection on extended cardiac monitoring. Methods: We included all US patients from 2020, aged 17–100 years, who were monitored for 2–30 days using the PocketECG device (MEDICALgorithmics), witho

A cross-sectional study of career paths for Swedish registered nurses with a doctoral degree : When aspirations and possibilities collide

Registered nurses with a doctoral degree are important for the quality of care, nursing education, and nursing research. Still, postgraduate career paths are criticized for being too vague. To enable career path development, mapping of the current situation appears fundamental. The objective was therefore to chart the current professional positions and work conditions and to explore the future car

Estimates of Temporal Edge Detection Filters in Human Vision

Edge detection is an important process in human visual processing. However, as far as we know, few attempts have been made to map the temporal edge detection filters in human vision. To that end, we devised a user study and collected data from which we derived estimates of human temporal edge detection filters based on three different models, including the derivative of the infinite symmetric expo

Measuring body temperature in birds – the effects of sensor type and placement on estimated temperature and metabolic rate

Several methods are routinely used to measure avian body temperature, but different methods vary in invasiveness. This may cause stress-induced increases in temperature and/or metabolic rate and, hence, overestimation of both parameters. Choosing an adequate temperature measurement method is therefore key to accurately characterizing an animal’s thermal and metabolic phenotype. Using great tits (P

Swift Prosodic Modulation of Lexical Access : Brain Potentials From Three North Germanic Language Varieties

Purpose: According to most models of spoken word recognition, listeners probabilistically activate a set of lexical candidates, which is incrementally updated as the speech signal unfolds. Speech carries segmental (speech sound) as well as suprasegmental (prosodic) information. The role of the latter in spoken word recognition is less clear. We investigated how suprasegments (tone and voice qualit